CAIO FERNANDO ABREU POR CAIO F.

Pretende-se analisar a obra literária de Caio Fernando Abreu (CFA) pela perspectiva da escrita de si (auto e/ou alterficcional) e da performance, por duas faces: a dos viajantes (em constantes deslocamentos de personagens em contiguidade às viagens do autor) e a das personae, sobretudo, as verificadas nas cartas em que CFA embaralha outros de si, assinando diferentes nomes, como Caio F. A estrutura é análoga a um roteiro de viagem. As duas faces estudadas culminam num Diário de bordo, com fragmentos de romances, contos, cartas, crônicas e entrevistas do escritor a periódicos. O Diário é assinado por Caio F., o outro de si que triunfa como rastro do rastro, a marca da escrita, o representante, a persona mais iterável que, cada vez mais substitui e/ou sobrepõe o nome do autor, mesmo após as mais de três décadas da sua criação

Sclerite formation in the hydrothermal-vent “scaly-foot” gastropod — possible control of iron sulfide biomineralization by the animal

A gastropod from a deep-sea hydrothermal field at the Rodriguez triple junction, Indian Ocean, has scale-shaped structures, called sclerites, mineralized with iron sulfides on its foot. No other organisms are known to produce a skeleton consisting of iron sulfides. To investigate whether iron sulfide mineralization is mediated by the gastropod for the function of the sclerites, we performed a detailed physical and chemical characterization. Nanostructural characterization of the iron sulfide sclerites reveals that the iron sulfide minerals pyrite (FeS2) and greigite (Fe3S4) form with unique crystal habits inside and outside of the organic matrix, respectively. The magnetic properties of the sclerites, which are mostly consistent with those predicted from their nanostructual features, are not optimized for magnetoreception and instead support use of the magnetic minerals as structural elements. The mechanical performance of the sclerites is superior to that of other biominerals used in the vent environment for predation as well as protection from predation. These characteristics, as well as the co-occurrence of brachyuran crabs, support the inference that the mineralization of iron sulfides might be controlled by the gastropod to harden the sclerites for protection from predators. Sulfur and iron isotopic analyses indicate that sulfur and iron in the sclerites originate from hydrothermal fluids rather than from bacterial metabolites, and that iron supply is unlikely to be regulated by the gastropod for iron sulfide mineralization. We propose that the gastropod may control iron sulfide mineralization by modulating the internal concentrations of reduced sulfur compounds

Discovery of a new photometric sub-class of faint and fast classical novae

We present photometric and spectroscopic follow-up of a sample of extragalactic novae discovered by the Palomar 60-inch telescope during a search for "Fast Transients In Nearest Galaxies" (P60-FasTING). Designed as a fast cadence (1-day) and deep (g < 21 mag) survey, P60-FasTING was particularly sensitive to short-lived and faint optical transients. The P60-FasTING nova sample includes 10 novae in M31, 6 in M81, 3 in M82, 1 in NGC2403 and 1 in NGC891. This significantly expands the known sample of extragalactic novae beyond the Local Group, including the first discoveries in a starburst environment. Surprisingly, our photometry shows that this sample is quite inconsistent with the canonical Maximum Magnitude Rate of Decline (MMRD) relation for classical novae. Furthermore, the spectra of the P60-FasTING sample are indistinguishable from classical novae. We suggest that we have uncovered a sub-class of faint and fast classical novae in a new phase space in luminosity-timescale of optical transients. Thus, novae span two orders of magnitude in both luminosity and time. Perhaps, the MMRD, which is characterized only by the white dwarf mass, was an over-simplification. Nova physics appears to be characterized by quite a rich four-dimensional parameter space in white dwarf mass, temperature, composition and accretion rate.Comment: Submitted to ApJ, 12 pages. High resolution version at http://www.astro.caltech.edu/~mansi/msFasting.pd

The CIDA Variability Survey of Orion OB1. I: the low-mass population of Ori OB 1a and 1b

We present results of a large scale, multi-epoch optical survey of the Ori OB1 association, carried out with the QuEST camera at the Venezuela National Astronomical Observatory. We identify for the first time the widely spread low-mass, young population in the Orion OB1a and OB1b sub-associations. Candidate members were picked up by their variability in the V-band and position in color-magnitude diagrams. We obtained spectra to confirm membership. In a region spanning ~ 68 deg^2 we found 197 new young stars; of these, 56 are located in the Ori OB1a subassociation and 142 in Ori OB1b. Comparison with the spatial extent of molecular gas and extinction maps indicates that the subassociation Ori 1b is concentrated within a ring-like structure of radius ~2 deg (~15 pc at 440 pc), centered roughly on the star epsilon Ori in the Orion belt. The ring is apparent in 13CO and corresponds to a region with an extinction Av>=1. The stars exhibiting strong Ha emission, an indicator of active accretion, are found along this ring, while the center is populated with weak Ha emitting stars. In contrast, Ori OB1a is located in a region devoid of gas and dust. We identify a grouping of stars within a ~3 deg^2 area located in 1a, roughly clustered around the B2 star 25 Ori. The Herbig Ae/Be star V346 Ori is also associated with this grouping, which could be an older analog of sigma Ori. Using using several sets of evolutionary tracks we find an age of 7 - 10 Myr for Ori 1a and of ~4 - 6 Myr for Ori OB1b, consistent with previous estimates from OB stars. Indicators such as the equivalent width of Ha and near-IR excesses show that while a substantial fraction of accreting disks remain at ages ~5 Myr, inner disks are essentially dissipated by 10 Myr.Comment: 44 pages, 12 figures, to appear in the Astronomical Journal. (Abridged abstract - to fit length limit in astroph) Full resolution figures in http://www.cida.ve/~briceno/publications

Rotational velocities of A-type stars. III. Velocity distributions

Aim - In this work, a sample of vsini of B9 to F2-type main sequence single stars has been built from highly homogeneous vsini parameters determined for a large sample cleansed from objects presenting the Am and Ap phenomenon as well as from all known binaries. The aim is to study the distributions of rotational velocities in the mass range of A-type stars for normal single objects. Methods - Robust statistical methods are used to rectify the vsini distributions from the projection effect and the error distribution. The equatorial velocity distributions are obtained for an amount of about 1100 stars divided in six groups defined by the spectral type, under the assumption of randomly orientated rotational axes. Results - We show that late B and early A-type main-sequence stars have genuine bimodal distributions of true equatorial rotational velocities due probably to phenomena of angular momentum loss and redistribution the star underwent before reaching the main sequence. A striking lack of slow rotators is noticed among intermediate and late A-type stars. The bimodal-like shape of their true equatorial rotational velocity distributions could be due to evolutionary effects.Comment: 16 pages, 10 figures, accepted in A&

A Search for Very Low-mass Stars and Brown Dwarfs in the Young sigma Orionis Cluster

We present a CCD-based photometric survey covering 870 sq. arcmin in a young stellar cluster around the young multiple star sigma Orionis. Our survey limiting R, I, and Z magnitudes are 23.2, 21.8, and 21.0, respectively. From our colour-magnitude diagrams, we have selected 49 faint objects, which smoothly extrapolate the photometric sequence defined by more massive known members. Adopting the currently accepted age interval of 2-10 Myr for the Orion 1b association and considering recent evolutionary models, our objects may span a mass range from 0.1 down to 0.02 Msun, well within the substellar regime. Follow-up low-resolution optical spectroscopy (635-920 nm) for eight of our candidates (I=16-19.5) shows that they have spectral types M6-M8.5 which are consistent with the expectations for true members. Compared with their Pleiades counterparts of similar types, Halpha emission is generally stronger, while NaI and KI absorption lines appear weaker, as expected for lower surface gravities and younger ages. Additionally, TiO bands and in particular VO bands appear clearly enhanced in our candidate with the latest spectral type, SOri 45 (M8.5, I=19.5), compared to objects of similar types in older clusters and the field. We have estimated the mass of this candidate at only 0.020-0.040 Msun, hence it is one of the least massive brown dwarfs yet discovered. We also discuss in this paper the potential role of deuterium as a tracer of both substellar nature and age in very young clusters.Comment: Accepted for publication in ApJ Main Journal. 32 pages of text and tables + 9 pages of figures. Figures 3a and 3b (gif format) provided separatel

Microguards and micromessengers of the genome

The regulation of gene expression is of fundamental importance to maintain organismal function and integrity and requires a multifaceted and highly ordered sequence of events. The cyclic nature of gene expression is known as ‘transcription dynamics’. Disruption or perturbation of these dynamics can result in significant fitness costs arising from genome instability, accelerated ageing and disease. We review recent research that supports the idea that an important new role for small RNAs, particularly microRNAs (miRNAs), is in protecting the genome against short-term transcriptional fluctuations, in a process we term ‘microguarding’. An additional emerging role for miRNAs is as ‘micromessengers’—through alteration of gene expression in target cells to which they are trafficked within microvesicles. We describe the scant but emerging evidence that miRNAs can be moved between different cells, individuals and even species, to exert biologically significant responses. With these two new roles, miRNAs have the potential to protect against deleterious gene expression variation from perturbation and to themselves perturb the expression of genes in target cells. These interactions between cells will frequently be subject to conflicts of interest when they occur between unrelated cells that lack a coincidence of fitness interests. Hence, there is the potential for miRNAs to represent both a means to resolve conflicts of interest, as well as instigate them. We conclude by exploring this conflict hypothesis, by describing some of the initial evidence consistent with it and proposing new ideas for future research into this exciting topic

Social presence and dishonesty in retail

Self-service checkouts (SCOs) in retail can benefit consumers and retailers, providing control and autonomy to shoppers independent from staff, together with reduced queuing times. Recent research indicates that the absence of staff may provide the opportunity for consumers to behave dishonestly, consistent with a perceived lack of social presence. This study examined whether a social presence in the form of various instantiations of embodied, visual, humanlike SCO interface agents had an effect on opportunistic behaviour. Using a simulated SCO scenario, participants experienced various dilemmas in which they could financially benefit themselves undeservedly. We hypothesised that a humanlike social presence integrated within the checkout screen would receive more attention and result in fewer instances of dishonesty compared to a less humanlike agent. This was partially supported by the results. The findings contribute to the theoretical framework in social presence research. We concluded that companies adopting self-service technology may consider the implementation of social presence in technology applications to support ethical consumer behaviour, but that more research is required to explore the mixed findings in the current study.<br/

Use of fuzzy edge single-photon emission computed tomography analysis in definite Alzheimer's disease - a retrospective study

<p>Abstract</p> <p>Background</p> <p>Definite Alzheimer's disease (AD) requires neuropathological confirmation. Single-photon emission computed tomography (SPECT) may enhance diagnostic accuracy, but due to restricted sensitivity and specificity, the role of SPECT is largely limited with regard to this purpose.</p> <p>Methods</p> <p>We propose a new method of SPECT data analysis. The method is based on a combination of parietal lobe selection (as regions-of-interest (ROI)), 3D fuzzy edge detection, and 3D watershed transformation. We applied the algorithm to three-dimensional SPECT images of human brains and compared the number of watershed regions inside the ROI between AD patients and controls. The Student's two-sample t-test was used for testing domain number equity in both groups.</p> <p>Results</p> <p>AD patients had a significantly reduced number of watershed regions compared to controls (<it>p </it>< 0.01). A sensitivity of 94.1% and specificity of 80% was obtained with a threshold value of 57.11 for the watershed domain number. The narrowing of the SPECT analysis to parietal regions leads to a substantial increase in both sensitivity and specificity.</p> <p>Conclusions</p> <p>Our non-invasive, relatively low-cost, and easy method can contribute to a more precise diagnosis of AD.</p

Direct Observation of Dimerization between Different CREB1 Isoforms in a Living Cell

Cyclic AMP-responsive element binding protein 1 (CREB1) plays multiple functions as a transcription factor in gene regulation. CREB1 proteins are also known to be expressed in several spliced isoforms that act as transcriptional activators or repressors. The activator isoforms, possessing the functional domains for kinase induction and for interaction with other transcriptional regulators, act as transcriptional activators. On the other hand, some isoforms, lacking those functional domains, are reported to be repressors that make heterodimers with activator isoforms. The complex and ingenious function for CREB1 arises in part from the variation in their spliced isoforms, which allows them to interact with each other. To date, however, the dimerization between the activator and repressor isoforms has not yet been proved directly in living cells. In this study, we applied fluorescence cross-correlation spectroscopy (FCCS) to demonstrate direct observation of dimerization between CREB1 activator and repressor. The FCCS is a well established spectroscopic method to determine the interaction between the different fluorescent molecules in the aqueous condition. Using differently labeled CREB1 isoforms, we successfully observed the interaction of CREB1 activator and repressor via dimerization in the nuclei of cultured cells. As a result, we confirmed the formation of heterodimer between CREB1 activator and repressor isoforms in living cells