Assessment of forest roads and firebreaks in Turkey

No Abstrac

Recursive Partitioning Analysis of Mediastinal N2 Lymph Node Involvement with Selected Biological Markers in Operable Non-small Cell Lung Cancer: A Correlative Study

Background: Expressions of various biomarkers in non-small cell lung cancer (NSCLC) have been linked with the prognosis and involvement of mediastinal lymph nodes.Methods: In this study, we utilized recursive partitioning analysis (RPA) by using P53, c-erb-B2, and P-glycoprotein (PGP) expressions evaluated by immunohistochemistry to estimate retrospectively the likelihood of the occult N2 mediastinal lymph node involvement in patients with operable NSCLC.Results: In univariate tests, immunohistochemical staining of the primary tumor for these 3 markers in 61 patients undergoing surgery revealed no direct relationship with the N2 involvement. However, RPA demonstrated in patients aged 75 and with 4 mediastinal lymph nodes removed that, high PGP expression frequency (20%) predicted an increased likelihood of the N2 involvement (46.7%, R2 = 0.25). Univariate nominal logistic regression analysis revealed that RPA group affiliation, and the number of mediastinal lymph nodes resected (logarithmic transformation) were associated with the metastasis to N2 lymph nodes (χ2 = 17.59, p = 0.0005, and χ2 = 2.40, p = 0.0654, respectively). Multivariate analysis confirmed that only RPA group affiliation predicted the N2 involvement (χ2 = 14.63, p = 0.0022).Conclusion: This study shows for the first time that PGP expression of the primary tumor may help to predict the occult N2 mediastinal lymph node involvement in NSCLC. Thus, further research is required to understand whether PGP expression may aid in the decision process for preoperative mediastinoscopy

Assessment of the impact of isolated coronary artery ectasia on left ventricular functions with 3D speckle-tracking echocardiography

PubMed ID: 31742786Background: Coronary artery ectasia (CAE) is an angiographic definition of coronary artery pathology in which the diameter of the ectatic segment measures more than 1.5 times the diameter of an adjacent healthy reference segment. No previous study has reported on the use of 3D-STE for assessing the left ventricular (LV) functions in patients with isolated CAE. As a result of this, we aimed to evaluate the effects of isolated CAE on LV functions using 3D-STE in the present study. Methods: Ninety-one patients with isolated CAE and 90 controls who proved to have normal coronary angiograms were enrolled to the study. 3D-STE was performed and GLS, GCS, GAS, and GRS were obtained for every subject after coronary angiography. Results: The mean age of the patients was 61.75 ± 10.02 years, and 71.8% were male. GLS, GCS, GAS, and GRS were significantly depressed in the isolated CAE group than in the control group (P -16 has 92.1 % sensitivity, 88.5 % specificity; and a GCS value of >-20 has 86.7 % sensitivity, 89.2 % specificity to detect the presence of isolated CAE. Conclusion: Isolated CAE has a considerable negative effect on LV functions as evaluated by 3D-strain parameters, and 3D-STE could be an effective method to detect early stage myocardial impairment in patients with isolated CAE. © 2019 Wiley Periodicals, Inc

Effect of inter- and intra-annual thermohaline variability on acoustic propagation

This paper is to answer the question “How can inter- and intra-annual variability in the ocean be leveraged by the submarine Force?” through quantifying inter- and intra-annual variability in (T, S) fields and in turn underwater acoustic characteristics such as transmission loss, signal excess, and range of detection. The Navy’s Generalized Digital Environmental Model (GDEM) is the climatological monthly mean data and represents mean annual variability. An optimal spectral decomposition method is used to produce a synoptic monthly gridded (SMG) (T, S) dataset for the world oceans with 1o×1o horizontal resolution, 28 vertical levels (surface to 3,000 m depth), monthly time increment from January 1945 to December 2014 now available at the NOAA/NCEI website: http://data.nodc.noaa.gov/cgi- bin/iso?id=gov.noaa.nodc:0140938. The sound velocity decreases from 1945 to 1975 and increases afterwards due to global climate change. Effect of the inter- and intra-annual (T, S) variability on acoustic propagation in the Yellow Sea is investigated using a well-developed acoustic model (Bellhop) in frequencies from 3.5 kHz to 5 kHz with sound velocity profile (SVP) calculated from GDEM and SMG datasets, various bottom types (silty clay, fine sand, gravelly mud, sandy mud, and cobble or gravel) from the NAVOCEANO‘s High Frequency Environmental Algorithms (HFEVA), source and receiver depths. Acoustic propagation ranges are extended drastically due to the inter-annual variability in comparison with the climatological SVP (from GDEM). Submarines’ vulnerability of detection as its depth varies and avoidance of short acoustic range due to inter-annual variability are also discussed

Evaluation of newborn patients with patent ductus arteriosus and indomethacin treatment [Yenidogan bebeklerde patent duktus arteriozus ve indometazin tedavisinin degerlendirilmesi]

In this study, 34 babies with symptomatic patent ductus arteriosus (PDA) were evaluated and followed up in the neonatal intensive care unit between 1994-1996. The association of other cardiac defects with PDA was seen in eight (23.5%) cases. PDA was diagnosed postnatally between the 2nd and 36th days (mean 9.0±6.7). Indomethacin treatment was given (1-12 doses, mean 3.4±1.9) to 26 babies (76.5%) between the 3rd and 15th days (mean 7.8±3.6). Ductus arteriosus closed in 21 cases (80.8%) after indomethacin treatment. Adverse effects were not seen in any cases. We conclude that of indomethacin therapy is important for treatment of patients with PDA

Food allergy profile in tertiary clinics in southeast part of Turkey: 'a multi center study'

31st Congress of the European-Academy-of-Allergy-and-Clinical-Immunology (EAACI) -- JUN 16-20, 2012 -- Geneva, SWITZERLANDWOS: 000310247703139…European Acad Allergy & Clin Immunol (EAACI