The relationship between the levels of salivary cortisol and the presence of xerostomia in menopausal women : a preliminary study

Xerostomia is a particularly frequent occurrence among menopausal women, and is often associated with depression. Objectives: To evaluate the relationship between unstimulated salivary flow rate and the presence of xerostomia, and to determine the levels of salivary cortisol and its relationship with xerostomia. Study design: Thirty women were selected from patients attending the Department of Medicine and Buccofacial surgery, and formed into two groups, study and control. Samples of unstimulated salivary flow were collected, and the amounts of salivary cortisol determined using the ELISA technique (enzyme-linked immunosorbent assay). Results: The mean unstimulated salivary flow rates for the control and study group were 0.37 ± 0.28 ml/min and 0.24 ± 0.18 ml/min, respectively. The concentration of salivary cortisol was 3.47 ± 1.64 ng/ml for the control group and 2.29 ± 2.60 ng/ml for the study group. The statistical tests applied showed no significant differences for either variable between the two groups in the study. Conclusions: The results of the present study indicate that there is no relationship between variations in the rates of unstimulated salivary flow and the corresponding concentration of cortisol

Non-face-to-face teaching of oral pathology through previous presentation of scientific articles in English

Elaboración de un dossier de artículos en Inglés en relación a cada unidad temática de la asignatura Patología Médica Bucal. Los artículos se presentarán al alumnado tras la clase magistral de cada área temática para fomentar la docencia “no presencial”.To prepare a file with articles in English about each of the subject areas of Oral Medical Pathology. The articles will be presented after the master class of each topic to encourage non-face-to-face teaching.Depto. de Especialidades Clínicas OdontológicasFac. de OdontologíaFALSEsubmitte

Xerostomia and Salivary Flow in Patients Taking Antihypertensive Drugs

The aims of this systematic review are (1) to compare the prevalence of xerostomia and hyposalivation between patients taking antihypertensive drugs with a control group (CG), (2) to compare salivary flow rate between patients treated with a CG, and (3) to identify which antihypertensives produce xerostomia. This systematic review was carried out according to the preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines. To evaluate methodological quality of the eligible studies Cochrane Collaboration tool for assessing the risk of bias for clinical trials and the modified Newcastle–Ottawa scale case-control studies were used. The databases were searched for studies up to November 19th 2019. The search strategy yielded 6201 results and 13 publications were finally included (five clinical trials and eight case-control studies). The results of the included studies did not provide evidence to state that patients taking antihypertensives suffer more xerostomia or hyposalivation than patients not taking them. With regard to salivary flow, only two clinical studies showed a significant decrease in salivary flow and even one showed a significant increase after treatment. The case–control studies showed great variability in salivary flow, but in this case most studies showed how salivary flow is lower in patients medicated with antihypertensive drugs. The great variability of antihypertensive drugs included, the types of studies and the outcomes collected made it impossible to study which antihypertensive drug produces more salivary alterations. The quality assessment showed how each of the studies was of low methodological quality. Therefore, future studies about this topic are necessary to confirm whether antihypertensive drugs produce salivary alterations

Development of a program of mixed radiolucent-radiopaque lesions imaging via radiographic cases for active learning in oral medicine

A través del presente proyecto se ha creado un fichero de imágenes radiográficas mixtas (radiopacas-radiolucidas) que serán utilizadas por los alumnos del tercer curso de Grado de la asignatura Medicina Bucal a fin de mejorar la enseñanza práctica del apartado lesiones radiográficas de los maxilares. Dichos ficheros se incorporarán al Campus Virtual para que el alumno pueda hacer uso de ellos. La elaboración de un fichero de estas características ha exigido en primer lugar la selección de las imágenes radiográficas mixtas de los maxilares más representativas. Se han seleccionado 43 imágenes radiográficas mixtas que se han clasificado en “Mixed Radiolucent-Radiopaque periapical lesions” (15 imágenes), “Mixed Radiolucent-Radiopaque pericoronal lesions” (8 imágenes) y “Mixed Radiolucent-Radiopaque lesions not necessarily contacting teeth“ ( 20 imágenes). Se han realizado 4 flowchart (el tercer grupo se subdividió en dos) para esquematizar las lesiones mixtas más frecuentes con sus características clínicas y radiográficas más habituales. Dichos flowchart ayudarán al alumno a poder llegar al diagnóstico de las lesiones de los casos clínicos seleccionados, cuya historia clínica también se ha reflejado. Todo el trabajo se ha realizado en dos idiomas inglés y español, que ayudará a los alumnos a aprender el vocabulario en inglés relacionado con el tema. Además, facilitará la comprensión de los alumnos de otras nacionalidades que pueden acudir a nuestra facultad y ayudará a los alumnos de la UCM que acuden a otras universidades Europeas o Americanas

Usefulness of implementing the OHIP-14 questionnaire to assess the impact of xerostomia and hyposalivation on qualityof life in patients with primary Sjögren's syndrome

Background: The aim of this study is to analyze if the results of the Oral Health Impact Profile-14 questionnaire (OHIP-14) in patients with primary Sjögren's syndrome (pSS) are correlated with salivary flow and level of xerostomia. Methods: This observational cross-sectional study was conducted in 61 patients (60 women, one man, mean age 57.64 [13.52]) diagnosed of pSS according to the American-European Criteria (2002). After recording demographic, medical and dental data (decayed-missing-filled teeth index [DMFT]), unstimulated (UWS) and stimulated (SWS) salivary flows were collected. Subsequently, UWS flow was categorized into two groups (0.7 ml/min). Patients also filled out a visual analog scale (VAS) for xerostomia and OHIP-14 for self-reported quality of life (QoL). Results: Data showed positive and significant correlation between OHIP-14 and xerostomia, based on VAS results (r = 0.52; p = 0.001). Furthermore, there was a negative correlation between UWS and OHIP-14 scores (r = -0.34; p = 0.006) and VAS for xerostomia (r = -0.22; p = 0.09). No significant correlation was found between SWS and OHIP-14 or VAS neither between DMFT and OHIP-14. When assessing the level of QoL by the UWS and SWS flow categories a significant association was found for UWS (p = 0.001) but not for SWS (p = 0.11). The OHIP-14 values were higher in the groups with lower salivary flow. The multiple linear regression to predict OHIP-14 only selected VAS for xerostomia as a statistically significant predictor. Conclusions: Increased level of xerostomia and reduced UWS flow decrease oral health-related QoL in patients with pSS

Salivary biomarkers in burning mouth syndrome: A systematic review and meta-analysis

The objective of this systematic review was to evaluate which salivary biomarkers are altered in patients with burning mouth syndrome (BMS) compared to a control group (CG). A comprehensive literature search was conducted in four databases. Case– control studies evaluating salivary biomarkers in BMS patients were included. Risk of bias was assessed using the Newcastle-Ottawa tool. RevMan was used for metaanalysis. Seventeen studies were selected. The included studies collected 54 different biomarkers. Of these biomarkers, only three (cortisol, α-amylase, and dehydroepiandrosterone) were analyzed in three or more studies. Dehydroepiandrosterone obtained contradictory results among the studies. However, cortisol and α-amylase levels were found to be higher in BMS patients. Cortisol was the only biomarker which could be included for meta-analysis. Cortisol levels were significantly higher in the BMS group compared to the CG (Mean Difference = 0.39; 95% CI [0.14–0.65]; p = 0.003). In conclusion, different studies investigated salivary biomarkers in patients with BMS compared to a CG, with controversial results. Meta-analysis, confirmed by trial-sequential analysis, showed how cortisol levels were significantly higher in BMS. Cortisol emerges as an interesting salivary biomarker in BMS, but future properly designed studies are needed to evaluate its role in diagnosis and/or response to treatment

Aprendizaje basado en juegos online para la mejora de la adquisición de competencias en Patología Médica Bucal

Estamos viviendo una situación complicada debido a la pandemia por el COVID-19. Durante el presente curso académico parte de nuestras asignaturas han pasado de una docencia presencial a una docencia online, esto ha sucedido en la asignatura Patología Médica Bucal del grado en Odontología. Este paso de la presencialidad a la docencia online requiere de nuevas medidas de motivación para aumentar la adquisición de conocimientos y mantener el aprendizaje activo. El objetivo de este proyecto ha sido aplicar diferentes juegos online para mejorar el aprendizaje en Patología Médica Bucal y la transferencia de conocimiento entre alumnos y profesores

PhDAY 2020 -FOO (Facultad de Óptica y Optometría)

Por cuarto año consecutivo los doctorandos de la Facultad de Óptica y Optometría de la Universidad Complutense de Madrid cuentan con un congreso propio organizado por y para ellos, el 4º PhDAY- FOO. Se trata de un congreso gratuito abierto en la que estos jóvenes científicos podrán presentar sus investigaciones al resto de sus compañeros predoctorales y a toda la comunidad universitaria que quiera disfrutar de este evento. Apunta en tu agenda: el 15 de octubre de 2020. En esta ocasión será un Congreso On-line para evitar que la incertidumbre asociada a la pandemia Covid-19 pudiera condicionar su celebración