THE EFFICACY OF MELDONIUM IN PATIENTS WITH CHRONIC HEART FAILURE OF ISCHEMIC ETIOLOGY WITH COMORBIDITIES

Нeart failure is common both in cardiac and noncardiac disease. We conducted a study that showed high efficacy and safety of meldonium in patients with heart failure and comorbidity. The ability of meldonium reduce the severity of heart failure, improve the quality of life of patients, have a beneficial effect on lipid and carbohydrate metabolism, renal function in patients with concomitant  diabetes  mellitus.  Marked positive  impact on  meldonium  autonomic  manifestations  of  cardiac autonomic neuropathy and for diabetic peripheral sensorimotor neuropathy. In addition, meldonium use in patients with hypertension has a  positive effect on cognitive status. Мeldonium reduces the degree of heart failure, improves the quality of life, lipid and carbohydrate metabolism,  renal  function, manifestation  of  autonomic  cardiac neuropathy and  for  diabetic  peripheral sensorimotor neuropathy in patients with concomitant diabetes mellitus, Application meldonium in patients with hypertension have a positive impact on cognitive status