Near-field antenna testing using the Hewlett Packard 8510 automated network analyzer

Near-field antenna measurements were made using a Hewlett-Packard 8510 automated network analyzer. This system features measurement sensitivity better than -90 dBm, at measurement speeds of one data point per millisecond in the fast data acquisition mode. The system was configured using external, even harmonic mixers and a fiber optic distributed local oscillator signal. Additionally, the time domain capability of the HP8510, made it possible to generate far-field diagnostic results immediately after data acquisition without the use of an external computer

Optically interconnected phased arrays

Phased-array antennas are required for many future NASA missions. They will provide agile electronic beam forming for communications and tracking in the range of 1 to 100 GHz. Such phased arrays are expected to use several hundred GaAs monolithic integrated circuits (MMICs) as transmitting and receiving elements. However, the interconnections of these elements by conventional coaxial cables and waveguides add weight, reduce flexibility, and increase electrical interference. Alternative interconnections based on optical fibers, optical processing, and holography are under evaluation as possible solutions. In this paper, the current status of these techniques is described. Since high-frequency optical components such as photodetectors, lasers, and modulators are key elements in these interconnections, their performance and limitations are discussed

Optically controlled phased-array antenna technology for space communication systems

Using MMICs in phased-array applications above 20 GHz requires complex RF and control signal distribution systems. Conventional waveguide, coaxial cable, and microstrip methods are undesirable due to their high weight, high loss, limited mechanical flexibility and large volume. An attractive alternative to these transmission media, for RF and control signal distribution in MMIC phased-array antennas, is optical fiber. Presented are potential system architectures and their associated characteristics. The status of high frequency opto-electronic components needed to realize the potential system architectures is also discussed. It is concluded that an optical fiber network will reduce weight and complexity, and increase reliability and performance, but may require higher power

Using a modified Hewlett Packard 8410 network analyzer as an automated farfield antenna range receiver

A Hewlett Packard 8410 Network Analyzer was modified to be used as an automated far-field antenna range receiver. By using external mixers, analog to digital signal conversion, and an external computer/controller, the HP8410 is capable of measuring signals as low as -110 dBm. The modified receiver is an integral part of an automated far-field range which features computer controlled test antenna positioning, system measurement parameters, and data acquisition, as well as customized measurement file management. The system described was assembled and made operational, taking advantage of off-the-shelf hardware available at minimal cost

Design of an optically controlled Ka-band GaAs MMIC phased-array antenna

Phased array antennas long were investigated to support the agile, multibeam radiating apertures with rapid reconfigurability needs of radar and communications. With the development of the Monolithic Microwave Integrated Circuit (MMIC), phased array antennas having the stated characteristics are becoming realizable. However, at K-band frequencies (20 to 40 GHz) and higher, the problem of controlling the MMICs using conventional techniques either severely limits the array size or becomes insurmountable due to the close spacing of the radiating elements necessary to achieve the desired antenna performance. Investigations were made that indicate using fiber optics as a transmission line for control information for the MMICs provides a potential solution. By adding an optical interface circuit to pre-existing MMIC designs, it is possible to take advantage of the small size, lightweight, mechanical flexibility and RFI/EMI resistant characteristics of fiber optics to distribute MMIC control signals. The architecture, circuit development, testing and integration of optically controlled K-band MMIC phased array antennas are described

Optical RF distribution links for MMIC phased array antennas

Conventional methods to distribute RF signals to GaAs Monolithic Microwave Integrated Circuits Phased Array Antennas are inadequate for arrays having large numbers of elements. Optical RF distribution links have been proposed as a lightweight, mechanically flexible, and low volume solution. Three candidate techniques for providing optical RF distribution are discussed along with the electro-optic devices required to configure them. A discussion of the present status of applicable electro-optics devices is also included

Direct Data Distribution From Low-Earth Orbit

NASA Lewis Research Center (LeRC) is developing the space and ground segment technologies necessary to demonstrate a direct data distribution (1)3) system for use in space-to-ground communication links from spacecraft in low-Earth orbit (LEO) to strategically located tracking ground terminals. The key space segment technologies include a K-band (19 GHz) MMIC-based transmit phased array antenna, and a multichannel bandwidth- and power-efficient digital encoder/modulate with an aggregate data rate of 622 Mb/s. Along with small (1.8 meter), low-cost tracking terminals on the ground, the D3 system enables affordable distribution of data to the end user or archive facility through interoperability with commercial terrestrial telecommunications networks. The D3 system is applicable to both government and commercial science and communications spacecraft in LEO. The features and benefits of the D3 system concept are described. Starting with typical orbital characteristics, a set of baseline requirements for representative applications is developed, including requirements for onboard storage and tracking terminals, and sample link budgets are presented. Characteristics of the transmit array antenna and digital encoder/modulator are described. The architecture and components of the tracking terminal are described, including technologies for the next generation terminal. Candidate flights of opportunity for risk mitigation and space demonstration of the D3 features are identified

Transcriptome Analysis of Mouse Stem Cells and Early Embryos

Understanding and harnessing cellular potency are fundamental in biology and are also critical to the future therapeutic use of stem cells. Transcriptome analysis of these pluripotent cells is a first step towards such goals. Starting with sources that include oocytes, blastocysts, and embryonic and adult stem cells, we obtained 249,200 high-quality EST sequences and clustered them with public sequences to produce an index of approximately 30,000 total mouse genes that includes 977 previously unidentified genes. Analysis of gene expression levels by EST frequency identifies genes that characterize preimplantation embryos, embryonic stem cells, and adult stem cells, thus providing potential markers as well as clues to the functional features of these cells. Principal component analysis identified a set of 88 genes whose average expression levels decrease from oocytes to blastocysts, stem cells, postimplantation embryos, and finally to newborn tissues. This can be a first step towards a possible definition of a molecular scale of cellular potency. The sequences and cDNA clones recovered in this work provide a comprehensive resource for genes functioning in early mouse embryos and stem cells. The nonrestricted community access to the resource can accelerate a wide range of research, particularly in reproductive and regenerative medicine

Trophoblast organoids as a model for maternal-fetal interactions during human placentation.

The placenta is the extraembryonic organ that supports the fetus during intrauterine life. Although placental dysfunction results in major disorders of pregnancy with immediate and lifelong consequences for the mother and child, our knowledge of the human placenta is limited owing to a lack of functional experimental models1. After implantation, the trophectoderm of the blastocyst rapidly proliferates and generates the trophoblast, the unique cell type of the placenta. In vivo, proliferative villous cytotrophoblast cells differentiate into two main sub-populations: syncytiotrophoblast, the multinucleated epithelium of the villi responsible for nutrient exchange and hormone production, and extravillous trophoblast cells, which anchor the placenta to the maternal decidua and transform the maternal spiral arteries2. Here we describe the generation of long-term, genetically stable organoid cultures of trophoblast that can differentiate into both syncytiotrophoblast and extravillous trophoblast. We used human leukocyte antigen (HLA) typing to confirm that the organoids were derived from the fetus, and verified their identities against four trophoblast-specific criteria3. The cultures organize into villous-like structures, and we detected the secretion of placental-specific peptides and hormones, including human chorionic gonadotropin (hCG), growth differentiation factor 15 (GDF15) and pregnancy-specific glycoprotein (PSG) by mass spectrometry. The organoids also differentiate into HLA-G+ extravillous trophoblast cells, which vigorously invade in three-dimensional cultures. Analysis of the methylome reveals that the organoids closely resemble normal first trimester placentas. This organoid model will be transformative for studying human placental development and for investigating trophoblast interactions with the local and systemic maternal environment.Centre for Trophoblast Reearch Royal Society Dorothy Hodgkin Fellowship Marie Curie Intra-European Fellowshi

Seabed seismographs reveal duration and structure of longest runout sediment flows on Earth

Turbidity currents carve the deepest canyons on Earth, deposit its largest sediment accumulations, and break seabed telecommunication cables. Powerful canyon-flushing turbidity currents break sensors placed in their path, making them notoriously challenging to measure, and thus poorly understood. This study provides the first remote measurements of canyon-flushing flows, using ocean-bottom seismographs located outside the flow's destructive path, revolutionizing flow monitoring. We recorded the internal dynamics of the longest sediment flows yet monitored on Earth, which traveled >1,000 km down the Congo Canyon-Channel at 3.7–7.6 m s−1 and lasted >3 weeks. These observations allow us to test fundamental models for turbidity current behavior and reveal that flows contain dense and fast frontal-zones up to ∼400 km in length. These frontal-zones developed near-uniform durations and speeds for hundreds of kilometres despite substantial seabed erosion, enabling flows to rapidly transport prodigious volumes of organic carbon, sediment, and warm water to the deep-sea