Polish Delegations in Kazakhstan During the Second World War: Alma-Аtа and Semipalatinsk

Introduction. The article investigates the versatile activities of Polish diplomats on the example of the representative offices of the embassy of Poland (delegations) in Alma-Ata (Almaty) and Semipalatinsk (Semey). Documents in the Kazakhstani archives indicate the presence of nine delegations created during the war in Kazakhstan to facilitate the formation of the Polish army (Anders Army). Polish “delegates” – diplomats, military, civilian employees – helped to rescue the Poles from places of detention and settlements, to draw up their documents for further sending to the army. Materials. Documents of the “especially valuable” fund of the Semipalatinsk Archive (currently the Documentation Center of Modern History of the East Kazakhstan Region, Semey), which are put into scientific circulation for the first time, testify to the versatile activities of Polish delegations in a large space in the east of the country. Analysis and Results. Polish delegates organized not only military-political and consular issues, but also economic, social, humanitarian activities. Polish employees worked in contact with Soviet institutions. They provided social support to both the military and displaced, evacuated, orphans, and disabled people. The organization of orphanages and shelters for Polish children was carried out, including by the efforts of Polish diplomats. The Poles who returned after the war to their homeland organized societies of the so-called “sybyraki”. Today they act as a kind of bridge in relations between Kazakhstan and Poland

Characteristics of cholera strains isolated in Kazakhstan

In the Republic of Kazakhstan there are three types of areas with different cholera infection risk levels for people. Within cholera epidemiological surveillance the cholera strains are annually isolated from people and the environment. In this research, we studied the cholera strains isolated in Kazakhstan for 2013-2015 and they were selected for this study. All cholera strains were locally isolatedfrom people and the environment except one toxigenic imported strain of V. cholerae 01 lnaba which had genes of ctxAB, tcpA. The study showed that there were V cholerae strains which were atypical by their agglutination abilities and sensitivity to cholera phages. It can complicate the cholera laboratory diagnostics especially the diagnostics of V. cholerae О1 and for timely recognition of cholera it is necessary to carry out the diagnostics combined with molecular and genetic methods. For the study of antibiotic sensitivity or resistance we use eight antibacterial preparations. Cholera strains isolated in Kazakhstan did not have antibiotic resistance to the studied preparations. But the cholera strain brought from Pakistan was resistant to ciprofloxacin. The lack of strong resistance of local strains to the antibacterial drugs studied is encouraging in terms of conducting aetiotropic therapy. However, the possibility of entering of antibiotic-resistant strains into Kazakhstan obliges regularly to monitor strains for their sensitivity to antibacterial drugs

Spermidine as a promising anticancer agent: Recent advances and newer insights on its molecular mechanisms

Spermidine is a naturally occurring polyamine compound found in semen. It is also found in several plant sources and boasts a remarkable biological profile, particularly with regards to its anticancer properties. Spermidine specifically interferes with the tumour cell cycle, resulting in the inhibition of tumor cell proliferation and suppression of tumor growth. Moreover, it also triggers autophagy by regulating key oncologic pathways. The increased intake of polyamines, such as spermidine, can suppress oncogenesis and slow the growth of tumors due to its role in anticancer immunosurveillance and regulation of polyamine metabolism. Spermidine/spermine N-1-acetyltransferase (SSAT) plays a critical role in polyamine homeostasis and serves as a diagnostic marker in human cancers. Chemically modified derivatives of spermidine hold great potential for prognostic, diagnostic, and therapeutic applications against various malignancies. This review discusses in detail the recent findings that support the anticancer mechanisms of spermidine and its molecular physiology

Catalogs of ground motion parameters for earthquake-prone regions in Kazakhstan

The catalogs of ground motion parameters for earthquake-prone regions of Kazakhstan used for modeling seismic effects in seismic hazard assessment and microzonation are presented

Probabilistic seismic hazard assessment of Kazakhstan and Almaty city in peak ground accelerations

As for many post-soviet countries, Kazakhstan's building code for seismic design was based on a deterministic approach. Recently, Kazakhstan seismologists are engaged to adapt the PSHA (probabilistic hazard assessment) procedure to the large amount of available geological, geophysical and tectonic Kazakh data and to meet standard requirements for the Eurocode 8. The new procedure has been used within National projects to develop the Probabilistic GSZ (General Seismic Zoning) maps of the Kazakhstan territory and the SMZ (Probabilistic Seismic Microzoning) maps of Almaty city. They agree with the seismic design principles of Eurocode 8 and are expressed in terms of not only seismic intensity, but also engineering parameters (peak ground acceleration PGA). The whole packet of maps has been developed by the Institute of Seismology, together with other Kazakhstan Institutions. Our group was responsible for making analysis in PGA. The GSZ maps and hazard assessment maps for SMZ in terms of PGA for return periods 475 and 2475 years are considered in the article. Keywords: Probabilistic seismic hazard assessment, Seismic zoning map, Peak ground acceleration, Seismic sources, Seismotectonic setting, Seismic regime, Ground motion prediction equation

Seismic ground motion variations resulting from site conditions

Amplification of seismic ground motions in the territory of Almaty city is evaluated by using different methods. The pattern and probable causes of ground motion variations in different engineering-geological conditions are characterized. An expeditious application of these techniques within a complex methodical approach for Almaty city microzonation is considered

The level of the general reactivity of erythrocytes membranes in rats with combined action of infrasound

This study focuses on the level of the general reactivity of erythrocytes membranes in rats with combined action of infrasound. The effect on biological features was investigated through the experiments on the rats. Comparative analysis of immunological parameters, the permeability of erythrocyte membranes and the electrical conductivity of blood in rats under the effects of infrasound at a frequency of 15 Hz and intensity 11 dB through exposure time of 3-3600 seconds allowed proving that infrasound causes nonspecific changes at the cellular and subcellular levels of the organism. There was used many different technologies and methods. Based on the obtained results, direct indirect and combined effect of infrasound immunological parameters had clearly increased the total count of leukocyte index and all parameters of differential count of leukocytes as well as appearance immature products in the peripheral blood

The Contribution of Migration to Sustainable Development: Western Vector of Migration from Central Asia (the US Case)

The 2030 Agenda for Sustainable Development recognizes for the first time the favorable contribution of migration to sustainable development. This document is called the “declaration of interdependence”, which is especially true for migration, which connects countries of origin and destination countries and has a huge impact on the lives of millions of migrants and their families. In the context of globalization, international migration has become a key challenge for both global development as well as for some state actors. At the present time there are several attractive centers on the planet for migration, which include highly advanced European Union countries, the United States, Canada and others. Although a number of issues of the migration process from the Central Asian republics to the United States are considered to be typical for any nation in the context of globalization, there are some regional peculiarities. The issue of immigration of the Central Asians to the United States is undoubtedly relatively a new and less studied phenomenon. The article provides a comparative analysis of the causes and consequences of the migration movement “overseas” in a country context, and its impact on diaspora relations. The goal of the article is to analyze of the migration process from the Central Asian republics to the United States in connection with international migration trends in the context of the Sustainable Development Goals (SDGs), and the Global Compact for Safe, Orderly and Regular Migration (GCM)

Environmental migration through the prism of United Nations sustainable development goals

The article is devoted to the problems of environmental migration in the context of the Sustainable Development Goals proclaimed by the United Nations at the General Assembly session in 2015. Environmental migration has long been the subject of study by various scientists, where in the need for an integrated attitude to the study of this phenomenon is noted. However, to date, there is no systematic approach to studying the problem of environmental migration: scientists consider this process from the point of view of a specific area of their scientific interests. Most often, the points of view of representatives of natural and social sciences are paradigmatically indicated, sometimes they are opposite in their content. The study of environmental migration through the prism of Sustainable Development Goals provides, in our opinion, a comprehensive, interdisciplinary approach. The article attempts to systematically investigate the phenomenon of environmental migration using the consequences of the ecological crisis in the Aral Sea region as an example

Features of the Transition From the Traditional to the Criterial Assessment in Schools of Kazakhstan

This study discusses the features of the transition from the traditional assessment system to the criteria-based assessment in schools of Kazakhstan. The use of criterion assessment in schools in Kazakhstan contributes to the crowding out of traditional methods of assessment and leads to a new vision of the methods and technologies of the system for evaluating educational achievements. In connection with the modernization of Kazakhstan’s education, significant changes are occurring in the control and assessment activities of Kazakhstan schools, its goals, content, and technologies are changing. The problem of assessment activity is one of the most urgent problems both in pedagogical theory and in pedagogical practice. This study presents the results of empirical studies and the features of the transition to a new criteria-based assessment system for Kazakhstan. According to the results of the study, the problem of the need for professional training of future primary school teachers for the criteria-based assessment system was revealed. Results also showed that there are difficulties of applying criteria-based assessment in the practice of primary school teachers. The question of what professional knowledge, skills, and abilities an elementary school teacher must possess to successfully perform the monitoring and evaluation function was investigated. Particular attention is paid to the study of the influence of criteria-based assessment on learning motivation in primary school