Probing the lightest new gauge boson BHB_H in the littlest Higgs model via the processes γγ→ffˉBH\gamma\gamma \to f\bar{f}B_H at the ILC

The neutral gauge boson $B_H$ with the mass of hundreds GeV, is the lightest particle predicted by the littlest Higgs(LH) model, and such particle should be the first signal of the LH model at the planed ILC if it exists indeed. In this paper, we study some processes of the $B_H$ production associated with the fermion pair at the ILC, i.e., $\gamma\gamma\to f\bar{f}B_{H}$. The studies show that the most promising processes to detect $B_H$ among $\gamma\gamma\to f\bar{f}B_{H}$ are $\gamma\gamma\to l'^+l'^-B_{H}(l'=e,\mu)$, and they can produce the sufficient signals in most parameter space preferred by the electroweak precision data at the ILC. On the other hand, the signal produced via the certain $B_H$ decay modes is typical and such signal can be easily identified from the SM background. Therefore, $B_H$, the lightest gauge boson in the LH model would be detectable at the photon collider realized at the ILC.Comment: 12 pages, 4 figure

The production of the new gauge boson BHB_{H} via e−γe^{-}\gamma collision in the littlest Higgs model

The new lightest gauge boson $B_H$ with mass of a few hundred GeV is predicted in the littlest Higgs model. $B_H$ should be accessible in the planed ILC and the observation of such particle can strongly support the littlest Higgs model. The realization of $\gamma\gamma$ and $e\gamma$ collision will open a wider window to probe $B_H$. In this paper, we study the new gauge boson $B_{H}$ production processes $e^{-}\gamma\to e^{-}\gamma B_{H}$ and $e^{-}\gamma\to e^{-}Z B_{H}$ at the ILC. Our results show that the production cross section of the process $e^{-}\gamma\to e^{-}Z B_{H}$ is less than one fb in the most parameter spaces while the production cross section of the process $e^{-}\gamma\to e^{-}\gamma B_{H}$ can reach the level of tens fb and even hundreds of fb in the sizable parameter spaces allowed by the electroweak precision data. With the high luminosity, the sufficient typical signals could be produced, specially via $e^{-}\gamma\to e^{-}\gamma B_{H}$. Because the final electron and photon beams can be easily identified and the signal can be easily distinguished from the background produced by $Z$ and $H$ decaying, $B_H$ should be detectable via $e\gamma$ collision at the ILC. Therefore, the processes $e^{-}\gamma\to e^{-}\gamma B_{H}$ and $e^{-}\gamma\to e^{-}Z B_{H}$ provide a useful way to detect $B_{H}$ and test the littlest Higgs model.Comment: 15 pages, 3 figures. Some typos have been corrected, we have added some new references, and there are also some changes in equation 1

Xanthones and sesquiterpene derivatives from a marine-derived fungus Scopulariopsis sp.

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Highly-Sensitive Thin Film THz Detector Based on Edge Metal-Semiconductor-Metal Junction

Terahertz (THz) detectors have been extensively studied for various applications such as security, wireless communication, and medical imaging. In case of metal-insulator-metal (MIM) tunnel junction THz detector, a small junction area is desirable because the detector response time can be shortened by reducing it. An edge metal-semiconductor-metal (EMSM) junction has been developed with a small junction area controlled precisely by the thicknesses of metal and semiconductor films. The voltage response of the EMSM THz detector shows the clear dependence on the polarization angle of incident THz wave and the responsivity is found to be very high (similar to 2,169 V/W) at 0.4 THz without any antenna and signal amplifier. The EMSM junction structure can be a new and efficient way of fabricating the nonlinear device THz detector with high cut-off frequency relying on extremely small junction area

A Genome-Wide Association Study Identifies Novel Alleles Associated with Hair Color and Skin Pigmentation

We conducted a multi-stage genome-wide association study of natural hair color in more than 10,000 men and women of European ancestry from the United States and Australia. An initial analysis of 528,173 single nucleotide polymorphisms (SNPs) genotyped on 2,287 women identified IRF4 and SLC24A4 as loci highly associated with hair color, along with three other regions encompassing known pigmentation genes. We confirmed these associations in 7,028 individuals from three additional studies. Across these four studies, SLC24A4 rs12896399 and IRF4 rs12203592 showed strong associations with hair color, with p = 6.0×10−62 and p = 7.46×10−127, respectively. The IRF4 SNP was also associated with skin color (p = 6.2×10−14), eye color (p = 6.1×10−13), and skin tanning response to sunlight (p = 3.9×10−89). A multivariable analysis pooling data from the initial GWAS and an additional 1,440 individuals suggested that the association between rs12203592 and hair color was independent of rs1540771, a SNP between the IRF4 and EXOC2 genes previously found to be associated with hair color. After adjustment for rs12203592, the association between rs1540771 and hair color was not significant (p = 0.52). One variant in the MATP gene was associated with hair color. A variant in the HERC2 gene upstream of the OCA2 gene showed the strongest and independent association with hair color compared with other SNPs in this region, including three previously reported SNPs. The signals detected in a region around the MC1R gene were explained by MC1R red hair color alleles. Our results suggest that the IRF4 and SLC24A4 loci are associated with human hair color and skin pigmentation

The Reproducibility of Lists of Differentially Expressed Genes in Microarray Studies

Reproducibility is a fundamental requirement in scientific experiments and clinical contexts. Recent publications raise concerns about the reliability of microarray technology because of the apparent lack of agreement between lists of differentially expressed genes (DEGs). In this study we demonstrate that (1) such discordance may stem from ranking and selecting DEGs solely by statistical significance (P) derived from widely used simple t-tests; (2) when fold change (FC) is used as the ranking criterion, the lists become much more reproducible, especially when fewer genes are selected; and (3) the instability of short DEG lists based on P cutoffs is an expected mathematical consequence of the high variability of the t-values. We recommend the use of FC ranking plus a non-stringent P cutoff as a baseline practice in order to generate more reproducible DEG lists. The FC criterion enhances reproducibility while the P criterion balances sensitivity and specificity

An Updated Search of Steady TeV γ−\gamma-Ray Point Sources in Northern Hemisphere Using the Tibet Air Shower Array

Using the data taken from Tibet II High Density (HD) Array (1997 February-1999 September) and Tibet-III array (1999 November-2005 November), our previous northern sky survey for TeV $\gamma-$ray point sources has now been updated by a factor of 2.8 improved statistics. From $0.0^{\circ}$ to $60.0^{\circ}$ in declination (Dec) range, no new TeV $\gamma-$ray point sources with sufficiently high significance were identified while the well-known Crab Nebula and Mrk421 remain to be the brightest TeV $\gamma-$ray sources within the field of view of the Tibet air shower array. Based on the currently available data and at the 90% confidence level (C.L.), the flux upper limits for different power law index assumption are re-derived, which are approximately improved by 1.7 times as compared with our previous reported limits.Comment: This paper has been accepted by hepn