2,448 research outputs found
Commentary on 'Improving the seasonal cycle and interannual variations of biomass burning aerosol sources' by Generoso et al.
In a recent published paper, Generoso et al. (2003) describe a method for improving the spatial and temporal distribution of pyrogenic aerosol emission inventories. In the course of their analysis, the authors note several significant discrepancies in the seasonality of burning as observed by the Visible and Infrared Scanner (VIRS) and four other biomass burning data sets derived from satellite observations. In this commentary we explain the source of these discrepancies and clarify the origin of the VIRS observations that were used by Generoso et al
Single-center experience in the treatment of visceral artery aneurysms
Background: Visceral artery aneurysms (VAAs), although rare, represent a life-threatening disease with high mortality rates. With the more frequent use of diagnostic tests, there has been an incidental detection of these lesions which are mostly asymptomatic. It follows that surgeons are increasingly called to decide on the most appropriate management of VAAs between an open surgical or endovascular approach and among the different endovascular options currently available. The aim of this retrospective study was to evaluate the results of open surgery and interventional endovascular strategies of visceral artery aneurysms with respect to technical success, therapy-associated complications, and postinterventional follow-up in the elective and emergency situation. Methods: From January 1992 to January 2017, 125 open surgical or endovascular interventions for VAA were performed at our institution. Once the VAA was diagnosed and the indication for treatment was assessed, the preoperative diagnostic work-up consisted of contrast computed tomography (CT) or magnetic resonance imaging (MRI) and, in some patients, digital subtraction angiography. Follow-up included clinical and duplex ultrasound scan (DUS) and contrast-enhanced ultrasound to assess the treated vessel patency and organ perfusion after 1, 6, and 12 months, and yearly thereafter. CT or MRI controls were also performed at 1 year of follow-up and only when DUS was not diagnostic or showed a complication thereafter. After the first 5 years of follow-up, the status of the patient was obtained by a structured telephone survey. Results: The treatment option was endovascular in 56 of 125 cases (44.8%). Technical success was 98.3%. In one case, the procedure was interrupted for the extensive dissection of the afferent vessel. Twenty-six patients were treated by coil embolization while 29 with covered stenting. The endovascular approach was in emergency in two cases (3.6%). In the endovascular group, mortality was nil. Complications occurred in 5 cases (8.9%): 1 subacute intestinal ischemia caused by superior mesenteric artery dissection, 2 aneurysm reperfusion, 1 stent thrombosis, and 1 massive splenic hematoma. In 69 (55.2%) cases, surgical treatment was preferred, with 24 VAA resections and 45 arterial reconstructions. In 20 cases (29%), open surgery was performed in emergency conditions. In the surgical group, 8 emergency patients (40%) died intraoperatively. The mortality after elective surgical interventions was nil. Complications after surgery were 4 graft late thrombosis (5.8%): asymptomatic in three cases and requiring splenectomy in one. Conclusions: There is no overall consensus regarding the indications for treatment of VAA. Currently in emergent setting, the endovascular approach should be considered as the first choice because of its reduced invasiveness, faster way to access and bleeding control; this accounts for the lower morality of the interventional therapy than open surgery. Endovascular approach is effective for elective repair of VAAs, but procedure-related complications may occur in a not negligible number of patients. Given comparable mortality rates and low procedure-related complication rate, surgical approach still has space in the elective management of VAAs, especially for aneurysms unsuitable or challenging for the endovascular option in patients with low surgical risk. The size, location, and morphology of VAAs, systemic or local comorbidities, and specific anatomical situations such as previous abdominal surgery should dictate treatment choice
Valutazione della capacitĂ di rientro alla base di un elicottero in presenza di danno balistico ad un albero di trasmissione della linea rotore di coda
Nella progettazione di un elicottero militare, destinato ad operare a bassa quota e in ambiente ostile, il danneggiamento di componenti critici, conseguente ad impatto balistico, riveste un ruolo primario nella valutazione delle possibilità di sopravvivenza dell’intera macchina. In questo articolo è quindi proposto uno studio sperimentale, suddiviso in diverse fasi, riguardante la verifica della capacità di un elicottero di portare a termine una missione di rientro alla base a potenza ridotta e in presenza di danneggiamento balistico ad un albero di trasmissione della linea rotore di coda. Il lavoro ha richiesto dapprima l’esecuzione, su esemplari del componente in esame, di prove sperimentali di impatto balistico, condotte utilizzando un proiettile calibro 7.62 NATO. Successivamente su ciascun albero danneggiato sono state eseguite prove torsionali statiche ed a fatica, il cui scopo è stato verificare la resistenza residua del componente all’applicazione di opportuni carichi rappresentativi delle sollecitazioni riscontrate durante la missione di rientro
Valutazione della capacitĂ di rientro alla base di un elicottero in presenza di danno balistico ad un albero di trasmissione della linea rotore di coda
Nella progettazione di un elicottero militare, destinato ad operare a bassa quota e in ambienteostile, il danneggiamento di componenti critici, conseguente ad impatto balistico, riveste un ruolo primario nellavalutazione delle possibilità di sopravvivenza dell’intera macchina. In questo articolo è quindi proposto unostudio sperimentale, suddiviso in diverse fasi, riguardante la verifica della capacità di un elicottero di portare atermine una missione di rientro alla base a potenza ridotta e in presenza di danneggiamento balistico ad unalbero di trasmissione della linea rotore di coda.Il lavoro ha richiesto dapprima l’esecuzione, su esemplari del componente in esame, di prove sperimentali diimpatto balistico, condotte utilizzando un proiettile calibro 7.62 NATO. Successivamente su ciascun alberodanneggiato sono state eseguite prove torsionali statiche ed a fatica, il cui scopo è stato verificare la resistenzaresidua del componente all’applicazione di opportuni carichi rappresentativi delle sollecitazioni riscontratedurante la missione di rientro
Perioperative hemodynamic goal-directed therapy and mortality: a systematic review and meta-analysis with meta-regression
INTRODUCTION: Recent data found that perioperative goal directed therapy (GDT) was effective only in higher control mortality rates (> 20%) with a relatively high heterogeneity that limited the strength of evidence. The aim of the present meta-analysis was to clearly understand which high risk patients may benefit of GDT.EVIDENCE ACQUISITION: Systematic review of randomized controlled trials with meta-analyses, including a meta-regression technique. MEDLINE, EMBASE, and The Cochrane Library databases were searched (1980-January 2015). Trials enrolling adult surgical patients and comparing the effects of GDT versus standard hemodynamic therapy were considered. The primary outcome measure was mortality. Data synthesis was obtained by using Odds Ratio (OR) with 95% confidence interval (CI) by random-effects model.EVIDENCE SYNTHESIS: Fifty eight studies met the inclusion criteria (8171 participants). Pooled OR for mortality was 0.70 (95% CI 0.56-0.88, P= 0.002, no statistical heterogeneity). GDT significantly reduced mortality when it is > 10% in control group (OR 0.43, 95% CI 0.30-0.61, P< 0.00001). The meta-regression model showed that the cut off of 10% of mortality rate in control group significantly differentiates 43 studies from the other 15, with a regression coefficient b of -0.033 and a P value of 0.0001. The significant effect of GDT was driven by high risk of bias studies (OR 0.48, 95% CI 0.34-0.67, P< 0.0001).CONCLUSIONS: The present meta-analysis, adopting the meta-regression technique, suggests that GDT significantly reduces mortality even when the event control rate is > 10%
Damage assessment of CFRP laminate plate subjected to close-range blast loading: hydrocode methodology validation and case study
Blast loading represents a critical damaging event in all structures. Although composite materials have been increasingly adopted in structural application, the effect of such dynamic loading event on composite structures is still to be evaluated in detail. This work defines a reliable numerical methodology to assess the damage occurring in carbon fiber reinforced polymer (CFRP) plate subjected to close-range blast loading. The numerical methodology is validated with a benchmark experiment found in literature and is employed to study in detail the damage mechanisms and eventual Fluid Structure Interaction (FSI) effects. The numerical analyses are carried out through a commercially available software package employing two methods, i.e., the ConWep and the hybrid coupled Eulerian-Lagrangia (CEL)-ConWep approaches, and the results from the simulations are compared with experimental evidence from the original work. The results show that (i) the hybrid approach seems to be a promising solution in terms of efficiency and accuracy in modelling blast events, (ii) the ConWep approach accurately reproduces experimental observations, even though such a method has strong limitations. (C) 2022 The Authors. Published by Elsevier B.V
Analysis of strain rate behavior of an Al 6061 T6 alloy
Abstract In order to simulate complex scenario like ballistic impact, correct material calibration is fundamental. The material in the area involved by impact can experience high deformation and damage in a very limited time. As a consequence dynamic tests on the materials are needed in order to calibrate constitutive law able to describe the material behavior in terms of hardening and in particular strain rate. According to the fact that no guidelines are available on testing methods, different types of testing techniques have been used to generate data under dynamic conditions. Several dynamic tests, are carried out on Al 6061 T6 specimens and the experimental data elaborated. The developed procedure is useful to take into account also the thermal phenomena generally affecting high strain-rate tests due to the adiabatic overheating related to the conversion of plastic work. The method presented requires strong effort both from experimental and numerical point of view; anyway it allows to precisely identifying the parameters of a material models. This could provide great advantages when high reliability of the material behavior is necessary
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