5,503 research outputs found
The Planck Surveyor mission: astrophysical prospects
Although the Planck Surveyor mission is optimized to map the cosmic microwave
background anisotropies, it will also provide extremely valuable information on
astrophysical phenomena. We review our present understanding of Galactic and
extragalactic foregrounds relevant to the mission and discuss on one side,
Planck's impact on the study of their properties and, on the other side, to
what extent foreground contamination may affect Planck's ability to accurately
determine cosmological parameters. Planck's multifrequency surveys will be
unique in their coverage of large areas of the sky (actually, of the full sky);
this will extend by two or more orders of magnitude the flux density interval
over which mm/sub-mm counts of extragalactic sources can be determined by
instruments already available (like SCUBA) or planned for the next decade (like
the LSA-MMA or the space mission FIRST), which go much deeper but over very
limited areas. Planck will thus provide essential complementary information on
the epoch-dependent luminosity functions. Bright radio sources will be studied
over a poorly explored frequency range where spectral signatures, essential to
understand the physical processes that are going on, show up. The
Sunyaev-Zeldovich effect, with its extremely rich information content, will be
observed in the direction of a large number of rich clusters of Galaxies.
Thanks again to its all sky coverage, Planck will provide unique information on
the structure and on the emission properties of the interstellar medium in the
Galaxy. At the same time, the foregrounds are unlikely to substantially limit
Planck's ability to measure the cosmological signals. Even measurements of
polarization of the primordial Cosmic Microwave background fluctuations appear
to be feasible.Comment: 20 pages, Latex (use aipproc2.sty, aipproc2.cls, epsfig.sty), 10
PostScript figures; invited review talk, Proc. of the Conference: "3 K
Cosmology", Roma, Italy, 5-10 October 1998, AIP Conference Proc, in press
Note: Figures 6 and 7 have been replaced by new and correct version
Optically Faint Microjansky Radio Sources
We report on the identifications of radio sources from our survey of the
Hubble Deep Field and the SSA13 fields, both of which comprise the deepest
radio surveys to date at 1.4 GHz and 8.5 GHz respectively. About 80% of the
microjansky radio sources are associated with moderate redshift starburst
galaxies or AGNs within the I magnitude range of 17 to 24 with a median of I =
22 mag. Thirty-one (20%) of the radio sources are: 1) fainter than 25 mag,
with two objects in the HDF 28.5, 2) often identified with very red
objects 4, and 3) not significantly different in radio properties than
the brighter objects. We suggest that most of these objects are associated with
heavily obscured starburst galaxies with redshifts between 1 and 3. However,
other mechanisms are discussed and cannot be ruled out with the present
observations.Comment: to appear in Astrophysical Journal Letters, 3 figures, 1 tabl
Hydrodynamic fluctuations and instabilities in ordered suspensions of self-propelled particles
We construct the hydrodynamic equations for {\em suspensions} of
self-propelled particles (SPPs) with spontaneous orientational order, and make
a number of striking, testable predictions:(i) SPP suspensions with the
symmetry of a true {\em nematic} are {\em always} absolutely unstable at long
wavelengths.(ii) SPP suspensions with {\em polar}, i.e., head-tail {\em
asymmetric}, order support novel propagating modes at long wavelengths,
coupling orientation, flow, and concentration. (iii) In a wavenumber regime
accessible only in low Reynolds number systems such as bacteria, polar-ordered
suspensions are invariably convectively unstable.(iv) The variance in the
number N of particles, divided by the mean , diverges as in
polar-ordered SPP suspensions.Comment: submitted to Phys Rev Let
Using answer set programming to integrate RNA expression with signalling pathway information to infer how mutations affect ageing.
A challenge of systems biology is to integrate incomplete knowledge on pathways with existing experimental data sets and relate these to measured phenotypes. Research on ageing often generates such incomplete data, creating difficulties in integrating RNA expression with information about biological processes and the phenotypes of ageing, including longevity. Here, we develop a logic-based method that employs Answer Set Programming, and use it to infer signalling effects of genetic perturbations, based on a model of the insulin signalling pathway. We apply our method to RNA expression data from Drosophila mutants in the insulin pathway that alter lifespan, in a foxo dependent fashion. We use this information to deduce how the pathway influences lifespan in the mutant animals. We also develop a method for inferring the largest common sub-paths within each of our signalling predictions. Our comparisons reveal consistent homeostatic mechanisms across both long- and short-lived mutants. The transcriptional changes observed in each mutation usually provide negative feedback to signalling predicted for that mutation. We also identify an S6K-mediated feedback in two long-lived mutants that suggests a crosstalk between these pathways in mutants of the insulin pathway, in vivo. By formulating the problem as a logic-based theory in a qualitative fashion, we are able to use the efficient search facilities of Answer Set Programming, allowing us to explore larger pathways, combine molecular changes with pathways and phenotype and infer effects on signalling in in vivo, whole-organism, mutants, where direct signalling stimulation assays are difficult to perform. Our methods are available in the web-service NetEffects: http://www.ebi.ac.uk/thornton-srv/software/NetEffects
Periodic table of 3d-metal dimers and their ions
The ground states of the mixed 3d-metal dimers TiV, TiCr, TiMn, TiFe, TiCo, TiNi, TiCu, TiZn, VCr, VMn, VFe, VCo, VNi, VCu, VZn, CrMn, CrFe, CrCo, CrNi, CrCu, CrZn, MnFe, MnCo, MnNi, MnCu, MnZn, FeCo, FeNi, FeCu, FeZn, CoNi, CoCu, CoZn, NiCu, NiZn, and CuZn along with their singly negatively and positively charged ions are assigned based on the results of computations using density functional theory with generalized gradient approximation for the exchange-correlation functional. Except for TiCo and CrMn, our assignment agrees with experiment. Computed spectroscopic constants (re,ωe,Do) are in fair agreement with experiment. The ground-state spin multiplicities of all the ions are found to differ from the spin multiplicities of the corresponding neutral parents by ±1. Except for TiV, MnFe, and MnCu, the number of unpaired electrons, N, in a neutral ground-state dimer is either N1+N2 or |N1−N2|,where N1 and N2 are the numbers of unpaired 3d electrons in the 3dn4s1 occupation of the constituent atoms. Combining the present and previous results obtained at the same level of theory for homonuclear [Gutsev and Bauschlicher, J. Phys. Chem. A 107, 4755 (2003)] 3d-metal and ScX (X=Ti–Zn) dimers [Gutsev, Bauschlicher, and Andrews, in Theoretical Prospects of Negative Ions, edited by J. Kalcher (Research Signpost, Trivandrum, 2002), pp. 43–60] allows one to construct “periodic” tables of all 3d-metal dimers along with their singly charged ions
Radio Wavelength Constraints on the Sources of the Far Infrared Background
The cosmic far infrared background detected recently by the COBE-DIRBE team
is presumably due, in large part, to the far infrared (FIR) emission from all
galaxies. We take the well-established correlation between FIR and radio
luminosity for individual galaxies and apply it to the FIR background. We find
that these sources make up about half of the extragalactic radio background,
the other half being due to AGN. This is in agreement with other radio
observations, which leads us to conclude that the FIR-radio correlation holds
well for the very faint sources making up the FIR background, and that the FIR
background is indeed due to star-formation activity (not AGN or other possible
sources). If these star-forming galaxies have a radio spectral index between
0.4 and 0.8, and make up 40 to 60% of the extragalactic radio background, we
find that they have redshifts between roughly 1 and 2, in agreement with recent
estimates by Madau et al. of the redshift of peak star-formation activity. We
compare the observed extragalactic radio background to the integral over the
logN-logS curve for star-forming radio sources, and find that the slope of the
curve must change significantly below about 1 microjansky. At 1 microjansky,
the faint radio source counts predict about 25 sources per square arcminute,
and these will cause SIRTF to be confusion limited at 160micron.Comment: 10 pages including 1 figure, AASTeX, accepted by Ap
The Heumann-Hotzel model for aging revisited
Since its proposition in 1995, the Heumann-Hotzel model has remained as an
obscure model of biological aging. The main arguments used against it were its
apparent inability to describe populations with many age intervals and its
failure to prevent a population extinction when only deleterious mutations are
present. We find that with a simple and minor change in the model these
difficulties can be surmounted. Our numerical simulations show a plethora of
interesting features: the catastrophic senescence, the Gompertz law and that
postponing the reproduction increases the survival probability, as has already
been experimentally confirmed for the Drosophila fly.Comment: 11 pages, 5 figures, to be published in Phys. Rev.
Synthesis, characterisation and study of magnetocaloric effects (enhanced and reduced) in manganate perovskites.
Time evolution of the Partridge-Barton Model
The time evolution of the Partridge-Barton model in the presence of the
pleiotropic constraint and deleterious somatic mutations is exactly solved for
arbitrary fecundity in the context of a matricial formalism. Analytical
expressions for the time dependence of the mean survival probabilities are
derived. Using the fact that the asymptotic behavior for large time is
controlled by the largest matrix eigenvalue, we obtain the steady state values
for the mean survival probabilities and the Malthusian growth exponent. The
mean age of the population exhibits a power law decayment. Some Monte
Carlo simulations were also performed and they corroborated our theoretical
results.Comment: 10 pages, Latex, 1 postscript figure, published in Phys. Rev. E 61,
5664 (2000
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Evolution of the eyes of vipers with and without infrared-sensing pit organs
We examined lens and brille transmittance, photoreceptors, visual pigments, and visual opsin gene sequences of viperid snakes with and without infrared-sensing pit organs. Ocular media transmittance is high in both groups. Contrary to previous reports, small as well as large single cones occur in pit vipers. Non-pit vipers differ from pit vipers in having a twotiered retina, but few taxa have been examined for this poorly understood feature. All vipers sampled express rh1, sws1 and lws visual opsin genes. Opsin spectral tuning varies but not in accordance with the presence/absence of pit organs, and not always as predicted from gene sequences. The visual opsin genes were generally under purifying selection, with positive selection at spectral tuning amino acids in RH1 and SWS1 opsins, and at retinal pocket stabilization sites in RH1 or LWS (and without substantial differences between pit and nonpit vipers). Lack of evidence for sensory trade-off between viperid eyes (in the aspects examined) and pit organs might be explained by the high degree of neural integration of vision and infrared detection; the latter representing an elaboration of an existing sense with addition of a novel sense organ, rather than involving the evolution of a wholly novel sensory system
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