934 research outputs found

    Cryptanalysis of group-based key agreement protocols using subgroup distance functions

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    We introduce a new approach for cryptanalysis of key agreement protocols based on noncommutative groups. This approach uses functions that estimate the distance of a group element to a given subgroup. We test it against the Shpilrain-Ushakov protocol, which is based on Thompson's group F

    The groupoidal analogue Theta~ to Joyal's category Theta is a test category

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    We introduce the groupoidal analogue \tilde\Theta to Joyal's cell category \Theta and we prove that \tilde\Theta is a strict test category in the sense of Grothendieck. This implies that presheaves on \tilde\Theta model homotopy types in a canonical way. We also prove that the canonical functor from \Theta to \tilde\Theta is aspherical, again in the sense of Grothendieck. This allows us to compare weak equivalences of presheaves on \tilde\Theta to weak equivalences of presheaves on \Theta. Our proofs apply to other categories analogous to \Theta.Comment: 41 pages, v2: references added, Remark 7.3 added, v3: metadata update

    Evaluation of an Artificial Intelligence Coronary Artery Calcium Scoring Model from Computed Tomography

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    OBJECTIVES: Coronary artery calcium (CAC) scores derived from computed tomography (CT) scans are used for cardiovascular risk stratification. Artificial intelligence (AI) can assist in CAC quantification and potentially reduce the time required for human analysis. This study aimed to develop and evaluate a fully automated model that identifies and quantifies CAC. METHODS: Fully convolutional neural networks for automated CAC scoring were developed and trained on 2439 cardiac CT scans and validated using 771 scans. The model was tested on an independent set of 1849 cardiac CT scans. Agatston CAC scores were further categorised into five risk categories (0, 1–10, 11–100, 101–400, and > 400). Automated scores were compared to the manual reference standard (level 3 expert readers). RESULTS: Of 1849 scans used for model testing (mean age 55.7 ± 10.5 years, 49% males), the automated model detected the presence of CAC in 867 (47%) scans compared with 815 (44%) by human readers (p = 0.09). CAC scores from the model correlated very strongly with the manual score (Spearman’s r = 0.90, 95% confidence interval [CI] 0.89–0.91, p < 0.001 and intraclass correlation coefficient = 0.98, 95% CI 0.98–0.99, p < 0.001). The model classified 1646 (89%) into the same risk category as human observers. The Bland–Altman analysis demonstrated little difference (1.69, 95% limits of agreement: −41.22, 44.60) and there was almost excellent agreement (Cohen’s κ = 0.90, 95% CI 0.88–0.91, p < 0.001). Model analysis time was 13.1 ± 3.2 s/scan. CONCLUSIONS: This artificial intelligence–based fully automated CAC scoring model shows high accuracy and low analysis times. Its potential to optimise clinical workflow efficiency and patient outcomes requires evaluation. KEY POINTS: • Coronary artery calcium (CAC) scores are traditionally assessed using cardiac computed tomography and require manual input by human operators to identify calcified lesions. • A novel artificial intelligence (AI)–based model for fully automated CAC scoring was developed and tested on an independent dataset of computed tomography scans, showing very high levels of correlation and agreement with manual measurements as a reference standard. • AI has the potential to assist in the identification and quantification of CAC, thereby reducing the time required for human analysis. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00330-022-09028-3

    Fear of the unknown: a pre-departure qualitative study of Turkish international students

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    This paper presents findings from eleven in-depth interviews with Turkish undergraduate students, who were, by the time of data collection, about to spend a semester at a European university under the Erasmus exchange scheme. The students all agreed to be interviewed about their feelings about studying in a foreign culture, and were found to be anxious prior to departure about the quality of accommodation in the new destination, their language ability and the opportunity to form friendships. Fears were expressed about possible misconceptions over Turkey as a Muslim and a developing country. Suggestions are made for HEI interventions to allay student travellers’ concerns

    Role of baryonic resonances in the dilepton emission in nucleon-nucleon collisions

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    Within an effective Lagrangian model, we present calculations for cross sections of the dilepton production in proton-proton and proton-neutron collisions at laboratory kinetic energies in 1-5 GeV range. Production amplitudes include contributions from the nucleon-nucleon bremsstrahlung as well as from the mechanism of excitation, propagation, and radiative decay of Delta(1232) and N*(1520) intermediate baryonic resonances. It is found that the delta isobar terms dominate the cross sections in the entire considered beam energy range. Our calculations are able to explain the data of the DLS collaboration on the dilepton production in proton-proton collisions for beam energies below 1.3 GeV. However, for incident energies higher than this the inclusion of contributions from other dilepton sources like Dalitz decay of pi0 and eta mesons, and direct decay of rho and omega mesons is necessary to describe the data.Comment: 22 pages, 7 figures, more details of the calculations added, version to appear in Phys. Rev

    A systematic review of health-related quality of life in cutaneous melanoma

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    Melanoma can be considered an emerging chronic disease that may considerably affect patients’ lives. The authors systematically reviewed the available literature on health-related quality of life (HRQOL) and melanoma. Of reviews and the selected studies, reference lists were hand-searched. The quality of the eligible studies was appraised based on 14 previously published criteria. Of the 158 abstracts, 44 articles were appraised, resulting in 13 selected studies written in English (published between 2001 and 2008). Most studies assessed patients from specialised centres with varying, but relatively advanced, disease stages. The most commonly used instruments were the SF-36 and EORTC QLQ-C30. Recently, a melanoma-specific HRQOL questionnaire [FACT-Melanoma (FACT-M)] was introduced for clinical trial purposes. It showed that approximately one-third of melanoma patients experienced considerable levels of distress, mostly at the time of diagnosis and following treatment. Systemic therapies affected HRQOL negatively in the short term, but to a lesser extent in the long term. Health status and patients’ psychological characteristics are associated with higher levels of HRQOL impairment. The authors found that the impact of melanoma on patients’ HRQOL is comparable to that of other cancers. Accurately assessing HRQOL impairment in melanoma patients is pivotal, as it may affect disease management, including therapy and additional counselling, future preventive behaviour and perhaps even prognosis

    Hadronic observables from SIS to SPS energies - anything strange with strangeness ?

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    We calculate p,π±,K±p, \pi^\pm, K^\pm and Λ\Lambda(+Σ0\Sigma^0) rapidity distributions and compare to experimental data from SIS to SPS energies within the UrQMD and HSD transport approaches that are both based on string, quark, diquark (q,qˉ,qq,qˉqˉq, \bar{q}, qq, \bar{q}\bar{q}) and hadronic degrees of freedom. The two transport models do not include any explicit phase transition to a quark-gluon plasma (QGP). It is found that both approaches agree rather well with each other and with the experimental rapidity distributions for protons, Λ\Lambda's, π±\pi^\pm and K±K^\pm. Inspite of this apparent agreement both transport models fail to reproduce the maximum in the excitation function for the ratio K+/π+K^+/\pi^+ found experimentally between 11 and 40 A\cdotGeV. A comparison to the various experimental data shows that this 'failure' is dominantly due to an insufficient description of pion rapidity distributions rather than missing 'strangeness'. The modest differences in the transport model results -- on the other hand -- can be attributed to different implementations of string formation and fragmentation, that are not sufficiently controlled by experimental data for the 'elementary' reactions in vacuum.Comment: 46 pages, including 15 eps figures, to be published in Phys. Rev.

    Search for Λc+pK+π\Lambda_c^+ \to p K^+ \pi^- and Ds+K+K+πD_s^+ \to K^+ K^+ \pi^- Using Genetic Programming Event Selection

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    We apply a genetic programming technique to search for the double Cabibbo suppressed decays Λc+pK+π\Lambda_c^+ \to p K^+ \pi^- and Ds+K+K+πD_s^+ \to K^+ K^+ \pi^-. We normalize these decays to their Cabibbo favored partners and find BR(\text{BR}(\Lambda_c^+ \to p K^+ \pi^-)/BR()/\text{BR}(\Lambda_c^+ \to p K^- \pi^+)=(0.05±0.26±0.02)) = (0.05 \pm 0.26 \pm 0.02)% and BR(\text{BR}(D_s^+ \to K^+ K^+ \pi^-)/BR()/\text{BR}(D_s^+ \to K^+ K^- \pi^+)=(0.52±0.17±0.11)) = (0.52\pm 0.17\pm 0.11)% where the first errors are statistical and the second are systematic. Expressed as 90% confidence levels (CL), we find <0.46< 0.46 % and <0.78 < 0.78% respectively. This is the first successful use of genetic programming in a high energy physics data analysis.Comment: 10 page
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