2,024 research outputs found
Normal-metal quasiparticle traps for superconducting qubits
The presence of quasiparticles in superconducting qubits emerges as an
intrinsic constraint on their coherence. While it is difficult to prevent the
generation of quasiparticles, keeping them away from active elements of the
qubit provides a viable way of improving the device performance. Here we
develop theoretically and validate experimentally a model for the effect of a
single small trap on the dynamics of the excess quasiparticles injected in a
transmon-type qubit. The model allows one to evaluate the time it takes to
evacuate the injected quasiparticles from the transmon as a function of trap
parameters. With the increase of the trap size, this time decreases
monotonically, saturating at the level determined by the quasiparticles
diffusion constant and the qubit geometry. We determine the characteristic trap
size needed for the relaxation time to approach that saturation value.Comment: 11 pages, 5 figure
Abundances in HD27411 and the helium problem in Am stars
We analyze a high-resolution spectrum of the A3m star HD27411. We compare
abundances derived from ATLAS9 model atmospheres with those using the more
computationally-intensive ATLAS12 code. We found very little differences in the
abundances, suggesting that ATLAS9 can be used for moderate chemical
peculiarity. Our abundances agree well with the predictions of diffusion
theory, though for some elements it was necessary to calculate line profiles in
non-thermodynamic equilibrium to obtain agreement. We investigate the effective
temperatures and luminosities of Am/Fm stars using synthetic Stromgren indices
derived from calculated spectra with the atmospheric abundances of HD27411. We
find that the effective temperatures of Am/Fm stars derived from Stromgren
photometry are reliable, but the luminosities are probably too low. Caution is
required when deriving the reddening of these stars owing to line blanketing
effects. A comparison of the relative proportions of pulsating and
non-pulsating Am stars with delta Scuti stars shows quite clearly that there is
no significant decrease of helium in the driving zone, contrary to current
models of diffusion.Comment: 10 pages, 8 figures, 6 tables, accepted for publication in MNRA
Pretubulysin derived probes as novel tools for monitoring the microtubule network via activity-based protein profiling and fluorescence microscopy
Microtubules (mt) are highly dynamic polymers composed of alpha- and beta-tubulin monomers that are present in all dividing and non-dividing cells. A broad variety of natural products exists that are known to interfere with the microtubule network, by either stabilizing or de-stabilizing these rope-like polymers. Among those tubulysins represent a new and potent class of cytostatic tetrapeptides originating from myxobacteria. Early studies suggested that tubulysins interact with the eukaryotic cytoskeleton by inhibition of tubulin polymerization with EC50 values in the picomolar range. Recently, pretubulysins have been described to retain the high tubulindegradation activity of their more complex tubulysin relatives and represent an easier synthetic target with an efficient synthesis already in place. Although tubulin has been suggested as the dedicated target of tubulysin a comprehensive molecular target analysis of pretubulysin in the context of the whole proteome has not been carried out so far. Here we utilize synthetic chemistry to develop two pretubulysin photoaffinity probes which were applied in cellular activity-based protein profiling and imaging studies in order to unravel and visualize dedicated targets.
Our results clearly show a remarkable selectivity of pretubulysin for beta-tubulin which we independently confirmed by a mass-spectrometry based proteomic profiling platform as well as by tubulin antibody based co-staining on intact cells
TurbuStat: Turbulence Statistics in Python
We present TurbuStat (v1.0): a Python package for computing turbulence
statistics in spectral-line data cubes. TurbuStat includes implementations of
fourteen methods for recovering turbulent properties from observational data.
Additional features of the software include: distance metrics for comparing two
data sets; a segmented linear model for fitting lines with a break-point; a
two-dimensional elliptical power-law model; multi-core fast-fourier-transform
support; a suite for producing simulated observations of fractional Brownian
Motion fields, including two-dimensional images and optically-thin HI data
cubes; and functions for creating realistic world coordinate system information
for synthetic observations. This paper summarizes the TurbuStat package and
provides representative examples using several different methods. TurbuStat is
an open-source package and we welcome community feedback and contributions.Comment: Accepted in AJ. 21 pages, 8 figure
Engagement to Enhance Community: An Example of Extension’s Land-Grant Mission in Action
Engagement is a foundational practice for the Extension systems of land-grant universities and is demonstrated through its’ work in partnership with individuals, organizations and communities. This article will share how an Extension-led effort, focused on an aspect of community development, integrated several components of engagement starting with the initial conversation through the evaluation process. Practitioner reflections on two examples that occurred in different states will highlight the processes and tools that helped nurture engagement between faculty and community and support the development of a sustainable and resilient community. The multi-state implementation will illustrate the unique depth and breadth of public participation that can be achieved when academic institutions are focused on engagement to strengthen communities
FACTORS DETERMINING STRUCTURED ACTIVITY PARTICIPATION IN RURAL YOUTH : INTERNAL CAPACITIES, MICROSYSTEM SUPPORT, AND CONSTRAINT NEGOTIATION
Rural youth often face challenges to recreation participation that differ from their urban counterparts. Fewer opportunities for exposure to positive adults, and a lack of resources and programs limit opportunities to positively impact youth in their free time. While these are commonly identified interpersonal and structural constraints, the research literature on adolescent intrapersonal constraints tends to focus on preferences or psychological variables related to aversion as opposed to limitations due to development. Resilience traits or protective factors can be thought of as internal capacities to support development and contribute to one's quality of life. The purpose of this study was to examine how the internal capacities of youth and the presence of external supports from parents and other adults predicted participation in high yield, structured recreation activities among rural youth. Secondary purposes of this study were to understand the constraints to participating in structured activities and identify the negotiation strategies youth use to initiate and continue participation in structured activities. Guided by Ecological Systems Theory (EST), the study examined relationships with parents and other adults through a concurrent mixed-model design using survey data and focus groups with youth aged 11-16 years. Findings support the proposition that the internal capacities of youth related positively to the availability of high expectations from and caring relationships with parents. Goals and aspirations of youth, an internal capacity, and high expectations from adults also predicted youth participation in structured activities. In focus groups, youth cited distance from opportunities and family obligations as the primary reasons for not participating in sports and after school activities. Constraint negotiation to initiate and continue activities came primarily from the availability of parental resources, making conscious choices to avoid boredom, and the influence and expectations of others. Recommendations for practice focuses on asset mapping and developing recreational programs housed at local community centers.Ă‚Â Ă‚Â M.S
Electron self-energy in A3C60 (A=K, Rb): Effects of t1u plasmon in GW approximation
The electron self-energy of the t1u states in A3C60 (A=K, Rb) is calculated
using the so-called GW approximation. The calculation is performed within a
model which considers the t1u charge carrier plasmon at 0.5 eV and takes into
account scattering of the electrons within the t1u band. A moderate reduction
(35 %) of the t1u band width is obtained.Comment: 4 pages, revtex, 1 figure more information at
http://www.mpi-stuttgart.mpg.de/dokumente/andersen/fullerene
Late stages of the evolution of A-type stars on the main sequence: comparison between observed chemical abundances and diffusion models for 8 Am stars of the Praesepe cluster
Aims. We aim to provide observational constraints on diffusion models that
predict peculiar chemical abundances in the atmospheres of Am stars. We also
intend to check if chemical peculiarities and slow rotation can be explained by
the presence of a weak magnetic field.
Methods. We have obtained high resolution, high signal-to-noise ratio spectra
of eight previously-classified Am stars, two normal A-type stars and one Blue
Straggler, considered to be members of the Praesepe cluster. For all of these
stars we have determined fundamental parameters and photospheric abundances for
a large number of chemical elements, with a higher precision than was ever
obtained before for this cluster. For seven of these stars we also obtained
spectra in circular polarization and applied the LSD technique to constrain the
longitudinal magnetic field.
Results. No magnetic field was detected in any of the analysed stars. HD
73666, a Blue Straggler previously considered as an Ap (Si) star, turns out to
have the abundances of a normal A-type star. Am classification is not confirmed
for HD 72942. For HD 73709 we have also calculated synthetic Delta-a photometry
that is in good agreement with the observations. There is a generally good
agreement between abundance predictions of diffusion models and values that we
have obtained for the remaining Am stars. However, the observed Na and S
abundances deviate from the predictions by 0.6 dex and >0.25 dex respectively.
Li appears to be overabundant in three stars of our sample.Comment: Accepted for publication on A&
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