2,029 research outputs found
Local Group dSph radio survey with ATCA (III): Constraints on Particle Dark Matter
We performed a deep search for radio synchrotron emissions induced by weakly
interacting massive particles (WIMPs) annihilation or decay in six dwarf
spheroidal (dSph) galaxies of the Local Group. Observations were conducted with
the Australia Telescope Compact Array (ATCA) at 16 cm wavelength, with an rms
sensitivity better than 0.05 mJy/beam in each field. In this work, we first
discuss the uncertainties associated with the modeling of the expected signal,
such as the shape of the dark matter (DM) profile and the dSph magnetic
properties. We then investigate the possibility that point-sources detected in
the proximity of the dSph optical center might be due to the emission from a DM
cuspy profile. No evidence for an extended emission over a size of few arcmin
(which is the DM halo size) has been detected. We present the associated bounds
on the WIMP parameter space for different annihilation/decay final states and
for different astrophysical assumptions. If the confinement of electrons and
positrons in the dSph is such that the majority of their power is radiated
within the dSph region, we obtain constraints on the WIMP annihilation rate
which are well below the thermal value for masses up to few TeV. On the other
hand, for conservative assumptions on the dSph magnetic properties, the bounds
can be dramatically relaxed. We show however that, within the next 10 years and
regardless of the astrophysical assumptions, it will be possible to
progressively close in on the full parameter space of WIMPs by searching for
radio signals in dSphs with SKA and its precursors.Comment: 17 pages, 6 figure panels. Companion papers: arXiv:1407.5479 and
arXiv:1407.5482. v3: minor revision, matches published versio
Patient-Reported Outcomes Measurement Information System physical function correlates with Toronto Extremity Salvage Score in an orthopaedic oncology population
Background: The National Institute of Health\u27s Patient-Reported Outcomes Measurement Information System (PROMIS) uses computerised-adaptive testing to reduce survey burden and improve sensitivity. PROMIS is being used across medical and surgical disciplines but has not been studied in orthopaedic oncology.
Questions/purposes: The aim of the study was to compare PROMIS measures with upper extremity (UE) and lower extremity (LE) Toronto Extremity Salvage Score (TESS) by assessing the following: (1) responder burden, (2) correlation between scores and (3) floor/ceiling effects.
Patients and methods: This cross-sectional trial analysed all 97 adult patients treated surgically for a bone or soft tissue tumour at a tertiary institution between November 2015 and March 2016. TESS (UE or LE) and PROMIS (Physical Function, Pain Interference and Depression) surveys were administered preoperatively. Pearson correlations between each PROMIS domain and TESS were calculated, as were floor/ceiling effects of each outcome measure.
Results: (1) Completion of three PROMIS questionnaires required a mean total of 16.8 (+/- 5.8 standard deviation) questions, compared with 31 and 32 questions for the LE and UE TESS questionnaires, respectively. (2) The PROMIS Physical Function scores demonstrated a strong positive correlation with the LE TESS (r = 0.84; 95% confidence interval [CI], 0.72-0.91; p \u3c 0.001) and moderate positive correlation with the UE TESS (r = 0.64; 95% CI, 0.34-0.83; p = 0.055). The PROMIS Depression scores demonstrated a weak negative correlation with both the LE TESS (r = -0.38; 95% CI, -0.61 to -0.10; p = 0.010) and with UE TESS (r = -0.38; 95% CI, -0.67 to -0.01; p = 0.055). The PROMIS Pain Interference scores demonstrated a strong negative correlation with the LE TESS (r = -0.71; 95% CI, -0.83 to -0.52; p \u3c 0.001) and a moderate negative correlation with the UE TESS (r = -0.62; 95% CI, -0.81 to -0.30; p = 0.001). (3) The UE TESS had a range of scores from 16 to 100 with a 27% ceiling effect and no floor effect, and the LE TESS had a range from 10 to 98 with no floor or ceiling effect. There was no floor or ceiling effect for any PROMIS measures.
Conclusions: In an orthopaedic oncology population, the PROMIS Physical Function and Pain Interference scores correlate with the TESS and have the benefit of reduced survey burden and ceiling effect. The PROMIS Depression scores may provide additional information regarding patient outcomes not captured by the TESS.
Level of Evidence: Level III.
The translational potential of this article: Patient reported outcome measures asses patients\u27 symptoms, function and health-related quality of life and are designed to capture more clinical information than can be gathered by objective medial testing alone. As reimbursements and the understanding of patient outcomes are becoming tied to performance on PROMIS measures, it is an important step to establish how PROMIS measures correlate and compare to traditional legacy measures
A Dark Matter Candidate from an Extra (Non-Universal) Dimension
We show that a recently constructed five-dimensional (5D) model with
gauge-Higgs unification and explicit Lorentz symmetry breaking in the bulk,
provides a natural dark matter candidate. This is the lightest Kaluza-Klein
particle odd under a certain discrete Z_2 symmetry, which has been introduced
to improve the naturalness of the model, and resembles KK-parity but is less
constraining.
The dark matter candidate is the first KK mode of a 5D gauge field and
electroweak bounds force its mass above the TeV scale. Its pair annihilation
rate is too small to guarantee the correct relic abundance; however
coannihilations with colored particles greatly enhance the effective
annihilation rate, leading to realistic relic densities.Comment: 26 pages, 10 figures; v2: fig.1 corrected, one reference and some
comments added, conclusions unchanged. Version to appear in JHE
Safety of overlapping inpatient orthopaedic surgery: A multicenter study
BackgroundAlthough overlapping surgery is used to maximize efficiency, more empirical data are needed to guide patient safety. We conducted a retrospective cohort study to evaluate the safety of overlapping inpatient orthopaedic surgery, as judged by the occurrence of perioperative complications.MethodsAll inpatient orthopaedic surgical procedures performed at 5 academic institutions from January 1, 2015, to December 31, 2015, were included. Overlapping surgery was defined as 2 skin incisions open simultaneously for 1 surgeon. In comparing patients who underwent overlapping surgery with those who underwent non-overlapping surgery, the primary outcome was the occurrence of a perioperative complication within 30 days of the surgical procedure, and secondary outcomes included all-cause 30-day readmission, length of stay, and mortality. To determine if there was an association between overlapping surgery and a perioperative complication, we tested for non-inferiority of overlapping surgery, assuming a null hypothesis of an increased risk of 50%. We used an inverse probability of treatment weighted regression model adjusted for institution, procedure type, demographic characteristics (age, sex, race, comorbidities), admission type, admission severity of illness, and clustering by surgeon.ResultsAmong 14,135 cases, the frequency of overlapping surgery was 40%. The frequencies of perioperative complications were 1% in the overlapping surgery group and 2% in the non-overlapping surgery group. The overlapping surgery group was non-inferior to the non-overlapping surgery group (odds ratio [OR], 0.61 [90% confidence interval (CI), 0.45 to 0.83]; p < 0.001), with reduced odds of perioperative complications (OR, 0.61 [95% CI, 0.43 to 0.88]; p = 0.009). For secondary outcomes, there was a significantly lower chance of all-cause 30-day readmission in the overlapping surgery group (OR, 0.67 [95% CI, 0.52 to 0.87]; p = 0.003) and shorter length of stay (e, 0.94 [95% CI, 0.89 to 0.99]; p = 0.012). There was no difference in mortality.ConclusionsOur results suggest that overlapping inpatient orthopaedic surgery does not introduce additional perioperative risk for the complications that we evaluated. The suitability of this practice should be determined by individual surgeons on a case-by-case basis with appropriate informed consent.Level of evidenceTherapeutic Level III. See Instructions for Authors for a complete description of levels of evidence
VLBA determination of the distance to nearby star-forming regions I. The distance to T Tauri with 0.4% accuracy
In this article, we present the results of a series of twelve 3.6-cm radio
continuum observations of T Tau Sb, one of the companions of the famous young
stellar object T Tauri. The data were collected roughly every two months
between September 2003 and July 2005 with the Very Long Baseline Array (VLBA).
Thanks to the remarkably accurate astrometry delivered by the VLBA, the
absolute position of T Tau Sb could be measured with a precision typically
better than about 100 micro-arcseconds at each of the twelve observed epochs.
The trajectory of T Tau Sb on the plane of the sky could, therefore, be traced
very precisely, and modeled as the superposition of the trigonometric parallax
of the source and an accelerated proper motion. The best fit yields a distance
to T Tau Sb of 147.6 +/- 0.6 pc. The observed positions of T Tau Sb are in good
agreement with recent infrared measurements, but seem to favor a somewhat
longer orbital period than that recently reported by Duchene et al. (2006) for
the T Tau Sa/T Tau Sb system.Comment: 24 pages, 3 pages, AASTEX format, accepted for publication in Ap
Comportamento da Macrofauna edáfica em diferentes modelos de arborização de cafeeiro Robusta (Coffea canephora) em Rondônia.
O levantamento da fauna edáfica do solo é uma forma indicada de avaliar a viabilidade em função do manejo deste tipo de sistema. O objetivo deste trabalho foi fazer um levantamento da ocorrência da macrofauna do solo em 05 (dez) propriedades cultivadas com o café Robusta (Coffea canephora) arborizado no município de Rolim de Moura, localizado na região da Zona da Mata/RO em duas épocas diferentes. Na época chuvosa e seca, as Ordens com maiores frequência de ocorrência foram Hymenoptera, Araneae, Coleoptera, Dermaptera, Orthoptera, Isoptera, Acari, Lithobiomorpha, Diptera, Hemiptera. Através do índice de diversidade de Shannon identificou-se propriedades com maior estabilidade, principalmente quando houve maior diversidade de espécies florestais nos SAFs. O manejo dos SAFs, o clima, a diversidade de espécies florestais e o tamanho das áreas amostradas possivelmente influenciam a diversidade de Ordens da macrofauna
Study of damage control systems for space station
Damage control systems for detecting and locating overboard and onboard leak and damage modes on space station
Participatory yield assessment of climbing and bush beans under different management options in Malawi
Caracterização de dez áreas com café conilon arborizado na Zona da Mata de Rondônia.
A presente pesquisa faz parte de um projeto maior de manejo da lavoura cafeeira arborizada e objetivou identificar as principais espécies utilizadas na arborização de áreas com cafeeiro Robusta nos município de Rolim de Moura e Nova Brasilândia do Oeste. A pesquisa foi desenvolvida em dez propriedades, cinco por município, e constou da aplicação de um questionário sócio-econômico, no qual foram levantadas a área total de cada propriedade, área com café Robusta, área com a(s) espécie(s) arborizadora, número de plantas, produtividade e idade do cafeeiro. Em Rolim de Moura a área total das propriedades avaliadas com cafeeiro Robusta arborizado é de 7,9 ha, a produtividade média varia de 10 a 100 sacas/ha, a idade do cafeeiro varia de 5 a 15 anos. No município de Nova Brasilândia a área total com café nas propriedades analisadas é de 15, 58ha, produtividade variando de 9 a 85 sacas/ha, a idade do cafeeiro varia de 5 a 21 anos
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