680 research outputs found
Evolution of Online User Behavior During a Social Upheaval
Social media represent powerful tools of mass communication and information
diffusion. They played a pivotal role during recent social uprisings and
political mobilizations across the world. Here we present a study of the Gezi
Park movement in Turkey through the lens of Twitter. We analyze over 2.3
million tweets produced during the 25 days of protest occurred between May and
June 2013. We first characterize the spatio-temporal nature of the conversation
about the Gezi Park demonstrations, showing that similarity in trends of
discussion mirrors geographic cues. We then describe the characteristics of the
users involved in this conversation and what roles they played. We study how
roles and individual influence evolved during the period of the upheaval. This
analysis reveals that the conversation becomes more democratic as events
unfold, with a redistribution of influence over time in the user population. We
conclude by observing how the online and offline worlds are tightly
intertwined, showing that exogenous events, such as political speeches or
police actions, affect social media conversations and trigger changes in
individual behavior.Comment: Best Paper Award at ACM Web Science 201
Business model configuration and dynamics for technology commercialization in mature markets
Purpose: The food industry is a well-established and complex industry. New entrants attempting to penetrate it via the commercialization of a new technological innovation could face high uncertainty and constraints. The capability to innovate through collaboration and to identify suitable strategies and innovative business models can be particularly important for bringing a technological innovation to this market. However, although the potential for these capabilities has been advocated, we still lack a complete understanding of how new ventures could support the technology commercialization process via the development of business models. Design/methodology/approach: To address this gap, this paper 1) builds a conceptual framework that knits together the different bodies of extant literature (i.e. entrepreneurship, strategy and innovation) to analyse the business model innovation processes associated with the exploitation of emerging technologies; 2) determines the suitability of the framework using data from the exploratory case study of ISIT3D - a firm which has started to exploit 3D printing in the food industry; 3) improves the initial conceptual framework with the findings that emerged in the case study.
Findings: From this analysis it emerged that: 1) companies could use more than one BM at a time; hence, BM innovation processes could coexist and be run in parallel; 2) the facing of high uncertainty might lead firms to choose a closed and/or a familiar business model, while explorative strategies could be pursued with open business models; 3) significant changes in strategies during the technology commercialisation process are not necessarily reflected in a radical change in the business model and 4) firms could deliberately adopt interim strategies and BMs as means to identify the more suitable ones to reach the market.
Originality/value: This case study illustrates how firms could innovate the processes of their BM development to face the uncertainties linked with the entry into a mature and highly conservative industry (food).This research work was supported by the Roma Tre Scholarship and the âBit by bit: Capturing the value from the digital fabrication revolutionâ project, funded by the UK Engineering and Physical Science Research Council (EPSRC) and Economic and Social Research Council (ESRC) (Ref. EP/K039598/1)
Pricing Problems with Buyer Preselection
We investigate the problem of preselecting a subset of buyers (also called agents) participating in a market so as to optimize the performance of stable outcomes. We consider four scenarios arising from the combination of two tability notions, namely market envy-freeness and agent envy-freeness, with the two state-of-the-art objective functions of ocial welfare and sellerâs revenue. When insisting on market envy-freeness, we prove that the problem cannot be pproximated within n 1âΔ (with n being the number of buyers) for any Δ > 0, under both objective functions; we also provide approximation algorithms with an approximation ratio tight up to subpolynomial multiplicative factors for social welfare and the sellerâs revenue. The negative result, in particular, holds even for markets with single-minded buyers. We also prove that maximizing the sellerâs revenue is NP-hard even for a single buyer, thus closing a previous open question. Under agent envy-freeness and for both objective functions, instead, we design a polynomial time lgorithm transforming any stable outcome for a market involving any subset of buyers into a stable outcome for the whole market without worsening its performance. This result creates an interesting middle-ground situation where, if on the one hand buyer preselection cannot improve the performance of agent envy-free outcomes, on the other one it can be used as a tool for simplifying the combinatorial structure of the buyersâ valuation functions in a given market. Finally, we consider the restricted case of multi-unit markets, where all items are of the same type and are assigned the same price. For these markets, we show that preselection may improve the performance of stable outcomes in all of the four considered scenarios, and design corresponding approximation algorithms
Competition among memes in a world with limited attention
The wide adoption of social media has increased the competition among ideas for our finite attention. We employ a parsimonious agent-based model to study whether such a competition may affect the popularity of different memes, the diversity of information we are exposed to, and the fading of our collective interests for specific topics. Agents share messages on a social network but can only pay attention to a portion of the information they receive. In the emerging dynamics of information diffusion, a few memes go viral while most do not. The predictions of our model are consistent with empirical data from Twitter, a popular microblogging platform. Surprisingly, we can explain the massive heterogeneity in the popularity and persistence of memes as deriving from a combination of the competition for our limited attention and the structure of the social network, without the need to assume different intrinsic values among ideas
Observation of Fermi-Pasta-Ulam-Tsingou Recurrence and Its Exact Dynamics
One of the most controversial phenomena in nonlinear dynamics is the reappearance of initial
conditions. Celebrated as the Fermi-Pasta-Ulam-Tsingou problem, the attempt to understand how these
recurrences form during the complex evolution that leads to equilibrium has deeply influenced the entire
development of nonlinear science. The enigma is rendered even more intriguing by the fact that integrable
models predict recurrence as exact solutions, but the difficulties involved in upholding integrability for a
sufficiently long dynamic has not allowed a quantitative experimental validation. In natural processes,
coupling with the environment rapidly leads to thermalization, and finding nonlinear multimodal systems
presenting multiple returns is a long-standing open challenge. Here, we report the observation of more than
three Fermi-Pasta-Ulam-Tsingou recurrences for nonlinear optical spatial waves and demonstrate the
control of the recurrent behavior through the phase and amplitude of the initial field. The recurrence period
and phase shift are found to be in remarkable agreement with the exact recurrent solution of the nonlinear
Schrödinger equation, while the recurrent behavior disappears as integrability is lost. These results identify
the origin of the recurrence in the integrability of the underlying dynamics and allow us to achieve one of
the basic aspirations of nonlinear dynamics: the reconstruction, after several return cycles, of the exact
initial condition of the system, ultimately proving that the complex evolution can be accurately predicted in
experimental conditions
Sharing the cost of multicast transmissions in wireless networks
AbstractA crucial issue in non-cooperative wireless networks is that of sharing the cost of multicast transmissions to different users residing at the stations of the network. Each station acts as a selfish agent that may misreport its utility (i.e., the maximum cost it is willing to incur to receive the service, in terms of power consumption) in order to maximize its individual welfare, defined as the difference between its true utility and its charged cost. A provider can discourage such deceptions by using a strategyproof cost sharing mechanism, that is a particular public algorithm that, by forcing the agents to truthfully reveal their utility, starting from the reported utilities, decides who gets the service (the receivers) and at what price. A mechanism is said budget balanced (BB) if the receivers pay exactly the (possibly minimum) cost of the transmission, and ÎČ-approximate budget balanced (ÎČ-BB) if the total cost charged to the receivers covers the overall cost and is at most ÎČ times the optimal one, while it is efficient if it maximizes the sum of the receiversâ utilities minus the total cost over all receiversâ sets. In this paper, we first investigate cost sharing strategyproof mechanisms for symmetric wireless networks, in which the powers necessary for exchanging messages between stations may be arbitrary and we provide mechanisms that are either efficient or BB when the power assignments are induced by a fixed universal spanning tree, or (3ln(k+1))-BB (k is the number of receivers), otherwise. Then we consider the case in which the stations lay in a d-dimensional Euclidean space and the powers fall as 1/dα, and provide strategyproof mechanisms that are either 1-BB or efficient for α=1 or d=1. Finally, we show the existence of 2(3d-1)-BB strategyproof mechanisms in any d-dimensional space for every α⩟d. For the special case of d=2 such a result can be improved to achieve 12-BB mechanisms
An experimental and theoretical study of the resonant Auger spectrum of the ethene molecule
Resonant Auger spectra of the ethene molecule excited at energies across the
C1s â Ï* energy band are reported. Our measurements address the unexpected
variation of the intensity of the A state with respect to the other singly ionized
valence states. An approach, based on group theory and calculations using
Coulomb 4-center integrals, is proposed to explain the behaviour of the intensity
of the ground state and excited states of the ion upon resonant excitation. The
new method provides a calculationally inexpensive route to predict relative
intensities of different resonant Auger bands in polyatomic molecules, without
the need for an exhaustive knowledge of the potential energy surfaces of the
electronic states involved
Optimal network topologies: Expanders, Cages, Ramanujan graphs, Entangled networks and all that
We report on some recent developments in the search for optimal network
topologies. First we review some basic concepts on spectral graph theory,
including adjacency and Laplacian matrices, and paying special attention to the
topological implications of having large spectral gaps. We also introduce
related concepts as ``expanders'', Ramanujan, and Cage graphs. Afterwards, we
discuss two different dynamical feautures of networks: synchronizability and
flow of random walkers and so that they are optimized if the corresponding
Laplacian matrix have a large spectral gap. From this, we show, by developing a
numerical optimization algorithm that maximum synchronizability and fast random
walk spreading are obtained for a particular type of extremely homogeneous
regular networks, with long loops and poor modular structure, that we call
entangled networks. These turn out to be related to Ramanujan and Cage graphs.
We argue also that these graphs are very good finite-size approximations to
Bethe lattices, and provide almost or almost optimal solutions to many other
problems as, for instance, searchability in the presence of congestion or
performance of neural networks. Finally, we study how these results are
modified when studying dynamical processes controlled by a normalized (weighted
and directed) dynamics; much more heterogeneous graphs are optimal in this
case. Finally, a critical discussion of the limitations and possible extensions
of this work is presented.Comment: 17 pages. 11 figures. Small corrections and a new reference. Accepted
for pub. in JSTA
A case report of treatment of a streptococcal brain abscess with ceftobiprole supported by the measurement of drug levels in the cerebrospinal fluid
In this paper, we describe the case of a patient admitted to our hospital because of a brain abscess due to Streptococcus intermedius. The management of brain abscess is challenging given the limited potential drug options with effective penetration into both the central nervous system and the abscess capsule to achieve adequate therapeutic concentrations. Due to the high anti-streptococcal activity of ceftobiprole and the availability of ceftobiprole therapeutic drug monitoring in our hospital, we decided to treat the patient with ceftobiprole. To maximize the antimicrobial effect of ceftobiprole, we chose a prolonged intravenous infusion, and we monitored its concentrations in both plasma and cerebrospinal fluid
UniPR1331: small Eph/ephrin antagonist beneficial in intestinal inflammation by interfering with type-B signaling
Eph receptors, comprising A and B classes, interact with cell-bound ephrins generating bidirectional signaling. Although mainly related to carcinogenesis and organogenesis, the role of Eph/ephrin system in inflammation is growingly acknowledged. Recently, we showed that EphA/ephrin-A proteins can modulate the acute inflammatory responses induced by mesenteric ischemia/reperfusion, while beneficial effects were granted by EphB4, acting as EphB/ephrin-B antagonist, in a murine model of Crohnâs disease (CD). Accordingly, we now aim to evaluate the effects of UniPR1331, a pan-Eph/ephrin antagonist, in TNBS-induced colitis and to ascertain whether UniPR1331 effects can be attributed to A- or B-type signaling interference. The potential anti-inflammatory action of UniPR1331 was compared to those of the recombinant proteins EphA2, a purported EphA/ephrin-A antagonist, and of ephrin-A1-Fc and EphA2-Fc, supposedly activating forward and reverse EphA/ephrin-A signaling, in murine TNBS-induced colitis and in stimulated cultured mononuclear splenocytes. UniPR1331 antagonized the inflammatory responses both in vivo, mimicking EphB4 protection, and in vitro; EphA/ephrin-A proteins were inactive or only weakly effective. Our findings represent a further proof-of-concept that blockade of EphB/ephrin-B signaling is a promising pharmacological strategy for CD management and highlight UniPR1331 as a novel drug candidate, seemingly working through the modulation of immune responses
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