21,860 research outputs found

    Anisotropic Transport Properties of Ferromagnetic-Superconducting Bilayers

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    We study the transport properties of vortex matter in a superconducting thin film separated by a thin insulator layer from a ferromagnetic layer. We assume an alternating stripe structure for both FM and SC layers as found in [7]. We calculate the periodic pinning force in the stripe structure resulting from a highly inhomogeneous distribution of the vortices and antivortices. We show that the transport properties in FM-SC bilayer are highly anisotropic. In the absence of random pinning it displays a finite resistance for the current perpendicular to stripes and is superconducting for the current parallel to stripes. The average vortex velocity, electric field due to the vortex motion, Josephson frequency and higher harmonics of the vortex oscillatory motion are calculated.Comment: 4 pages, 2figures, Submitted to PR

    Endoscopic endonasal management of recurrent petrous apex cholesterol granuloma.

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    Petrous apex cholesterol granulomas (PACG) are uncommon lesions. Recurrence following transcranial or endonasal approaches to aerate the cyst occurs in up to 60% of cases. We describe the technical nuances pertinent to the endonasal endoscopic management of a recurrent symptomatic PACG and review the literature. A 19-year-old woman presented with a recurrent right abducens nerve paresis. Four months prior, she underwent an endonasal transsphenoidal surgery (TSS) for drainage of a symptomatic PACG. Current imaging documented recurrence of the right PACG. Transsphenoidal and infrapetrous approaches were performed to obtain a wider bony opening along the petrous apex and drain the cyst. A Doyle splint was inserted into the cyst's cavity and extended out into the sphenoid, maintaining patency during the healing process. Three months after surgery, the splint was removed endoscopically, allowing visualization of a patent cylindrical communication between both aerated cavities. The patient remains symptom- and recurrence-free. Endoscopic endonasal surgery must be adapted to manage recurrent PACG. A TSS may not be sufficient. An infrapetrous approach with wider bony opening, extensive removal of the cyst's anterior wall, and use of a stent are indicated for the treatment of recurrent PACG and to prevent recurrences

    Split histidine kinases enable ultrasensitivity and bistability in two-component signaling networks

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    Bacteria sense and respond to their environment through signaling cascades generally referred to as two-component signaling networks. These networks comprise histidine kinases and their cognate response regulators. Histidine kinases have a number of biochemical activities: ATP binding, autophosphorylation, the ability to act as a phosphodonor for their response regulators, and in many cases the ability to catalyze the hydrolytic dephosphorylation of their response regulator. Here, we explore the functional role of “split kinases” where the ATP binding and phosphotransfer activities of a conventional histidine kinase are split onto two distinct proteins that form a complex. We find that this unusual configuration can enable ultrasensitivity and bistability in the signal-response relationship of the resulting system. These dynamics are displayed under a wide parameter range but only when specific biochemical requirements are met. We experimentally show that one of these requirements, namely segregation of the phosphatase activity predominantly onto the free form of one of the proteins making up the split kinase, is met in Rhodobacter sphaeroides. These findings indicate split kinases as a bacterial alternative for enabling ultrasensitivity and bistability in signaling networks. Genomic analyses reveal that up 1.7% of all identified histidine kinases have the potential to be split and bifunctional

    Flat-top oscillons in an expanding universe

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    Oscillons are extremely long lived, oscillatory, spatially localized field configurations that arise from generic initial conditions in a large number of non-linear field theories. With an eye towards their cosmological implications, we investigate their properties in an expanding universe. We (1) provide an analytic solution for one dimensional oscillons (for the models under consideration) and discuss their generalization to 3 dimensions, (2) discuss their stability against long wavelength perturbations and (3) estimate the effects of expansion on their shapes and life-times. In particular, we discuss a new, extended class of oscillons with surprisingly flat tops. We show that these flat topped oscillons are more robust against collapse instabilities in (3+1) dimensions than their usual counterparts. Unlike the solutions found in the small amplitude analysis, the width of these configurations is a non-monotonic function of their amplitudes.Comment: v2-matches version published in Phys. Rev D. Updated references and minor modification to section 4.

    Dissipation and coherent effects in narrow superconducting channels

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    We apply the time dependent Ginzburg-Landau equations (TDGL) to study small ac currents of frequency ω\omega in superconducting channels narrow on the scale of London penetration depth. We show that TDGL have tt-dependent and spatially uniform solutions that describe the order parameter with an oscillating part of the double frequency coexisting with an ac electric field. We evaluate the Ohmic losses (related neither to the flux flow nor to the phase slips) and show that the resistivity reduction on cooling through the critical temperature TcT_c should behave as (TcT)2/ω2(T_c-T)^2/\omega^2. If the channel is cut out of an anisotropic material in a direction other than the principal axes, the transverse phase difference and the Josephson voltage between the channel sides are generated.Comment: 5 pages, 1 figures, Accepted for publication in Phys. Rev.

    Problematika Penyelesaian Konflik Tanah Ulayat Masyarakat Adat di Kabupaten Kampar

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    Conflict of indigenous communal land Gunung Sahilan Village with one of the private firms, namely PT. RAPP concession due to industrial timber estates (HTI) PT. RAPP is above the communal land belonging to indigenous village Gunung Sahilan, therefore the public demand to restore the land, but the company could not meet the demands of society on the grounds that their land is State land and has been given permission by the Ministry of Forestry to manage the land The. This conflict continued and led to the clash between the two sides that led to as many as 15 injured people from the indigenous village of Gunung Sahilan, 14 people from the PT. RAPP and damage to the motorcycle belonging to indigenous village Gunung Sahilan 75 units. This clash ended peacefully with the agreement of both parties that the results of PT. RAPP bear all medical expenses of victims clashed and replace all damage to public vehicles damaged by the symbol would. PT. RAPP also be sanctioned for violating the indigenous customary law applicable by the villagers of Gunung Sahilan, given traditional sanctions in the form of 3 buffaloes, cows and money 3 helatan implementation of Rp. 30,000,000.This research was conducted in the village of Gunung Sahilan District of Gunung Sahilan Kampar district. This study aims to determine the problems of indigenous communal land conflicts in the village of Gunung Sahilan District of Gunung Sahilan Kampar District, and to determine how to resolve conflicts and obstacles to its completion. The theory used is the Theory of Customary Law, Theory and Theory Conflict Local Government. Methods This study is a qualitative research method, while engineering is a field study data collection (interviews), study the documentation and study of literature. While data analysis is done descriptively.This conflict resolution is still in the process of settlement, each party persisted with their respective opinions on the status of the disputed land, so that the two sides are still looking for a solution to get the best solution for both of them.Keywords: Resolution, Conflict, Communal Lan

    Partial duplication of the APBA2 gene in chromosome 15q13 corresponds to duplicon structures.

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    BackgroundChromosomal abnormalities affecting human chromosome 15q11-q13 underlie multiple genomic disorders caused by deletion, duplication and triplication of intervals in this region. These events are mediated by highly homologous segments of DNA, or duplicons, that facilitate mispairing and unequal cross-over in meiosis. The gene encoding an amyloid precursor protein-binding protein (APBA2) was previously mapped to the distal portion of the interval commonly deleted in Prader-Willi and Angelman syndromes and duplicated in cases of autism.ResultsWe show that this gene actually maps to a more telomeric location and is partially duplicated within the broader region. Two highly homologous copies of an interval containing a large 5' exon and downstream sequence are located approximately 5 Mb distal to the intact locus. The duplicated copies, containing the first coding exon of APBA2, can be distinguished by single nucleotide sequence differences and are transcriptionally inactive. Adjacent to APBA2 maps a gene termed KIAA0574. The protein encoded by this gene is weakly homologous to a protein termed X123 that in turn maps adjacent to APBA1 on 9q21.12; APBA1 is highly homologous to APBA2 in the C-terminal region and is distinguished from APBA2 by the N-terminal region encoded by this duplicated exon.ConclusionThe duplication of APBA2 sequences in this region adds to a complex picture of different low copy repeats present across this region and elsewhere on the chromosome
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