91 research outputs found
ABCD of Beta Ensembles and Topological Strings
We study beta-ensembles with Bn, Cn, and Dn eigenvalue measure and their
relation with refined topological strings. Our results generalize the familiar
connections between local topological strings and matrix models leading to An
measure, and illustrate that all those classical eigenvalue ensembles, and
their topological string counterparts, are related one to another via various
deformations and specializations, quantum shifts and discrete quotients. We
review the solution of the Gaussian models via Macdonald identities, and
interpret them as conifold theories. The interpolation between the various
models is plainly apparent in this case. For general polynomial potential, we
calculate the partition function in the multi-cut phase in a perturbative
fashion, beyond tree-level in the large-N limit. The relation to refined
topological string orientifolds on the corresponding local geometry is
discussed along the way.Comment: 33 pages, 1 figur
Automated Analysis of Large-Scale NMR Data Generates Metabolomic Signatures and Links Them to Candidate Metabolites.
Identification of metabolites in large-scale <sup>1</sup> H NMR data from human biofluids remains challenging due to the complexity of the spectra and their sensitivity to pH and ionic concentrations. In this work, we tested the capacity of three analysis tools to extract metabolite signatures from 968 NMR profiles of human urine samples. Specifically, we studied sets of covarying features derived from principal component analysis (PCA), the iterative signature algorithm (ISA), and averaged correlation profiles (ACP), a new method we devised inspired by the STOCSY approach. We used our previously developed metabomatching method to match the sets generated by these algorithms to NMR spectra of individual metabolites available in public databases. On the basis of the number and quality of the matches, we concluded that ISA and ACP can robustly identify ten and nine metabolites, respectively, half of which were shared, while PCA did not produce any signatures with robust matches
Orientifolds and the Refined Topological String
We study refined topological string theory in the presence of orientifolds by
counting second-quantized BPS states in M-theory. This leads us to propose a
new integrality condition for both refined and unrefined topological strings
when orientifolds are present. We define the SO(2N) refined Chern-Simons theory
which computes refined open string amplitudes for branes wrapping Seifert
three-manifolds. We use the SO(2N) refined Chern-Simons theory to compute new
invariants of torus knots that generalize the Kauffman polynomials. At large N,
the SO(2N) refined Chern-Simons theory on the three-sphere is dual to refined
topological strings on an orientifold of the resolved conifold, generalizing
the Gopakumar-Sinha-Vafa duality. Finally, we use the (2,0) theory to define
and solve refined Chern-Simons theory for all ADE gauge groups
Decoupling A and B model in open string theory -- Topological adventures in the world of tadpoles
In this paper we analyze the problem of tadpole cancellation in open
topological strings. We prove that the inclusion of unorientable worldsheet
diagrams guarantees a consistent decoupling of A and B model for open
superstring amplitudes at all genera. This is proven by direct microscopic
computation in Super Conformal Field Theory. For the B-model we explicitly
calculate one loop amplitudes in terms of analytic Ray-Singer torsions of
appropriate vector bundles and obtain that the decoupling corresponds to the
cancellation of D-brane and orientifold charges. Local tadpole cancellation on
the worldsheet then guarantees the decoupling at all loops. The holomorphic
anomaly equations for open topological strings at one loop are also obtained
and compared with the results of the Quillen formula
General Omega Deformations from Closed String Backgrounds
In this note, an important extension to the recent construction of the
fluxtrap background is presented. The fluxtrap is a closed string background
based on the Melvin solution corresponding to the Omega deformation of flat
space. In this note, we introduce the mechanisms to extend it from
epsilon_1=-epsilon_2 in R to more general values of epsilon_1 and epsilon_2 in
C.Comment: 12 pages. Typos corrected, some clarifications in text. Version
accepted for publication in JHE
Extended Holomorphic Anomaly in Gauge Theory
The partition function of an N=2 gauge theory in the Omega-background
satisfies, for generic value of the parameter beta=-eps_1/eps_2, the, in
general extended, but otherwise beta-independent, holomorphic anomaly equation
of special geometry. Modularity together with the (beta-dependent) gap
structure at the various singular loci in the moduli space completely fixes the
holomorphic ambiguity, also when the extension is non-trivial. In some cases,
the theory at the orbifold radius, corresponding to beta=2, can be identified
with an "orientifold" of the theory at beta=1. The various connections give
hints for embedding the structure into the topological string.Comment: 25 page
Calculations for Mirror Symmetry with D-branes
We study normal functions capturing D-brane superpotentials on several one-
and two-parameter Calabi-Yau hypersurfaces and complete intersections in
weighted projective space. We calculate in the B-model and interpret the
results using mirror symmetry in the large volume regime, albeit without
identifying the precise A-model geometry in all cases. We identify new classes
of extensions of Picard-Fuchs equations, as well as a novel type of topology
changing phase transition involving quantum D-branes. A 4-d domain wall which
is obtained in one region of closed string moduli space from wrapping a
four-chain interpolating between two Lagrangian submanifolds is, for other
values of the parameters, represented by a disk ending on a single Lagrangian.Comment: 42 page
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