Exile Vol. XIII No. 2

FICTION The Garden by Joyce Horvath 5-8 Early Morning Man by Harvey Spurlock 12-24 28 Nisan 1960 by Cem Kozlu 29-35 Letters to the Editor by Rick Brown 39-55 POETRY World II by Jeffrey R. Smith 1-4 It is not for no reason by Bonnie Bishop 9 I have often wondered by Mike Engle 10 Without opera glasses by Trudi Spaeth 10 Differentiations in August by Alan Pavlik 11 Gold by Nancy Scott 25 With images by Trudi Spaeth 25 Grandpa by Karen Cozart 26-27 Meditation on a Line by Sylvia Plath by Lauren Shakely 28 Bantling by Francie King 36 Haiku by Suzanne Husting 36 I saw you yesterday by Rick Tucker 37 My Eyes Would Escape 38 ART untitled by Nancy Eastlake 8 The Diary of a Madman by Clare Conrad 24 Trumpeter by Bill Henderson 38 Untitled by Nancy Eastlake Cover design: Kee McFarland With special thanks to Mrs. Louis Brakeman for her services

Genomewide Clonal Analysis of Lethal Mutations in the Drosophila melanogaster Eye: Comparison of the X Chromosome and Autosomes

Using a large consortium of undergraduate students in an organized program at the University of California, Los Angeles (UCLA), we have undertaken a functional genomic screen in the Drosophila eye. In addition to the educational value of discovery-based learning, this article presents the first comprehensive genomewide analysis of essential genes involved in eye development. The data reveal the surprising result that the X chromosome has almost twice the frequency of essential genes involved in eye development as that found on the autosomes