311 research outputs found

    Properties of low variability periods in financial time series

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    Properties of low-variability periods in the time series are analysed. The theoretical approach is used to show the relationship between the multi-scaling of low-variability periods and multi-affinity of the time series. It is shown that this technically simple method is capable of reveling more details about time-series than the traditional multi-affine analysis. We have applied this scaling analysis to financial time series: a number of daily currency and stock index time series. The results show a good scaling behaviour for different model parameters. The analysis of high-frequency USD-EUR exchange rate data confirmed the theoretical expectations.Comment: 14 pages, 5 figures, 3 tables, Submitted to Physica

    Econophysics studies in Estonia

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    A short review of the econophysics research done in Estonia, devoted to the 15th anniversary of the term "econophysics".Comment: Submitted to the special issue on "Econophysics" of the journal Science & Culture (http://www.scienceandculture-isna.org/journal.htm), a publication of the Indian Science News Association, established in 193

    Medical imaging

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    This infographic summarizes widely used medical imaging techniques

    Crystal structures and gas adsorption behavior of new lanthanide-benzene-1,4-dicarboxylate frameworks

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    Six new lanthanide metal organic complexes, i.e. [La2(NO2-BDC)3(H2O)4] (1) [Ln(L)0.5(NO2-BDC) (H2O)]·3H2O (Ln = Eu (2), Tb (3), Dy (4) and Ho (5); L = BDC2− or BDC2−/NO2-BDC2-) and [Tm(NO2-BDC)1.5(H2O)]·H2O (6), have been synthesized using mixed ligands of benzene-1,4-dicarboxylic acid (H2BDC) and the in situ generated 2-nitro-benzene-1,4-dicarboxylic acid (NO2-BDC2-). Single crystal structures and topologies of the complexes are presented based on the single crystal X-ray diffraction and spectroscopic data. Whilst the structures of 1 and 6 contain negligible voids, the frameworks of 2–5 are microporous in nature and stable upon the removal of all the water molecules from the structures and thermal treatment to over 400 °C. Based on the study of 2, significant adsorption capacities for carbon dioxide (95 cm3·g−1 or 4.2 mmol·g−1) and hydrogen (79 cm3·g−1 or 4 mmol·g−1), as well as the remarkable stability of the framework upon the sorption/desorption experiments are revealed

    Comparison of Swine Performance When Fed Diets Containing Corn Root Worm Protected Corn, Parental Line Corn, or Conventional Corn Grown During 2000 in Nebraska

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    This experiment was conducted to evaluate growth performance and carcass quality measurements in growing-finishing pigs fed diets containing either Corn Root Worm Protected Corn (CRW0586), the parental control corn (RX670), or two commercial sources of non-genetically modified corn (DK647 and RX740). The experiment used 72 barrows and 72 gilts with an average initial body weight of 50 lb. The pigs were allotted to a randomized complete block design with a 2 x 4 factorial arrangement of treatments (two sexes x four corn hybrids). The experiment continued until the average body weight was 260 lb, at which time all pigs were slaughtered. Real-time ultrasound measurements were taken on the final day of the experiment. Carcass quality measurements were made 24 hours postmortem. Corn hybrid did not affect average daily gain (ADG) or average daily feed intake (ADFI), but there was an effect of sex, with barrows having greater (P\u3c0.01) ADG and ADFI than gilts. Feed efficiency was not affected by the different corn hybrids, but gilts had improved (P\u3c0.01) feed efficiency compared to barrows during Finisher 1 (0.37 versus 0.35) and Finisher 2 (0.32 versus 0.30). Real-time ultrasound measurements were similar corns; however, a sex effect was detected for backfat (BF) depth, with gilts having less (P\u3c0.01) BJ than barrows (0.78 versus 0.98 in). There were no differences in carcass midline BF measurements among corns, but there was a significant difference between barrows and gilts, with gilts having less (P\u3c0.05) BF than barrows. Hot carcass weight was greater (P\u3c0.01) in barrows than gilts (210 versus 190 lb). Also, the percent carcass lean was greater (P\u3c0.01) in gilts than barrows (51.7 versus 49.5%). Longissimus muscle quality scores were similar among corns and between barrows and gilts. Analysis of longissimus muscle composition revealed no main effect of corn (P\u3e0.20) or sex (P\u3e0.30) for protein, fat, and water percentages. However, Corn Root Worm Protected Corn (73.1%) differed (P\u3c0.04) from parental control corn (73.6%) but not commercial corns (73.3 and 73.3%) in longissimus water content. In summary, there were no differences in growth performance or carcass measurements in growing-finishing pigs fed diets containing either Corn Root Worm Protected Corn, the parental control corn, or two commercial sources of non-genetically modified corn. Thus, the replacement of non-genetically modified corn. Thus, the replacement of non-transgenic corn with Corn Root Worm Protected Corn in growing-finishing diets will result in similar growth performance and(or) carcass measurements

    Extra-corporeal membrane oxygenation in the management of 2009 influenza A (H1N1) refractory respiratory failure.

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    Rapidly progressive acute respiratory failure attributed to 2009 H1N1 influenza A infection has been reported worldwide-3. Refractory hypoxaemia despite conventional mechanical ventilation and lung protective strategies has resulted in the use a combination of rescue therapies, such as conservative fluid management, prone positioning, inhaled nitric oxide, high frequency oscillatory ventilation and extracorporeal membrane oxygenation (ECMO)4. ECMO allows for pulmonary or cardiopulmonary support as an adjunct to respiratory and cardiac failure, minimising ventilator-associated lung injury (VALI). This permits treatment of the underlying disease process, while concurrently allowing for recovery of the acute lung injury. This case documents a previously healthy twenty-two year old Asian male patient with confirmed pandemic (H 1N1) 2009 influenza A who was successfully managed with ECMO in the setting of severe refractory hypoxaemia and progressive hypercapnia

    Cell surface IL-1α trafficking is specifically inhibited by interferon-γ, and associates with the membrane via IL-1R2 and GPI anchors.

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    IL-1 is a powerful cytokine that drives inflammation and modulates adaptive immunity. Both IL-1α and IL-1ÎČ are translated as proforms that require cleavage for full cytokine activity and release, while IL-1α is reported to occur as an alternative plasma membrane-associated form on many cell types. However, the existence of cell surface IL-1α (csIL-1α) is contested, how IL-1α tethers to the membrane is unknown, and signaling pathways controlling trafficking are not specified. Using a robust and fully validated system, we show that macrophages present bona fide csIL-1α after ligation of TLRs. Pro-IL-1α tethers to the plasma membrane in part through IL-1R2 or via association with a glycosylphosphatidylinositol-anchored protein, and can be cleaved, activated, and released by proteases. csIL-1α requires de novo protein synthesis and its trafficking to the plasma membrane is exquisitely sensitive to inhibition by IFN-Îł, independent of expression level. We also reveal how prior csIL-1α detection could occur through inadvertent cell permeabilisation, and that senescent cells do not drive the senescent-associated secretory phenotype via csIL-1α, but rather via soluble IL-1α. We believe these data are important for determining the local or systemic context in which IL-1α can contribute to disease and/or physiological processes.Work was funded by British Heart Foundation Grants FS/13/3/30038, FS/18/19/33371 and RG/16/8/32388 to MCHC, the BHF Cambridge CRE RE/13/6/30180, and the Cambridge NIHR Biomedical Research Centr

    Worldwide phylogeography and history of wheat genetic diversity

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    Since its domestication in the Fertile Crescent ~8000 to 10,000 years ago, wheat has undergone a complex history of spread, adaptation, and selection. To get better insights into the wheat phylogeography and genetic diversity, we describe allele distribution through time using a set of 4506 landraces and cultivars originating from 105 different countries genotyped with a high-density single-nucleotide polymorphism array. Although the genetic structure of landraces is collinear to ancient human migration roads, we observe a reshuffling through time, related to breeding programs, with the appearance of new alleles enriched with structural variations that may be the signature of introgressions from wild relatives after 1960

    Extraordinary Transmission and Enhanced Emission with Metallic Gratings Having Converging-Diverging Channels

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    Transmission metallic gratings having the shape of converging-diverging channel (CDC) give an extra degree of freedom to exhibit enhanced transmission resonances. By varying the gap size at the throat of CDC, the spectral locations of the transmission resonance bands can be shifted close to each other and have high transmittance in a very narrow energy band. Hence, the CDC shape metallic gratings can lead to almost perfect transmittance for any desired wavelength by carefully optimizing the metallic material, gap at the throat of CDC, and grating parameters. In addition, a cavity surrounded by the CDC shaped metallic grating and a one-dimensional (1D) photonic crystal (PhC) can lead to an enhanced emission with properties similar to a laser. The large coherence length of the emission is achieved by exploiting the coherence properties of the surface waves on the gratings and PhC. The new multilayer structure can attain the spectral and directional control of emission with only p-polarization. The resonance condition inside the cavity is extremely sensitive to the wavelength, which would then lead to high emission in a very narrow wavelength band. Such simple 1D multilayer structure should be easy to fabricate and have applications in photonic circuits, thermophotovoltaics, and potentially in energy efficient incandescent sources
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