79 research outputs found
Multicolored Temperley-Lieb lattice models. The ground state
Using inversion relation, we calculate the ground state energy for the
lattice integrable models, based on a recently obtained baxterization of non
trivial multicolored generalization of Temperley-Lieb algebras. The simplest
vertex and IRF models are analyzed and found to have a mass gap.Comment: 15 pages 2 figure
The Bethe ansatz as a matrix product ansatz
The Bethe ansatz in its several formulations is the common tool for the exact
solution of one dimensional quantum Hamiltonians. This ansatz asserts that the
several eigenfunctions of the Hamiltonians are given in terms of a sum of
permutations of plane waves. We present results that induce us to expect that,
alternatively, the eigenfunctions of all the exact integrable quantum chains
can also be expressed by a matrix product ansatz. In this ansatz the several
components of the eigenfunctions are obtained through the algebraic properties
of properly defined matrices. This ansatz allows an unified formulation of
several exact integrable Hamiltonians. We show how to formulate this ansatz for
a huge family of quantum chains like the anisotropic Heisenberg model,
Fateev-Zamolodchikov model, Izergin-Korepin model, model, Hubbard model,
etc.Comment: 4 pages and no figure
The short-term effect of swimming training load on shoulder rotational range of motion, shoulder joint position sense and pectoralis minor length
Background: Shoulder pain or injury is the most common issue facing elite competitive swimmers and the most frequent reason for missed or modified training. Literature suggests that highly repetitive upper limb loading leads to inappropriate adaptations within the shoulder complex. The most likely maladaptations to occur are variations in shoulder rotational range of motion, reduction in joint position sense and shortened pectoralis minor length. This has yet to have been confirmed in experimental studies. The aim of this study was to investigate the short-term effects of swimming training load upon internal and external rotation range of motion, joint position sense and pectoralis minor length.
Method: Sixteen elite swimmers training in the British Swimming World Class programme participated. Measures of internal and external range of motion, joint position sense error score and pectoralis minor length were taken before and after a typical 2h swimming session.
Results: Following swimming training shoulder external rotation range of motion and pectoralis minor length reduced significantly (-3.4°,p=<0.001 and -0.7cm, p=<0.001, respectively), joint position sense error increased significantly (+2.0° error angle, p=<0.001). Internal rotation range of motion demonstrated no significant change (-0.6, p=0.53).
Discussion: This study determined that elite level swimming training results in short-term maladaptive changes in shoulder performance that could potentially predispose them to injury
О сущности языковой компетенции
В статье даётся характеристика сущностных сторон языковой компетенции
как био и социального и интеллектуального феномена.У статті подається характеристика сутнісних сторін мовної компетенції як
біо та соціального та інтелектуального феномену.The characteristics of essential aspects of language competency as bio- and social
and intellectual phenomenon is given in the article
APOΕ4 Lowers Energy Expenditure in Females and Impairs Glucose Oxidation by Increasing Flux through Aerobic Glycolysis
BACKGROUND: Cerebral glucose hypometabolism is consistently observed in individuals with Alzheimer\u27s disease (AD), as well as in young cognitively normal carriers of the Ε4 allele of Apolipoprotein E (APOE), the strongest genetic predictor of late-onset AD. While this clinical feature has been described for over two decades, the mechanism underlying these changes in cerebral glucose metabolism remains a critical knowledge gap in the field.
METHODS: Here, we undertook a multi-omic approach by combining single-cell RNA sequencing (scRNAseq) and stable isotope resolved metabolomics (SIRM) to define a metabolic rewiring across astrocytes, brain tissue, mice, and human subjects expressing APOE4.
RESULTS: Single-cell analysis of brain tissue from mice expressing human APOE revealed E4-associated decreases in genes related to oxidative phosphorylation, particularly in astrocytes. This shift was confirmed on a metabolic level with isotopic tracing of 13C-glucose in E4 mice and astrocytes, which showed decreased pyruvate entry into the TCA cycle and increased lactate synthesis. Metabolic phenotyping of E4 astrocytes showed elevated glycolytic activity, decreased oxygen consumption, blunted oxidative flexibility, and a lower rate of glucose oxidation in the presence of lactate. Together, these cellular findings suggest an E4-associated increase in aerobic glycolysis (i.e. the Warburg effect). To test whether this phenomenon translated to APOE4 humans, we analyzed the plasma metabolome of young and middle-aged human participants with and without the Ε4 allele, and used indirect calorimetry to measure whole body oxygen consumption and energy expenditure. In line with data from E4-expressing female mice, a subgroup analysis revealed that young female E4 carriers showed a striking decrease in energy expenditure compared to non-carriers. This decrease in energy expenditure was primarily driven by a lower rate of oxygen consumption, and was exaggerated following a dietary glucose challenge. Further, the stunted oxygen consumption was accompanied by markedly increased lactate in the plasma of E4 carriers, and a pathway analysis of the plasma metabolome suggested an increase in aerobic glycolysis.
CONCLUSIONS: Together, these results suggest astrocyte, brain and system-level metabolic reprogramming in the presence of APOE4, a \u27Warburg like\u27 endophenotype that is observable in young females decades prior to clinically manifest AD
Thermal transport in one-dimensional spin gap systems
We study thermal transport in one dimensional spin systems both in the
presence and absence of impurities. In the absence of disorder, all these spin
systems display a temperature dependent Drude peak in the thermal conductivity.
In gapless systems, the low temperature Drude weight is proportional to
temperature and to the central charge which characterizes the conformal field
theory that describes the system at low energies. On the other hand, the low
temperature Drude weight of spin gap systems shows an activated behavior
modulated by a power law. For temperatures higher than the spin gap, one
recovers the linear T behavior akin to gapless systems. For temperatures larger
than the exchange coupling, the Drude weight decays as 1/T^2. We argue that
this behavior is a generic feature of quasi one dimensional spin gap systems
with a relativistic-like low energy dispersion. We also consider the effect of
a magnetic field on the Drude weight with emphasis on the
commensurate-incommensurate transition induced by it. We then study the effect
of nonmagnetic impurities on the thermal conductivity of the dimerized XY chain
and the spin-1/2 two leg ladder. Impurities destroy the Drude peak and the
thermal conductivity exhibits a purely activated behavior at low temperature,
with an activation gap renormalized by disorder. The relevance of these results
for experiments is briefly discussed.Comment: 13 pages, 6 eps figures, RevTeX
Applicant perspectives during selection
We provide a comprehensive but critical review of research on applicant reactions to selection procedures published since 2000 (n = 145), when the last major review article on applicant reactions appeared in the Journal of Management. We start by addressing the main criticisms levied against the field to determine whether applicant reactions matter to individuals and employers (“So what?”). This is followed by a consideration of “What’s new?” by conducting a comprehensive and detailed review of applicant reaction research centered upon four areas of growth: expansion of the theoretical lens, incorporation of new technology in the selection arena, internationalization of applicant reactions research, and emerging boundary conditions. Our final section focuses on “Where to next?” and offers an updated and integrated conceptual model of applicant reactions, four key challenges, and eight specific future research questions. Our conclusion is that the field demonstrates stronger research designs, with studies incorporating greater control, broader constructs, and multiple time points. There is also solid evidence that applicant reactions have significant and meaningful effects on attitudes, intentions, and behaviors. At the same time, we identify some remaining gaps in the literature and a number of critical questions that remain to be explored, particularly in light of technological and societal changes
Facial and dental alterations according to the breathing pattern
There is controversy in the literature about possible interaction of the respiratory mode with the facial and dental structures. OBJECTIVES: The aim of this study was to perform a longitudinal assessment of the changes in facial and dental structures in Angle's Class II, division 1 malocclusion individuals, divided according to the respiratory pattern (predominantly nasal or mouth), at two distinct moments of craniofacial development. MATERIAL AND METHODS: Pogonium and nose measurements were made on the lateral cephalometric tracings (LS'-Pog', LS'-B', B'-Pog', Pog'-PogTeg', Line NB, Pog-NB, N'-Prn, Prn-NPog, N-Prn-Sn, Prn-Sn-LS). Dental measurements were made on the plaster models (distances between the tips of the canine cusps and the tips of mesial cusps of the first molars) of 40 individuals aged 10 to 14 years (moment 1) and 13 to 16 years (moment 2), 23 being nose breathers (NB) and 17 being predominantly mouth breathers (MB). RESULTS: The Student's-t test and two-way ANOVA with repeated measures were applied to indicate differences between the mean values of these variables according to the moments and/or respiratory mode. CONCLUSIONS: There were alterations in the facial measurements, without interference of the breathing pattern. However, the breathing pattern infuenced dental alterations
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