162 research outputs found

    Secondary or Transient Pseudohypoaldosteronism Associated With Urinary Tract Anomaly and Urinary Infection: A Case Report

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    AbstractHyponatremia with hyperkalemia in infancy is a rare presentation, but may be due to aldosterone deficiency or end organ resistance to its action. There are few cases associating this condition with urinary tract infections or anatomic abnormalities that predispose to infection. Clinicians should have a high index of suspicion in diagnosing secondary pseudohypoaldosteronism (PHA) due to its often atypical presentation. We describe ten month-old infant who presented with this condition and was found to have urinary tract infection complicating unilateral urinary tract anomaly, which may have strong association with renal tubular resistance to aldosterone

    ALGORITHMS FOR CONSTRUCTING EDGE MAGIC TOTAL LABELING OF COMPLETE BIPARTITE GRAPHS

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    The study of graph labeling has focused on finding classes of graphs which admits a particular type of labeling. In this paper we consider a particular class of graphs which demonstrates Edge Magic Total Labeling. The class we considered here is a complete bipartite graph Km,n. There are various graph labeling techniques that generalize the idea of a magic square has been proposed earlier. The definition of a magic labeling on a graph with v vertices and e edges is a one to one map taking the vertices and edges onto the integers 1,2,3,………, v+e with the property that the sum of the label on an edge and the labels of its endpoints is constant independent of the choice of edge. We use m x n matrix to construct edge magic total labeling of Km,n

    MFC-09-1: A New Forage Cowpea (\u3cem\u3eVigna unguiculata\u3c/em\u3e (L.) Walp) Variety for South Zone of India

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    Cowpea (Vigna unguiculata (L.) Walp) is a leguminous crop grown throughout West Africa, often in association with pearl millet and sorghum. Cowpea is well adapted to the harsh growing conditions, including low soil fertility, high temperatures, and drought. Cowpea can fix atmospheric nitrogen to improve soil fertility and cropping system productivity. Additionally, farmers feed cowpea fodder to livestock to increase income, and collect the manure produced for use in their fields thereby reduces farmers’ reliance on commercial fertilizers and sustains soil fertility. Previous studies with cowpea indicated that this legume improves soil fertility and enhances the intake and utilization of poor quality roughage consequently improving livestock production and productivity

    Performance of Dual Purpose Pearl Millet Genotypes as Influenced by Cutting Management and Nitrogen Levels

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    Pearl millet (Pennisetum glaucum L.) is important minor millets cultivated both for food and fodder. The dual purpose nature of pearl millet has recently identified due to its profused tillering, repeated harvesting and absence of anti nutritional factor. In fodder crops, the production potential can be manipulated by fertilizer management and time of harvest. In this regard, peal millet no exception, scientific study on cutting and nitrogen management on green fodder yield, quality and grain yield is meagre. Therefore, the present investigation was under taken to study the influence of cutting management and nitrogen levels on green forage and grain yield of dual purpose pearl millet

    Enhancing Productivity of Guinea Grass Variety JHGG-08-1 through Agro-Techniques in Southern Dry Zone of Karnataka

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    Guinea grass (Panicum maximum) is a major pan tropical grass used throughout the tropics for pasture, cut-and-carry, silage and hay. It is a fast growing and leafy grass, which is palatable to livestock with a good nutritional value. However, it is generally recommended to supplement it with sources of protein in order to meet nutritional requirements or improve animal performance. It grows well on a wide variety of well drained soils of good fertility and it is a good vegetative barrier. It can survive quick moving fires which does not harm the underground roots and drought because of the deep, dense and fibrous root system. The potentiality of the varieties varies with agro climatic situation and soil type, keeping these things in view, the present investigation was undertaken to identify the optimum plant population and nutrient levels for enhancing the productivity and quality of guinea grass variety JHGG-08- in southern Zone of Karnataka

    Performance of Guinea Grass Variety JHGG-08-1 in Southern Region of Karnataka

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    Guinea grass (Panicum maximum) is native to Africa but this grass was introduced to almost all tropical countries as a source of animal forage. It grows well on a wide variety of well drained soils of good fertility and it is suitable for vegetative barrier and conservation of soil. It can survive quick moving fires which does not harm the underground roots and drought because of the deep, dense and fibrous root system. The Potentiality of the varieties varies with agro climatic situation and soil type. Keeping these things in view, the present investigation was taken up to study the performance of Guinea grass varieties in southern dry zone of Karnataka under protective irrigation

    The V Advancement Flap Sans Y Closure in Treatment of Volar Foot Ulcers

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    Background: Management of foot ulcer is challenging for plastic surgeons owing to inherent sturdiness of the volar skin and also the necessity to give a robust cover to ensure functionality including weight bearing. This study was conducted to examine the results of our technique of single or double ‘V’ advancement flap sans the ‘Y’ closure of the classical ‘VY’ flap, which was found to be technically simple for the management of plantar ulcers in our foot ulcer patients. Methods and Material: 37 patients hospitalized for the management of foot plantar ulcer, who underwent repair with our modified ‘V’ flap advancement without ‘Y’ closure technique, at our institution were included in the study. Demographic data, disease-related parameters, technique related complications data were recorded and analysed. Technique complications or sequelae, if any, were accounted. Descriptive statistics was used to summarize the findings. Results: In our study, 23 men and 14 women were there with their ages ranging from 15 to 87 years (mean = 54.1 years). The diameter of the ulcers ranged from 14 to 26 mm with mean of 19.3 mm. Unilateral V (-Y) advancement flap was used in 26 cases and in 11 cases bilateral V (-Y) advancement flap was used. Complications included wound dehiscence (3) and partial flap loss (1) of which 3 required redo surgeries while one healed with secondary intention. Conclusions: Though a relatively small study group our technique well suited the needs for plantar ulcer wound closure with acceptable complication rate. Key Messages: Foot ulcer management is a therapeutic challenge which, if managed efficiently reduces encumbrance. Our technique represents a useful and reliable technique with advantages of excellent colour and texture matching and primary donor site closure. Keywords: VY advancement flap, Plantar foot ulcer, Diabetic ulcer, Malignant foot ulcer, Trophic ulcer, Traumatic ulce

    Primary Carcinoma of the Fallopian Tube: A Review of a Single Institution Experience of 8 Cases

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    Aims and Objectives. To evaluate the clinicopathologic features, response to cytoreductive surgery and adjuvant platinum-based chemotherapy with or without paclitaxel. Materials and Methods. A retrospective observational study of 8 women with a histopathologic diagnosis of primary fallopian tube carcinoma (PFTC) from January 2000 to February 2013. Results. 4/8 (50%) of the women were in the early stage and an intraoperative frozen section was 100% effective in identifying fallopian tube carcinoma and then a staging laparotomy was performed. All 4/8 cases in the early stage had received and responded to single agent carboplatin and all are alive without clinical, radiological, or biochemical evidence of recurrence at the end of 2 years and the longest survivor has completed 13 years. Primary optimal cytoreductive surgery was achievable in 3/4 (75%) in advanced disease. All showed response to adjuvant paclitaxel and carboplatin (T+C), but all had succumbed to the disease following recurrence with mean progression-free survival of 19 months (range 15–21 months) and mean overall survival of 27 months (range 22–36 months). Conclusion. The pivotal role played by a frozen section in diagnosing PFTC which is rare needs to be reemphasized, therefore justifying a primary staging laparotomy in an early stage. Prolonged survival observed in this group following an optimum tailored adjuvant single agent carboplatin is worth noting

    Biosynthesized ZnO-NPs from Morus indica attenuates methylglyoxal-induced protein glycation and RBC damage: In-vitro, in-vivo and molecular docking study

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    The development of advanced glycation end-products (AGEs) inhibitors is considered to have therapeutic potential in diabetic complications inhibiting the loss of the biomolecular function. In the present study, zinc oxide nanoparticles (ZnO-NPs) were synthesized from aqueous leaf extract of Morus indica and were characterized by various techniques such as ultraviolet (UV)-Vis spectroscopy, Powder X-Ray Diffraction (PXRD), Fourier Transform Infrared Spectroscopy (FT-IR), Scanning electron microscopy (SEM), and energy dispersive spectroscopy (EDS). Further, the inhibition of AGEs formation after exposure to ZnO-NPs was investigated by in-vitro, in-vivo, and molecular docking studies. Biochemical and histopathological changes after exposure to ZnO-NPs were also studied in streptozotocin-induced diabetic rats. ZnO-NPs showed an absorption peak at 359 nm with a purity of 92.62% and ~6–12 nm in size, which is characteristic of nanoparticles. The images of SEM showed agglomeration of smaller ZnO-NPs and EDS authenticating that the synthesized nanoparticles were without impurities. The biosynthesized ZnO-NPs showed significant inhibition in the formation of AGEs. The particles were effective against methylglyoxal (MGO) mediated glycation of bovine serum albumin (BSA) by inhibiting the formation of AGEs, which was dose-dependent. Further, the presence of MGO resulted in complete damage of biconcave red blood corpuscles (RBCs) to an irregular shape, whereas the morphological changes were prevented when they were treated with ZnO-NPs leading to the prevention of complications caused due to glycation. The administration of ZnO-NPs (100 mg Kg−1) in streptozotocin(STZ)-induced diabetic rats reversed hyperglycemia and significantly improved hepatic enzymes level and renal functionality, also the histopathological studies revealed restoration of kidney and liver damage nearer to normal conditions. Molecular docking of BSA with ZnO-NPs confirms that masking of lysine and arginine residues is one of the possible mechanisms responsible for the potent antiglycation activity of ZnO-NPs. The findings strongly suggest scope for exploring the therapeutic potential of diabetes-related complications.Fil: Anandan, Satish. University of Mysore; IndiaFil: Mahadevamurthy, Murali. University of Mysore; IndiaFil: Ansari, Mohammad Azam. Imam Abdulrahman Bin Faisal University; Arabia SauditaFil: Alzohairy, Mohammad A.. Al Qassim University; Arabia SauditaFil: Alomary, Mohammad N.. King Abdulaziz City For Science And Technology; Arabia SauditaFil: Siraj, Syeda Farha. University of Mysore; IndiaFil: Nagaraja, Sarjan Halugudde. University of Mysore; IndiaFil: Chikkamadaiah, Mahendra. University of Mysore; IndiaFil: Ramachandrappa, Lakshmeesha Thimappa. University of Mysore; IndiaFil: Krishnappa, Hemanth Kumar Naguvanahalli. University of Mysore; IndiaFil: Ledesma, Ana Estela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet Noa Sur. Centro de Investigación en Biofísica Aplicada y Alimentos. - Universidad Nacional de Santiago del Estero. Centro de Investigación en Biofísica Aplicada y Alimentos; ArgentinaFil: Nagaraj, Amruthesh Kestur. University of Mysore; IndiaFil: Urooj, Asna. University of Mysore; Indi

    Comparative efficacy of two poeciliid fish in indoor cement tanks against chikungunya vector Aedes aegypti in villages in Karnataka, India

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    <p>Abstract</p> <p>Background</p> <p>In 2006, severe outbreaks of <it>Aedes aegypti</it>-transmitted chikungunya occurred in villages in Karnataka, South India. We evaluated the effectiveness of combined information, education and communication (IEC) campaigns using two potential poeciliid larvivorous fish guppy (<it>Poecilia reticulata</it>) and mosquitofish (<it>Gambusia affinis</it>), in indoor cement tanks for <it>Aedes </it>larval control.</p> <p>Methods</p> <p>Trials were conducted in two villages (Domatmari and Srinivaspura) in Tumkur District from March to May 2006 for <it>Poecilia </it>and one village (Balmanda) in Kolar District from July to October 2006 for <it>Gambusia</it>. A survey on knowledge, attitude and practice (KAP) on chikungunya was initially conducted and IEC campaigns were performed before and after fish release in Domatmari (IEC alone, followed by IEC + <it>Poecilia</it>) and Balmanda (IEC + <it>Gambusia</it>). In Srinivaspura, IEC was not conducted. Larval surveys were conducted at the baseline followed by one-week and one-month post-intervention periods. The impact of fish on <it>Aedes </it>larvae and disease was assessed based on baseline and post-intervention observations.</p> <p>Results</p> <p>Only 18% of respondents knew of the role of mosquitoes in fever outbreaks, while almost all (<it>n </it>= 50 each) gained new knowledge from the IEC campaigns. In Domatmari, IEC alone was not effective (OR 0.54; <it>p </it>= 0.067). Indoor cement tanks were the most preferred <it>Ae. aegypti </it>breeding habitat (86.9%), and had a significant impact on <it>Aedes </it>breeding (Breteau Index) in all villages in the one-week period (<it>p </it>< 0.001). In the one-month period, the impact was most sustained in Domatmari (OR 1.58, <it>p </it>< 0.001) then Srinivaspura (OR 0.45, <it>p </it>= 0.063) and Balmanda (OR 0.51, <it>p </it>= 0.067). After fish introductions, chikungunya cases were reduced by 99.87% in Domatmari, 65.48% in Srinivaspura and 68.51% in Balmanda.</p> <p>Conclusions</p> <p><it>Poecilia </it>exhibited greater survival rates than <it>Gambusia </it>(86.04 <it>vs</it>.16.03%) in cement tanks. Neither IEC nor <it>Poecilia </it>alone was effective against <it>Aedes </it>(<it>p </it>> 0.05). We conclude that <it>Poecilia </it>+ IEC is an effective intervention strategy. The operational cost was 0.50 (US0.011,1US 0.011, 1 US= 47) per capita per application. Proper water storage practices, focused IEC with <it>Poecilia </it>introductions and vector sanitation involving the local administration and community, is suggested as the best strategy for <it>Aedes </it>control.</p
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