A Holographic Entanglement Entropy at Spi

Defining finite entanglement entropy for a subregion in quantum field theory requires the introduction of two logically independent scales: an IR scale that controls the size of the subregion, and a UV cut-off. In AdS/CFT, the IR scale is the AdS lengthscale, the UV cut-off is the bulk radial cut-off, and the subregion is specified by dimensionless angles. This is the data that determines Ryu-Takayanagi surfaces and their areas in AdS/CFT. We argue that in asymptotically flat space there exists the notion of a "spi-subregion" that one can associate to spatial infinity (spi). Even though geometrically quite different from an AdS subregion, this angle data has the crucial feature that it allows an interpretation as a bi-partitioning of spi. Therefore, the area of the RT surface associated to the spi-subregion can be interpreted as the entanglement entropy of the reduced density matrix of the bulk state under this bi-partition, as in AdS/CFT. For symmetric spi-subregions, these RT surfaces are the waists of Asymptotic Causal Diamonds. In empty flat space they reduce to Rindler horizons, and are analogues of the AdS-Rindler horizons of Casini, Huerta \& Myers. We connect these definitions to previous work on minimal surfaces anchored to screens in empty space, but also generalize the discussion to the case where there are black holes in the bulk. The phases of black hole RT surfaces as the spi-subregion is varied, naturally connect with those of black holes (small and large) in AdS. A key observation is that the radial cut-off is associated to an IR scale in flat space -- and in fact there are no UV divergences. We argue that this is consistent with previous suggestions that in sub-AdS scales the holographic duality is an IR/IR correspondence and that the degrees of freedom are {\em not} those of a local QFT, but those of long strings. Strings are of course, famously UV finite.Comment: 55 pages, many plot

Hysteresis in hybrid perovskite indoor photovoltaics

L.K.J. acknowledges funding from UKRI-FLF through grant no MR/T022094/1.Halide perovskite indoor photovoltaics (PV) are a viable solution to autonomously power the billions of sensors in the huge technology field of the Internet of Things. However, there exists a knowledge gap in the hysteresis behaviour of these photovoltaic devices under indoor lighting conditions. The present work is the first experimental study dedicated to exploring the degree of hysteresis in halide perovskite indoor photovoltaic devices by carrying out both transient J-V scan and steady state maximum power point tracking (MPPT) measurements. Dependence of hysteresis on device architecture, selection of electron transporting layers and the composition of the perovskite photoactive layers were investigated. Under indoor illumination, the p-i-n MAPbI3-based devices show consistently high power conversion efficiency (PCE) (stabilized PCE) of greater than 30% and negligible hysteresis behaviour, whereas the n-i-p MAPbI3 devices show poor performance (stabilized PCE ∼ 15%) with pronounced hysteresis effect. Our study also reveals that the n-i-p triple cation perovskite devices are more promising (stabilized PCE ∼ 25%) for indoor PV compared to n-i-p MAPbI3 due to their suppressed ion migration effects. It was observed that the divergence of the PCE values estimated from the J-V scan measurements, and the maximum power point tracking method is higher under indoor illumination compared to 1 Sun, and hence for halide perovskite-based indoor PV, the PCE from the MPPT measurements should be prioritized over the J-V scan measurements. The results from our study suggest the following approaches for maximizing the steady state PCE from halide perovskite indoor PV: (i) select perovskite active layer composition with suppressed ion migration effects (such as Cs-containing triple cation perovskites) and (ii) for the perovskite composition such as MAPbI3, where the ion migration is very active, p-i-n architecture with organic charge transport layers is beneficial over the n-i-p architecture with conventional metal oxides (such as TiO2, SnO2) as charge transport layers. This article is part of the theme issue 'Developing resilient energy systems'.Publisher PDFPeer reviewe

First record of Chaetonotus (Primochaetus) heideri(Gastrotricha, Chaetonotida) from India

This study briefly reports a newly recorded gastrotrich species, Chaetonotus (Primochaetus) heideri Brehm, 1917, which was isolated from the water sample collected from the Ramsar site Khajjiar Lake, Himachal Pradesh, India. A brief description of the Indian population, based on photomicrographs taken from live specimens, is presented here. The species is reporte

Structure of cholest-5-en-3β-oxy-5-bromopentane by single-crystal X-ray diffraction at 130 K

Cholest-5-en-3β-oxy-5-bromopentane (1) and cholest-5-en-3β-oxy-11-bromoundecane (2), key precursors for the synthesis of novel cationic amphiphiles based on cholesterol, have been synthesized and characterized by 1H-NMR spectroscopy and X-ray crystallography. Thermal disorder and effect of length of the bromoalkyl segment on the crystal structure have been investigated. Possible molecular level explanation of the unusual alternating s-trans-gauche conformation of the bromopentyl side chain of (1) has been presented

The PNA–DNA hybrid I-motif: implications for sugar–sugar contacts in i-motif tetramerization

We have created a hybrid i-motif composed of two DNA and two peptide nucleic acid (PNA) strands from an equimolar mixture of a C-rich DNA and analogous PNA sequence. Nano-electrospray ionization mass spectrometry confirmed the formation of a tetrameric species, composed of PNA–DNA heteroduplexes. Thermal denaturation and CD experiments revealed that the structure was held together by C-H(+)-C base pairs. High resolution NMR spectroscopy confirmed that PNA and DNA form a unique complex comprising five C-H(+)-C base pairs per heteroduplex. The imino protons are protected from D(2)O exchange suggesting intercalation of the heteroduplexes as seen in DNA(4) i-motifs. FRET established the relative DNA and PNA strand polarities in the hybrid. The DNA strands were arranged antiparallel with respect to one another. The same topology was observed for PNA strands. Fluorescence quenching revealed that both PNA–DNA parallel heteroduplexes are intercalated, such that both DNA strands occupy one of the narrow grooves. H1′–H1′ NOEs show that both heteroduplexes are fully intercalated and that both DNA strands are disposed towards a narrow groove, invoking sugar–sugar interactions as seen in DNA(4) i-motifs. The hybrid i-motif shows enhanced thermal stability, intermediate pH dependence and forms at relatively low concentrations making it an ideal nanoscale structural element for pH-based molecular switches. It also serves as a good model system to assess the contribution of sugar–sugar contacts in i-motif tetramerization

Hospital-based surveillance of enteric parasites in Kolkata

<p>Abstract</p> <p>Background</p> <p>Diarrhoea is the second leading cause of illness and death in developing countries and the second commonest cause of death due to infectious diseases among children under five in such countries. Parasites, as well as bacterial and viral pathogens, are important causes of diarrhoea. However, parasitic infections are sometimes overlooked, leading after a period of time to an uncertain aetiology. In this paper we report the prevalence of <it>Giardia lamblia</it>, <it>Entamoeba histolytica </it>and <it>Cryptosporidium </it>sp. in and around Kolkata.</p> <p>Findings</p> <p>A hospital-based laboratory surveillance study was conducted among the patients admitted between November 2007 and October 2008 to the Infectious Diseases (ID) Hospital (Population = 1103) with diarrhoeal complaints. Of the 1103 samples collected, 147 were positive for <it>Giardia lamblia</it>, 84 for <it>Cryptosporidium </it>sp. and 51 for <it>Entamoeba histolytica</it>. For all these parasites there was a high rate of mixed infection with common enteric viruses and bacteria such as Rotavirus, <it>Vibrio cholerae </it>and <it>Shigella </it>sp. There were also cases of co-infection with all other diarrheogenic pathogens. The age group ≥ 5 years had the highest prevalence of parasites whereas the age group >5 – 10 years was predominantly infected with <it>Giardia lamblia </it>(p =< 0.001; Odds ratio (OR) = 3.937; 95% Confidence interval (CI) = 1.862 – 8.326) and with all parasites (p = 0.040; OR = 2.043; 95% CI = 1.033 – 4.039). The age group >10 – 20 years could also be considered at risk for <it>G. lamblia </it>(p = 0.009; OR = 2.231; 95% CI = 1.223 – 4.067). Month-wise occurrence data showed an endemic presence of <it>G. lamblia </it>whereas <it>Cryptosporidium </it>sp. and <it>E. histolytica </it>occurred sporadically. The GIS study revealed that parasites were more prevalent in areas such as Tangra, Tiljala and Rajarhat, which are mainly slum areas. Because most of the population surveyed was in the lower income group, consumption of contaminated water and food could be the major underlying cause of parasitic infestations.</p> <p>Conclusion</p> <p>This study provides important information on the occurrence and distribution of three important intestinal parasites and indicates their diarrheogenic capacity in Kolkata and surrounding areas.</p

Size-tunable hydrophilic cerium oxide nanoparticles as a `turn-on' fluorescence sensor for the rapid detection of ultralow concentrations of vitamin C

The novel perspective of cerium dioxide as a fluorescence sensor has been demonstrated in the present study. The green coloured emission associated with the nano-dimensions of ceria has been adopted as an analytical tool to sense vitamin C, which is a biologically important molecule, in dilute concentrations. Ultrafine ceria nanoparticles of average size 2.2 nm have been fabricated by a surfactant assisted thermal decomposition strategy. The particular fashion of attachment of the oleic acid surfactant with ceria resulted in the surface hydrophobicity of the nanoparticles which in turn prevents their interaction with a hydrophilic molecule like vitamin C in the reaction media. In order to tackle the incompatibility of the nanoparticles with water, a hydrophilic surfactant coating has been grafted over their surface via bilayer surface functionalisation. The success of the accomplished strategy has been confirmed by thermogravimetric analyses, zeta potential and contact angle measurements. The redox properties of ceria and its optical properties served as a probe to quantify vitamin C in the concentration range 10(-7) to 10(-4) M with a very low limit of detection (LoD) of 500 nM. The designed sensor exhibits a rapid `turn on' fluorescence response within 30 seconds and the reversibility of its fluorescence even after 5 cycles of vitamin C addition corroborates its reusability. The high selectivity of the sensor to detect vitamin C again highlights its suitability as an analytical tool. The realistic application of the sensor has also been displayed by the quantification of vitamin C in pharmaceutical formulations within acceptable error limits

Emerging trends in the etiology of enteric pathogens as evidenced from an active surveillance of hospitalized diarrhoeal patients in Kolkata, India

Background: This study was conducted to determine the etiology of diarrhoea in a hospital setting in Kolkata. Active surveillance was conducted for 2 years on two random days per week by enrolling every fifth diarrhoeal patient admitted to the Infectious Diseases and Beliaghata General Hospital in Kolkata. Results: Most of the patients (76.1%) had acute watery diarrhoea in association with vomiting (77.7%) and some dehydration (92%). Vibrio cholerae O1, Rotavirus and Giardia lamblia were the important causes of diarrhoea. Among Shigella spp, S. flexneri 2a and 3a serotypes were most predominantly isolated. Enteric viruses, EPEC and EAEC were common in children <5 year age group. Atypical EPEC was comparatively higher than the typical EPEC. Multidrug resistance was common among V. cholerae O1 and Shigella spp including tetracycline and ciprofloxacin. Polymicrobial infections were common in all age groups and 27.9% of the diarrhoea patients had no potential pathogen. Conclusions: Increase in V. cholerae O1 infection among <2 years age group, resistance of V. cholerae O1 to tetracycline, rise of untypable S. flexnerii, higher proportion of atypical EPEC and G. lamblia and polymicrobial etiology are some of the emerging trends observed in this diarrhoeal disease surveillance