958 research outputs found
Editorial: The War for Talent: Technologies and solutions toward competency and skills development and talent identification
This special issue is dedicated to advanced technological solutions and novel methodical approaches toward human capital management in terms of career development, assessment and recruitment as a driver for innovation and sustainable competitive advantage for academia and businesses in the changing conditions of the global employment market, and the War for Talent. Latest competitiveness-driven developments in productivity and services move forward human capital management and assessment technology and services alongside with talent identification as a driver for innovation and key source of maximizing the Return-On-Investment in people and technology in academia and businesses. Governments and businesses start thinking about competency and skills development as the critical issue for the workforce, and the workplaces. Against this background, a complex interrelationship arises between strategic management, human capital management, and the overall quality management in every educational and enterprise setting. In addition, identifying highly competent human capital develops into a challenging issue of the recruitment process.published_or_final_versio
Editorial: Smart cities of the future: Creating tomorrow’s education toward effective skills and career development today
published_or_final_versio
Development of Atmospheric Monitoring System at Akeno Observatory for the Telescope Array Project
We have developed an atmospheric monitoring system for the Telescope Array
experiment at Akeno Observatory. It consists of a Nd:YAG laser with an
alt-azimuth shooting system and a small light receiver. This system is
installed inside an air conditioned weather-proof dome. All parts, including
the dome, laser, shooter, receiver, and optical devices are fully controlled by
a personal computer utilizing the Linux operating system.
It is now operated as a back-scattering LIDAR System. For the Telescope Array
experiment, to estimate energy reliably and to obtain the correct shower
development profile, the light transmittance in the atmosphere needs to be
calibrated with high accuracy.
Based on observational results using this monitoring system, we consider this
LIDAR to be a very powerful technique for Telescope Array experiments. The
details of this system and its atmospheric monitoring technique will be
discussed.Comment: 24 pages, 13 figures(plus 3 gif files), Published in NIM-A Vol.488,
August 200
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Mechanism of Reovirus Double-Stranded Ribonucleic Acid Synthesis In Vivo and In Vitro
The complementary strands of reovirus double-stranded ribonucleic acid (ds RNA) are synthesized sequentially in vivo and in vitro. In both cases, preformed plus strands serve as templates for the synthesis of the complementary minus strands. The in vitro synthesis of dsRNA is catalyzed by a large particulate fraction from reovirus-infected cells. Treatment of this fraction with chymotrypsin or with detergents which solubilize cellular membranes does not alter its capacity to synthesize dsRNA. The enzyme or enzymes responsible for dsRNA synthesis remain sedimentable at 10,000 × g after these enzyme or detergent treatments, indicating their particulate nature. Pretreatment of this fraction with ribonuclease, however, abolishes its ability to catalyze dsRNA synthesis, emphasizing the single-stranded nature of the template and its location in a structure permeable to ribonuclease. In contrast, the newly formed dsRNA is resistant to ribonuclease digestion at low salt concentrations and hence is thought to reside within a ribonuclease-impermeable structure
Spirulina extract improves age-induced vascular dysfunction
Vascular dysfunction is considered a hallmark of ageing that has been associated with altered vasomotor responses, in which nitric oxide (NO) and reactive oxygen species participate. The consumption of Spirulina extracts, with antioxidant properties, increased recently. Objective: This study investigates the effect of Spirulina aqueous extract (SAE) on the vascular function of the aorta from aged rats. Materials and methods: Aortic segments from aged male Sprague-Dawley rats (20–22 months old) were exposed to SAE (0.1% w/v, for 3 h) to analyse: (i) the vasodilator response induced by acetylcholine (ACh), by the NO donor sodium nitroprusside (SNP), by the carbon monoxide releasing molecule (CORM) and by the KATP channel opener, cromakalim (CK); (ii) the vasoconstrictor response induced by KCl and noradrenaline (NA); (iii) the production of NO and superoxide anion, and (iv) the expression of the p-eNOS and HO-1 proteins. Results: Incubation with SAE increased the expression of p-eNOS (1.6-fold) and HO-1 (2.0-fold), enhanced NO release (1.4-fold in basal and 1.9-fold in ACh-stimulated conditions) while decreased the production of superoxide (0.7-fold). SAE also increased the sensitivity (measured as pEC50) to ACh (control: −7.06 ± 0.11; SAE: −8.16 ± 0.21), SNP (control: −7.96 ± 0.16; SAE: −9.11 ± 0.14) and CK (control: −7.05 ± 0.39; SAE: −8.29 ± 0.53), and potentiated the response to KCl (1.3-fold) and to NA (1.7-fold). Conclusion: The antioxidant properties of SAE improved the vasomotor responses of aorta from aged rats. These results may support the use of Spirulina as a protection against vascular dysfunctionThis study was supported by grants from Comunidad de Madrid(S2013/ABI-2783,‘INSPIRA1-CM’) and Fondo Europeo de Desarrollo Regional to C. O. and M. F., the Spanish Ministerio deCiencia e Innovaci on (CTQ2017-86170-R) to C. O. and by theFondo de Investigaciones Sanitarias del Instituto de Salud Carlos III(PI19/01282) to M.
Single- and two-particle observables in the Emery model: a dynamical mean-field perspective
We compare the dynamical mean-field descriptions of the single-band Hubbard
model and the three-band Emery model at the one- and two-particle level for
parameters relevant to high-Tc superconductors. We show that even within
dynamical mean-field theory, accounting solely for temporal fluctuations, the
intrinsic multi-orbital nature of the Emery model introduces effective
non-local correlations. These lead to a non-Curie-like temperature-dependence
of the magnetic susceptibility, also seen in nuclear magnetic resonance
experiments in the pseudogap regime by M. Avramovska, et al. [Journal of
Superconductivity and Novel Magnetism 33, 2621 (2020)]. We demonstrate the
agreement of our results with these experiments for a large range of dopings
and trace back the effective non-local correlations to an emerging
oxygen-copper singlet by analyzing a minimal finite-size cluster model. Despite
this correct description of the hallmark of the pseudogap at the two-particle
level, i.e., the drop in the Knight shift of nuclear magnetic resonance,
dynamical mean-field theory fails to properly describe the spectral properties
of the pseudogap.Comment: 7 pages, 7 figure
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