Pinzas de escritura, integración visomotriz y coordinación motora en alumnado de segundo de primaria: Estudio descriptivo

Estudio descriptivo que permite valorar las pinzas de la escritura, la legibilidad, la integración visomotora y la coordinación motora en el alumnado de 2º de primaria en un colegio concertado de Zaragoza desde un enfoque de terapia ocupacional.<br /

Metabolic Syndrome in Rheumatoid Arthritis

Insulin resistance is an essential feature of the metabolic syndrome that has been linked to rheumatoid arthritis (RA). Understanding how inflammation arising in one tissue affects the physiology and pathology of other organs remains an unanswered question with therapeutic implications for chronic conditions including obesity, diabetes mellitus, atherosclerosis, and RA. Adipokines may play a role in the development of atherogenesis in patients with RA. Biologic therapies, such as TNF-α antagonists, that block proinflammatory cytokines have beneficial effects on the insulin resistance that is often observed in patients with RA

La documentación medieval del sur de Ávila y la variación interna del español : el corpus CODOMSA

El Corpus de Documentación Medieval del Sur de Ávila (CODOMSA), desarrollado por el Grupo de Estudios de Documentos Históricos y Textos Antiguos de la Universidad de Salamanca (GEDHYTAS), pretende servir de fuente de estudio para una de las zonas que marcan la transición entre el castellano septentrional y las variedades meridionales de la Península. Hasta el momento el corpus está integrado por más de 75 documentos anteriores a 1500 conservados en el Archivo Municipal de Mombeltrán (Ávila) y en el Archivo Histórico Municipal de Cuéllar (Segovia). Tras llevar a cabo una descripción del corpus, realizamos un análisis de algunos de los fenómenos lingüísticos más relevantes encontrados hasta la fecha, como la pérdida de /-s/ final, el ensordecimiento de las sibilantes, la neutralización de consonantes procedentes de grupos cultos latinos en posición implosiva o los desvíos en el sistema pronominal átono de 3.ª persona.The Corpus de Documentación Medieval del Sur de Ávila (CODOMSA), developed by the Group of Studies of Historical Documents and Old Texts of the University of Salamanca (GEDHYTAS), aims to serve as a study source for one of the areas that mark the transition between northern Castilian and the southern linguistic varieties of the Iberian Peninsula. Until now, CODOMSA is composed of more than 75 documents written before 1500 and preserved in the Municipal Archive of Mombeltrán (Ávila) and in the Historical Archive of Cuéllar (Segovia). After describing the corpus, we analyze some of the most relevant linguistic phenomena found to date, such as the loss of final /-s/, the desonorization of sibilants, the neutralization of consonants from Latin cult groups in implosive position or deviations in the unstressed pronominal system of 3rd person

A Straightforward Access to New Families of Lipophilic Polyphenols by Using Lipolytic Bacteria

The chemical synthesis of new lipophilic polyphenols with improved properties presents technical difficulties. Here we describe the selection, isolation and identification of lipolytic bacteria from food-processing industrial wastes, and their use for tailoring a new set of com- pounds with great interest in the food industry. These bacteria were employed to produce lipolytic supernatants, which were applied without further purification as biocatalysts in the chemoselective and regioselective synthesis of lipophilic partially acetylated phenolic com- pounds derived from olive polyphenols. The chemoselectivity of polyphenols acylation/dea- cylation was analyzed, revealing the preference of the lipases for phenolic hydroxyl groups and phenolic esters. In addition, the alcoholysis of peracetylated 3,4-dihydroxyphenylglycol resulted in a series of lipophilic 2-alkoxy-2-(3,4-dihydroxyphenyl)ethyl acetate through an unexpected lipase-mediated etherification at the benzylic position. These new compounds are more lipophilic and retained their antioxidant properties. This approach can provide access to unprecedented derivatives of 3,4-dihydroxyphenylglycol with improved propertiesJunta de Andalucía P08-NMR-3515, P11-CVI-7427 MO, FQM134 y BIO-213European Regional Development Fund (FEDER

Medieval documents from southern Avila and Spanish internal variation: corpus CODOMSA

El Corpus de Documentación Medieval del Sur de Ávila (CODOMSA), desarrollado por el Grupo de Estudios de Documentos Históricos y Textos Antiguos de la Universidad de Salamanca (GEDHYTAS), pretende servir de fuente de estudio para una de las zonas que marcan la transición entre el castellano septentrional y las variedades meridionales de la Península. Hasta el momento el corpus está integrado por más de 75 documentos anteriores a 1500 conservados en el Archivo Municipal de Mombeltrán (Ávila) y en el Archivo Histórico Municipal de Cuéllar (Segovia). Tras llevar a cabo una descripción del corpus, realizamos un análisis de algunos de los fenómenos lingüísticos más relevantes encontrados hasta la fecha, como la pérdida de /-s/ final, el ensordecimiento de las sibilantes, la neutralización de consonantes procedentes de grupos cultos latinos en posición implosiva o los desvíos en el sistema pronominal átono de 3.ª persona.El Corpus de Documentación Medieval del Sur de Ávila (CODOMSA), desarrollado por el Grupo de Estudios de Documentos Históricos y Textos Antiguos de la Universidad de Salamanca (GEDHYTAS), pretende servir de fuente de estudio para una de las zonas que marcan la transición entre el castellano septentrional y las variedades meridionales de la Península. Hasta el momento el corpus está integrado por más de 75 documentos anteriores a 1500 conservados en el Archivo Municipal de Mombeltrán (Ávila) y en el Archivo Histórico Municipal de Cuéllar (Segovia). Tras llevar a cabo una descripción del corpus, realizamos un análisis de algunos de los fenómenos lingüísticos más relevantes encontrados hasta la fecha, como la pérdida de /-s/ final, el ensordecimiento de las sibilantes, la neutralización de consonantes procedentes de grupos cultos latinos en posición implosiva o los desvíos en el sistema pronominal átono de 3.ª persona.El Corpus de Documentación Medieval del Sur de Ávila (CODOMSA), desarrollado por el Grupo de Estudios de Documentos Históricos y Textos Antiguos de la Universidad de Salamanca (GEDHYTAS), pretende servir de fuente de estudio para una de las zonas que marcan la transición entre el castellano septentrional y las variedades meridionales de la Península. Hasta el momento el corpus está integrado por más de 75 documentos anteriores a 1500 conservados en el Archivo Municipal de Mombeltrán (Ávila) y en el Archivo Histórico Municipal de Cuéllar (Segovia). Tras llevar a cabo una descripción del corpus, realizamos un análisis de algunos de los fenómenos lingüísticos más relevantes encontrados hasta la fecha, como la pérdida de /-s/ final, el ensordecimiento de las sibilantes, la neutralización de consonantes procedentes de grupos cultos latinos en posición implosiva o los desvíos en el sistema pronominal átono de 3.ª persona.The Corpus de Documentación Medieval del Sur de Ávila (CODOMSA), developed by the Group of Studies of Historical Documents and Old Texts of the University of Salamanca (GEDHYTAS), aims to serve as a study source for one of the areas that mark the transition between northern Castilian and the southern linguistic varieties of the Iberian Peninsula. Until now, CODOMSA is composed of more than 75 documents written before 1500 and preserved in the Municipal Archive of Mombeltrán (Ávila) and in the Historical Archive of Cuéllar (Segovia). After describing the corpus, we analyze some of the most relevant linguistic phenomena found to date, such as the loss of final /-s/, the desonorization of sibilants, the neutralization of consonants from Latin cult groups in implosive position or deviations in the unstressed pronominal system of 3rd person

Spontaneous Gelation of Adhesive Catechol Modified Hyaluronic Acid and Chitosan

Spontaneously formed hydrogels are attracting increasing interest as injectable or wound dressing materials because they do not require additional reactions or toxic crosslinking reagents. Highly valuable properties such as low viscosity before external application, adequate filmogenic capacity, rapid gelation and tissue adhesion are required in order to use them for those therapeutic applications. In addition, biocompatibility and biodegradability are also mandatory. Accordingly, biopolymers, such as hyaluronic acid (HA) and chitosan (CHI), that have shown great potential for wound healing applications are excellent candidates due to their unique physiochemical and biological properties, such as moisturizing and antimicrobial ability, respectively. In this study, both biopolymers were modified by covalent anchoring of catechol groups, and the obtained hydrogels were characterized by studying, in particular, their tissue adhesiveness and film forming capacity for potential skin wound healing applications. Tissue adhesiveness was related to o-quinone formation over time and monitored by visible spectroscopy. Consequently, an opposite effect was observed for both polysaccharides. As gelation advances for HA-CA, it becomes more adhesive, while competitive reactions of quinone in CHI-CA slow down tissue adhesiveness and induce a detriment of the filmogenic properties.This research was funding by Basque Government (ELKARTEK program, Department of Development and Infrastructures of the Basque Country, KK-2021-00040), University of the Basque Country UPV/EHU (GIU 207075), Ministry of Economy, Industry and Competitiveness (grant MAT2017-89553-P), CDTI of the Ministry of Science and Innovation (Spain) (GAMMAREGEN INNO-20182003) and i+Med S. Coop

5G spatial modeling of personal RF-EMF assessment within aircrafts cabin environments

Recently, new wireless communication systems within aircrafts cabins have drawn higher attention due to the growing demand of passenger services and applications and their corresponding requirements and constraints. In this regard, the fifth generation (5G) of wireless communication becomes an attractive and promising alternative to enable aircraft passengers' comfort and entertainment along the flight, considering its potential benefits in term of high data transfers and low latencies. Nevertheless, general population concern about radio frequency electromagnetic fields (RF-EMF) safety in general and, in particular to the environmental exposure at which we are all exposed in these flights, increases at the same time. Thus, in this work, we present an experimental campaign of measurements for current passengers' environmental exposure assessment, performed in different real generalizable type of flights and aircrafts' cabins, in order to provide current RF-EMF exposure insight within these complex heterogeneous environments. In addition, worst-case uplink 5G scenarios, where all 5G cellular handsets of the passengers operate at the same time, have been simulated by means of an in-house developed 3D Ray Launching (3D-RL) deterministic technique. Before takeoff and after landing, critical scenarios with the aircrafts' doors closed have been selected and assessed considering different types of modeled aircrafts full of passengers, considering 5G frequency range 2 (5G-FR2) operating links. The obtained results show that the operation frequency and the morphology and topology of the aircraft cabin have a great influence in the environmental RF-EMF passengers' spatial distribution and overall exposure, but not exceeding, even in worst case conditions, the international established regulatory limits. © 2022 IEEE.This work was supported by the Ministerio de Ciencia, Innovación y Universidades, Gobierno de España (MCIU/AEI/FEDER, UE) under Project RTI2018-095499-B-C31

Cepas bacterianas y sus usos en reacciones de acilación y/o desacilación

Cepas bacterianas y sus usos en reacciones de acilación y/o desacilación. La presente invención describe cepas microbianas con capacidad de llevar a cabo reacciones de alcoholisis y esterificación regioselectivas y el uso de las mismas en la producción de carbohidratos y polifenolas lipófilos de interés en la industria farmacéutica y alimentaria. Asimismo, la invención divulga el método de obtención de las cepas microbianas y el método de obtención de los carbohidratos y polifenoles lipofílicos.Españ

Towards environmental RF-EMF assessment of mmwave high-node density complex heterogeneous environments

The densification of multiple wireless communication systems that coexist nowadays, as well as the 5G new generation cellular systems advent towards the millimeter wave (mmWave) frequency range, give rise to complex context-aware scenarios with high-node density heterogeneous networks. In this work, a radiofrequency electromagnetic field (RF-EMF) exposure assessment from an empirical and modeling approach for a large, complex indoor setting with high node density and traffic is presented. For that purpose, an intensive and comprehensive in-depth RF-EMF E-field characterization study is provided in a public library study case, considering dense personal mobile communications (5G FR2 @28 GHz) and wireless 802.11ay (@60 GHz) data access services on the mmWave frequency range. By means of an enhanced in-house deterministic 3D ray launching (3D-RL) simulation tool for RF-EMF exposure assessment, different complex heterogenous scenarios of high complexity are assessed in realistic operation conditions, considering different user distributions and densities. The use of directive antennas and MIMO beamforming techniques, as well as all the corresponding features in terms of radio wave propagation, such as the body shielding effect, dispersive material properties of obstacles, the impact of the distribution of scatterers and the associated electromagnetic propagation phenomena, are considered for simulation. Discussion regarding the contribution and impact of the coexistence of multiple heterogeneous networks and services is presented, verifying compliance with the current established international regulation limits with exposure levels far below the aforementioned limits. Finally, the proposed simulation technique is validated with a complete empirical campaign of measurements, showing good agreement. In consequence, the obtained datasets and simulation estimations, along with the proposed RF-EMF simulation tool, could be a reference approach for the design, deployment and exposure assessment of the current and future wireless communication technologies on the mmWave spectrum, where massive high-node density heterogeneous networks are expected.Project RTI2018-095499-B-C31 was funded by the Ministerio de Ciencia, Innovación y Universidades, Gobierno de España (MCIU/AEI/FEDER, UE). This project received funding from Universidad Carlos III de Madrid and the European Union's Horizon 2020 research and innovation programme under Marie Sklodowska-Curie Grant 801538

Cepas bacterianas y sus usos en reacciones de acilación y/o desacilación

Cepas bacterianas y sus usos en reacciones de acilación y/o desacilación. La presente invención describe cepas microbianas con capacidad de llevar a cabo reacciones de alcoholisis y esterificación regioselectivas y el uso de las mismas en la producción de carbohidratos y polifenoles lipófilos de interés en la industria farmacéutica y alimentaria. Asimismo, la invención divulga el método de obtención de las cepas microbianas y el método de obtención de los carbohidratos y polifenoles lipofílicos.Españ