Novel Relations between Lepton and Quark Mixings

A novel relation is found which gives the 2-3 lepton mixing angle in terms of quark masses and CKM mixing: \tan\theta_{\mu\tau}=(m_b/m_s)V_{cb}. This relation, which is remarkably in good agreement with the quark data and the large lepton mixing recently observed, is a kind of SO(10) GUT relation similar to the celebrated bottom-tau mass ratio in SU(5). The GUT models in which this relation hold should have a `twisted SO(10)' structure between the second and third generations, in order to really explain the large lepton mixing, or equivalently, the right-hand side of the relation.Comment: 8 pages, typos correcte

Asynchronous Rhythm of Steroidogenic Factor 1 and Period Homolog 2 mRNA Expression in Mouse Y1 Adrenocorticol Tumor Cells

The relationship between the expression of Steroidogenic factor 1 (Sf1) and the circadian-related gene, period homolog 2 (Per2), in the adrenal cortex is still unknown. We show here that in Y1 adrenocortical tumor cells, expression of steroidogenic-related genes such as P450scc mRNA and Sf1 mRNA were asynchronous with Per2 mRNA. SF1 promoter analyses showed that the E-box element functions in a rhythmic pattern. Rhythmic expression of Upstream factor 1 mRNA, correlated well with Sf1 mRNA expression. We propose that tumorigenesis of adrenocortical lesions cause disruption of synchronous expression of steroidogenic-related and circadian-related genes