100 research outputs found

    GEOPHYSICAL INVESTIGATIONS OF THREE SITES WITHIN THE KNIFE RIVER INDIAN VILLAGES NATIONAL HISTORIC SITE, MERCER COUNTY, NORTH DAKOTA

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    The National Park Service’s Midwest Archeological Center staff and instructors and participants of the 2010 NPS archeological prospection workshop, along with students from the University of North Dakota’s 2010 fieldschool conducted geophysical investigations at three sites within Knife River Indian Villages National Historic Site in Mercer County, North Dakota. The geophysical investigations were conducted between May 10 and May 29, 2010. The investigations at the Elbee site, 32ME408, and Site 32ME2377 were requested by the KNRI superintendent as part of the compliance activities related to the erosion of the Knife River bank in the vicinity of the two sites. The geophysical investigations at the Taylor Bluff site, 32ME366, were conducted as part of the field exercises associated with the twentieth annual NPS archeological prospection workshop. The geophysical survey at the Elbee site included a resistance survey with a resistance meter and twin-probe array, a limited magnetic survey with a dual fluxgate gradiometer, and the re-analysis of the 2002 and 2006 magnetic data from the site. The geophysical survey at Site 32ME2377 included a resistance survey with a resistance meter and twin probe array and a magnetic survey with a single fluxgate gradiometer. Primary data collected at the Taylor Bluff site during the workshop included a ground- penetrating radar survey with a 400 mHz antenna and a magnetic survey with a dual fluxgate gradiometer. The geophysical surveys were conducted in order to identify buried archeological remains in the vicinity of the Knife River bank at the Elbee site and Site 32ME2377. The survey results provide a baseline of archeological geophysical data for a data recovery project by the University of North Dakota’s archeological fieldschool. The survey data from Sites 32ME366, 32ME407, and 32ME2377 provide subsurface information for future park planning activities. The geophysical data also provide information on the potential damage to the archeological resources from the continued erosion of the Knife River bank. The geophysical surveys identified numerous buried archeological remains associated with the prehistoric human occupation of the Elbee site, the historic Native American occupation of the Taylor Bluff site, and more recent historic farming and modern NPS activities at all three sites. The combined total area investigated by the geophysical survey in the three KNRI geophysical project areas was 17,086 m2 or 4.22 acres. The Elbee site and the Taylor Bluff site were recommended as eligible for listing on the National Register of Historic Places while Site 32ME2377 was recommended as not eligible

    2009 Archaeological Investigations at the Walters, Beedle, and Lyon Lots, Lincoln Home National Historic Site

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    Established in 1971, the Lincoln Home National Historic Site (LIHO) commemorates the life of the 16th President of the United States. The park contains the neighborhood where Abraham Lincoln spent most of his adult life in Springfield, Illinois (Townsend 2008:76-149). The Park consists of a four-block historic neighborhood, which is partly restored to the year of Abraham Lincoln’s election as President. The centerpiece of the park consists of the restored house where Lincoln’s family lived from 1844 to 1861, when he became the 16th President of the United States

    The Concise Guide to PHARMACOLOGY 2015/16:Ligand-gated ion channels

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    The Concise Guide to PHARMACOLOGY 2015/16 provides concise overviews of the key properties of over 1750 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. The full contents can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.13349/full. Ligand-gated ion channels are one of the eight major pharmacological targets into which the Guide is divided, with the others being: ligand-gated ion channels, voltage-gated ion channels, other ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The Concise Guide is published in landscape format in order to facilitate comparison of related targets. It is a condensed version of material contemporary to late 2015, which is presented in greater detail and constantly updated on the website www.guidetopharmacology.org, superseding data presented in the previous Guides to Receptors & Channels and the Concise Guide to PHARMACOLOGY 2013/14. It is produced in conjunction with NC-IUPHAR and provides the official IUPHAR classification and nomenclature for human drug targets, where appropriate. It consolidates information previously curated and displayed separately in IUPHAR-DB and GRAC and provides a permanent, citable, point-in-time record that will survive database updates

    The Concise Guide to PHARMACOLOGY 2015/16:Enzymes

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    The Concise Guide to PHARMACOLOGY 2015/16 provides concise overviews of the key properties of over 1750 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. The full contents can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.13354/full. G protein-coupled receptors are one of the eight major pharmacological targets into which the Guide is divided, with the others being: G protein-coupled receptors, ligand-gated ion channels, voltage-gated ion channels, other ion channels, nuclear hormone receptors, catalytic receptors and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The Concise Guide is published in landscape format in order to facilitate comparison of related targets. It is a condensed version of material contemporary to late 2015, which is presented in greater detail and constantly updated on the website www.guidetopharmacology.org, superseding data presented in the previous Guides to Receptors & Channels and the Concise Guide to PHARMACOLOGY 2013/14. It is produced in conjunction with NC-IUPHAR and provides the official IUPHAR classification and nomenclature for human drug targets, where appropriate. It consolidates information previously curated and displayed separately in IUPHAR-DB and GRAC and provides a permanent, citable, point-in-time record that will survive database updates

    The Concise Guide to PHARMACOLOGY 2015/16:Transporters

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    The Concise Guide to PHARMACOLOGY 2015/16 provides concise overviews of the key properties of over 1750 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. The full contents can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.13355/full. G protein-coupled receptors are one of the eight major pharmacological targets into which the Guide is divided, with the others being: G protein-coupled receptors, ligand-gated ion channels, voltage-gated ion channels, other ion channels, nuclear hormone receptors, catalytic receptors and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The Concise Guide is published in landscape format in order to facilitate comparison of related targets. It is a condensed version of material contemporary to late 2015, which is presented in greater detail and constantly updated on the website www.guidetopharmacology.org, superseding data presented in the previous Guides to Receptors & Channels and the Concise Guide to PHARMACOLOGY 2013/14. It is produced in conjunction with NC-IUPHAR and provides the official IUPHAR classification and nomenclature for human drug targets, where appropriate. It consolidates information previously curated and displayed separately in IUPHAR-DB and GRAC and provides a permanent, citable, point-in-time record that will survive database updates

    The Concise Guide to PHARMACOLOGY 2015/16:Nuclear hormone receptors

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    The Concise Guide to PHARMACOLOGY 2015/16 provides concise overviews of the key properties of over 1750 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. The full contents can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.13352/full. Nuclear hormone receptors are one of the eight major pharmacological targets into which the Guide is divided, with the others being: G protein-coupled receptors, ligand-gated ion channels, voltage-gated ion channels, other ion channels, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The Concise Guide is published in landscape format in order to facilitate comparison of related targets. It is a condensed version of material contemporary to late 2015, which is presented in greater detail and constantly updated on the website www.guidetopharmacology.org, superseding data presented in the previous Guides to Receptors & Channels and the Concise Guide to PHARMACOLOGY 2013/14. It is produced in conjunction with NC-IUPHAR and provides the official IUPHAR classification and nomenclature for human drug targets, where appropriate. It consolidates information previously curated and displayed separately in IUPHAR-DB and GRAC and provides a permanent, citable, point-in-time record that will survive database updates

    The Concise Guide to PHARMACOLOGY 2013/14: overview.

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    The Concise Guide to PHARMACOLOGY 2013/14 provides concise overviews of the key properties of over 2000 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties from the IUPHAR database. The full contents can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.12444/full. This compilation of the major pharmacological targets is divided into seven areas of focus: G protein-coupled receptors, ligand-gated ion channels, ion channels, catalytic receptors, nuclear hormone receptors, transporters and enzymes. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. A new landscape format has easy to use tables comparing related targets. It is a condensed version of material contemporary to late 2013, which is presented in greater detail and constantly updated on the website www.guidetopharmacology.org, superseding data presented in previous Guides to Receptors & Channels. It is produced in conjunction with NC-IUPHAR and provides the official IUPHAR classification and nomenclature for human drug targets, where appropriate. It consolidates information previously curated and displayed separately in IUPHAR-DB and GRAC and provides a permanent, citable, point-in-time record that will survive database updates

    2009 Archaeological Investigations at the Walters, Beedle, and Lyon Lots, Lincoln Home National Historic Site

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    Established in 1971, the Lincoln Home National Historic Site (LIHO) commemorates the life of the 16th President of the United States. The park contains the neighborhood where Abraham Lincoln spent most of his adult life in Springfield, Illinois (Townsend 2008:76-149). The Park consists of a four-block historic neighborhood, which is partly restored to the year of Abraham Lincoln’s election as President. The centerpiece of the park consists of the restored house where Lincoln’s family lived from 1844 to 1861, when he became the 16th President of the United States
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