960 research outputs found

    The Lisbon review: Business plan for a lifestyle & art magazine

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    This business plan evaluates the possibility of establishing a special interest publication in the market of print magazines with a combination of themes in lifestyle, art and literature. It attempts to combine modern tendencies and timeless values, collectively implemented through a foreseen market opportunity, approved by the outcomes of this business plan analyses. Therefore, communicational theories have been applied and tools, acquired throughout the master studies, have been utilized in order to do so. Furthermore, this paper draws a cross section through the market, by giving insights on market dynamics, risks and chances. Conclusively it states, what it takes to create an economic successful publication in the world of crumbling magazine and newspaper circulations. Right here this Business Plan is aiming to create a correlation between credibility and prestige in order to guarantee economic efficiency. Knowing what that takes, targets can be defined, strategies can be developed and integrated into a financial plan, which, last but not least, is giving a confident outlook for the defined product and its selected market.Este plano de negócios avalia a possibilidade de estabelecer uma publicação de interesse especial no mercado de revistas impressas com uma combinação de temas em estilo de vida, arte e literatura. Ele tenta combinar tendências modernas e valores atemporais, implementados coletivamente por meio de uma oportunidade de mercado prevista, aprovada pelos resultados desta análise do plano de negócios. Portanto, teorias comunicacionais foram aplicadas e ferramentas adquiridas ao longo dos estudos de mestrado foram utilizadas para isso. Além disso, este artigo apresenta uma seção transversal do mercado, fornecendo informações sobre a dinâmica, riscos e chances do mercado. Em conclusão, ele afirma o que é preciso para criar uma publicação de sucesso econômico no mundo das circulações de revistas e jornais em ruínas. Aqui, este plano de negócios tem como objetivo criar uma correlação entre credibilidade e prestígio, a fim de garantir eficiência econômica. Sabendo o que é necessário, as metas podem ser definidas, as estratégias podem ser desenvolvidas e integradas a um plano financeiro que, por último, mas não menos importante, oferece uma visão confiante do produto definido e do mercado selecionado

    The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling

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    Motivation: Homology models of proteins are of great interest for planning and analysing biological experiments when no experimental three-dimensional structures are available. Building homology models requires specialized programs and up-to-date sequence and structural databases. Integrating all required tools, programs and databases into a single web-based workspace facilitates access to homology modelling from a computer with web connection without the need of downloading and installing large program packages and databases. Results: SWISS-MODEL workspace is a web-based integrated service dedicated to protein structure homology modelling. It assists and guides the user in building protein homology models at different levels of complexity. A personal working environment is provided for each user where several modelling projects can be carried out in parallel. Protein sequence and structure databases necessary for modelling are accessible from the workspace and are updated in regular intervals. Tools for template selection, model building and structure quality evaluation can be invoked from within the workspace. Workflow and usage of the workspace are illustrated by modelling human Cyclin A1 and human Transmembrane Protease 3. Availability: The SWISS-MODEL workspace can be accessed freely at Contact: [email protected] Supplementary information: Supplementary data are available at Bioinformatics onlin

    The SWISS-MODEL Repository and associated resources

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    SWISS-MODEL Repository (http://swissmodel.expasy.org/repository/) is a database of 3D protein structure models generated by the SWISS-MODEL homology-modelling pipeline. The aim of the SWISS-MODEL Repository is to provide access to an up-to-date collection of annotated 3D protein models generated by automated homology modelling for all sequences in Swiss-Prot and for relevant models organisms. Regular updates ensure that target coverage is complete, that models are built using the most recent sequence and template structure databases, and that improvements in the underlying modelling pipeline are fully utilised. As of September 2008, the database contains 3.4 million entries for 2.7 million different protein sequences from the UniProt database. SWISS-MODEL Repository allows the users to assess the quality of the models in the database, search for alternative template structures, and to build models interactively via SWISS-MODEL Workspace (http://swissmodel.expasy.org/workspace/). Annotation of models with functional information and cross-linking with other databases such as the Protein Model Portal (http://www.proteinmodelportal.org) of the PSI Structural Genomics Knowledge Base facilitates the navigation between protein sequence and structure resource

    Eine Konzeption des Produktmanagement in Nonprofit-Organisationen

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    Nonprofit-Organisationen sind gerade aufgrund ihrer Stellung zwischen Markt und Staat auf eine systematische Informationswirtschaft im Rahmen ihres Produktmanagement angewiesen. Insbesondere die Beschaffung, Aufbereitung und Umsetzung von Informationen über die Ansprüche marktlicher und nichtmarktlicher Kundengruppen zählt zu den wesentlichen Aufgaben des Nonprofit-Managements. Die betriebliche Produktmarktforschung in Nonprofit-Organisationen kann dazu beitragen, die Ausrichtung der Unternehmenspolitik auf den Ausbau und die Festigung der vielfältigen Kundenbeziehungen zu stärken. Nur auf diese Weise können Entscheidungsträger in NPO sicherstellen, daß sie die notwendigen Verflechtungen mit dem Markt intensivieren, Wettbewerbsvorteile gegenüber anderen Leistungsanbietern erlangen und die NPO sich selbst als leistungsfähiger und legitimer Teil unserer Gesellschaftsordnung behaupten kann

    The SWISS-MODEL Repository and associated resources

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    SWISS-MODEL Repository (http://swissmodel.expasy.org/repository/) is a database of 3D protein structure models generated by the SWISS-MODEL homology-modelling pipeline. The aim of the SWISS-MODEL Repository is to provide access to an up-to-date collection of annotated 3D protein models generated by automated homology modelling for all sequences in Swiss-Prot and for relevant models organisms. Regular updates ensure that target coverage is complete, that models are built using the most recent sequence and template structure databases, and that improvements in the underlying modelling pipeline are fully utilised. As of September 2008, the database contains 3.4 million entries for 2.7 million different protein sequences from the UniProt database. SWISS-MODEL Repository allows the users to assess the quality of the models in the database, search for alternative template structures, and to build models interactively via SWISS-MODEL Workspace (http://swissmodel.expasy.org/workspace/). Annotation of models with functional information and cross-linking with other databases such as the Protein Model Portal (http://www.proteinmodelportal.org) of the PSI Structural Genomics Knowledge Base facilitates the navigation between protein sequence and structure resources

    Solvability of the Hamiltonians related to exceptional root spaces: rational case

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    Solvability of the rational quantum integrable systems related to exceptional root spaces G2,F4G_2, F_4 is re-examined and for E6,7,8E_{6,7,8} is established in the framework of a unified approach. It is shown the Hamiltonians take algebraic form being written in a certain Weyl-invariant variables. It is demonstrated that for each Hamiltonian the finite-dimensional invariant subspaces are made from polynomials and they form an infinite flag. A notion of minimal flag is introduced and minimal flag for each Hamiltonian is found. Corresponding eigenvalues are calculated explicitly while the eigenfunctions can be computed by pure linear algebra means for {\it arbitrary} values of the coupling constants. The Hamiltonian of each model can be expressed in the algebraic form as a second degree polynomial in the generators of some infinite-dimensional but finitely-generated Lie algebra of differential operators, taken in a finite-dimensional representation.Comment: 51 pages, LaTeX, few equations added, one reference added, typos correcte
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