27 research outputs found

    Collective Intelligence: An Emerging World in Open Innovation

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    Responding to the lack of empirical research on the effect of collective intelligence on open innovation in the fourth industrial revolution, we examined the relationship between collective intelligence and open innovation. Collective intelligence or crowd innovation not only produces creative ideas or inventions, but also moderates any firm to innovate inside-out, outside-in, or in a coupled manner. We asked the following research questions: Does collective intelligence (or crowd innovation) motivate open innovation? Is there any difference in the effect of collective intelligence on open innovation by industry? These research questions led to the following three hypotheses: (1) Collective intelligence increases the performance of a firm, (2) collective intelligence will moderate the effect of open innovation, and (3) differences exist between the automotive industry and the pharmaceutical industry in these two effects. To empirically examine these three hypotheses, we analyzed the registered patents of these two industries from 2000 to 2014 over a 15-year period. These automotive and pharmaceutical patents were registered in the B60 category and the A61K category of the Korea Patent office, respectively. Collective intelligence was measured by co-invention. We found differences in the effects of collective intelligence on open innovation between the two industries. In the automotive industry, collective intelligence not only directly increased the performance, but also indirectly moderated the open innovation effect. However, this was not the case for the pharmaceutical industry. © 2019 by the authors.1

    Snake fang-inspired stamping patch for transdermal delivery of liquid formulations

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    A flexible microneedle patch that can transdermally deliver liquid-phase therapeutics would enable direct use of existing, approved drugs and vaccines, which are mostly in liquid form, without the need for additional drug solidification, efficacy verification, and subsequent approval. Specialized dissolving or coated microneedle patches that deliver reformulated, solidified therapeutics have made considerable advances; however, microneedles that can deliver liquid drugs and vaccines still remain elusive because of technical limitations. Here, we present a snake fang-inspired microneedle patch that can administer existing liquid formulations to patients in an ultrafast manner (< 15 s). Rear-fanged snakes have an intriguing molar with a groove on the surface, which enables rapid and efficient infusion of venom or saliva into prey. Liquid delivery is based on surface tension and capillary action. The microneedle patch uses multiple open groove architectures that emulate the grooved fangs of rear-fanged snakes: Similar to snake fangs, the microneedles can rapidly and efficiently deliver diverse liquid-phase drugs and vaccines in seconds under capillary action with only gentle thumb pressure, without requiring a complex pumping system. Hydrodynamic simulations show that the snake fang-inspired open groove architectures enable rapid capillary force-driven delivery of liquid formulations with varied surface tensions and viscosities. We demonstrate that administration of ovalbumin and influenza virus with the snake fang-inspired microneedle patch induces robust antibody production and protective immune response in guinea pigs and mice

    Quantitative gait analysis of idiopathic normal pressure hydrocephalus using deep learning algorithms on monocular videos

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    Abstract A vision-based gait analysis method using monocular videos was proposed to estimate temporo-spatial gait parameters by leveraging deep learning algorithms. This study aimed to validate vision-based gait analysis using GAITRite as the reference system and analyze relationships between Frontal Assessment Battery (FAB) scores and gait variability measured by vision-based gait analysis in idiopathic normal pressure hydrocephalus (INPH) patients. Gait data from 46 patients were simultaneously collected from the vision-based system utilizing deep learning algorithms and the GAITRite system. There was a strong correlation in 11 gait parameters between our vision-based gait analysis method and the GAITRite gait analysis system. Our results also demonstrated excellent agreement between the two measurement systems for all parameters except stride time variability after the cerebrospinal fluid tap test. Our data showed that stride time and stride length variability measured by the vision-based gait analysis system were correlated with FAB scores. Vision-based gait analysis utilizing deep learning algorithms can provide comparable data to GAITRite when assessing gait dysfunction in INPH. Frontal lobe functions may be associated with gait variability measurements using vision-based gait analysis for INPH patients

    Supplementary document for Enhancement of signal-to-noise ratio in fiber-optics based SERS detection by rough-cutting the end surface - 6327915.pdf

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    Enhancement of signal-to-noise ratio in fiber-optics based SERS detection by rough-cutting the end surfac

    The Effect of Open Innovation on Technology Value and Technology Transfer: A Comparative Analysis of the Automotive, Robotics, and Aviation Industries of Korea

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    With the advent of the Fourth Industrial Revolution, the Korean industrial environment has been rapidly changing. As a result, several industries are facing different innovation conditions, including: the automotive industry, which is a traditional manufacturing industry in Korea; the aerospace industry, which has been vertically integrated, and has been led by a single large company—Korea Aerospace Industries—since Korea went through an economic crisis in the 1990s; and the robotics industry, which is currently emerging. This study used parameters related to patents originating from the automobile, robotics, and aerospace fields. The patents subjected to analysis were those registered in Korea from 2001 to 2014, and included those that were applied for, jointly applied for, or registered by Korean companies. This study analyzed the differences caused by the effect of open innovation in the three industries. According to our results, first, the three industries experienced different effects of open innovation. Second, when large companies controlled a given industry, open innovation either worked a little or did not work at all. According to this research result, the Korean robotics industry, which has a weak dominance of large companies, experienced a strong effect of open innovation, in that joint patent applications led to economic gains from the patents and an increase in technology transfer and technology value. The aerospace industry of Korea, which has the highest dominance of large companies, experienced a slight effect of open innovation, as the effect of joint patent application only improved the technology value. Finally, the automotive industry of Korea had an intermediate level of open innovation, between the aerospace and robotics sectors

    The Signal of Post Catch-up in Open Innovation Dynamics

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    The digital transformation can serve as a window of opportunity for those late-comers who are equipped with the capability to create complementary assets for grabbing new opportunities of technological leapfrogging as a way of catch-up while penalising the forerunner. In this context, we want to answer the following research question. Is there any difference in open innovation effect on the firm according to the changing of belonging sectorial innovation system from catch-up to post-catch-up? We statistically analysed the moderating effects of open innovation between catching-up, and the performance with the patents which were registered in United States Patent and Trademark Office, which were applied from China in telecommunication, from South Korea in Semiconductors, and from Japan in biotechnology on 1995–1999, and 2005–2009. We found three results from this study: first, from this research, as the signal of post catching-up, open innovation effects on the performance of firm, and the moderating effects of open innovation between catching-up, and the performance of the firm were found; second, the appearance of new dominant design after post catching-up was explained through the powerful open innovation and third, open innovation could be a useful new strategy for firms in the post catching-up to use. © 2023 SAGE Publications.FALS

    Effects of Different Types of 3D Rest Frames on Reducing Cybersickness in a Virtual Environment

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    A virtual environment (VE) presents several kinds of sensory stimuli for creating a virtual reality. Some sensory stimuli presented in the VE have been reported to provoke cybersickness, which is caused by conflicts between sensory stimuli, especially conflicts between visual and vestibular sensations. Application of a rest frame has been known to be effective on reducing cybersickness by alleviating sensory conflict. The form and the way rest frames are presented in 3D VEs have different effects on reducing cybersickness. In this study, two different types of 3D rest frames were created. For verifying the rest frames' effects in reducing cybersickness, twenty subjects were exposed to two different rest frame conditions and a non-rest frame condition after an interval of three days in 3D VE. We observed the characteristic changes in the physiology of cybersickness in terms of autonomic regulation. Psychophysiological signals including EEG, EGG, and HRV were recorded and a simulator sickness questionnaire (SSQ) was used for measuring the intensity of the sickness before and after the exposure to the different conditions. In the results, the SSQ was reduced significantly in the rest frame conditions. Psychophysiological responses changed significantly in the rest frame conditions compared to the non-rest frame condition. The results suggest that the rest frame conditions have condition-specific effects on reducing cybersickness by differentially alleviating aspects of visual and vestibular sensory conflicts in 3D VE

    Reliability-Based Robust Design Optimization for Maximizing the Output Torque of Brushless Direct Current (BLDC) Motors Considering Manufacturing Uncertainty

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    In recent years, the deterministic design optimization method has been widely used to improve the output performance of brushless direct current (BLDC) motors. However, it does not contribute to reducing the failure rate and performance variation of products because it cannot determine the manufacturing uncertainty. In this study, we proposed reliability-based robust design optimization to improve the output torque of a BLDC motor while reducing the failure rate and performance variation. We calculated the output torque and vibration response of the BLDC motor using the electromagnetic–structural coupled analysis. We selected the tooth thickness, slot opening width, slot radius, slot depth, tooth width, magnet thickness, and magnet length as the design variables related to the shape of the stator and rotor that affect the output torque. We considered the distribution of design variables with manufacturing tolerances. We performed a reliability analysis of the BLDC motor considering the distribution of design variables with manufacturing tolerances. Using the reliability analysis results, we performed reliability-based robust design optimization (RBRDO) to maximize the output torque; consequently, the output torque increased by 8.8% compared to the initial BLDC motor, the standard deviation in output performance decreased by 46.9% with improved robustness, and the failure rate decreased by 99.2% with enhanced reliability. The proposed reliability-based robust design optimization is considered to be useful in the actual product design field because it can evaluate both the reliability and robustness of the product and improve its performance in the design stage
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