518 research outputs found

    Unions, Health and Safety Committees, and Workplace Accidents in the Korean Manufacturing Sector

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    AbstractBackgroundDespite the declining trend of workplace accidents in Republic of Korea, its level is still quite high compared with that in other developed countries. Factors that are responsible for high workplace accidents have not been well documented in Republic of Korea. The main purpose of this paper is to estimate the effects of unions and health and safety committees on workplace accidents in Korean manufacturing firms. We also allow for the interactions between unions and health and safety committees in the analysis. The results obtained in this paper will not only contribute to the literature in this field, but might also be useful for employers and worker representatives who are trying to find an effective way to reduce workplace accidents.MethodsThis paper utilizes the 2012 Occupational Safety and Health Trend Survey data, which is a unique data set providing information on workplace injuries and illness as well as other characteristics of participatory firms, representative of the manufacturing industry in Republic of Korea.ResultsIn estimating the effects of unions and health and safety committees, we build a negative binomial regression model in which the interactions between unions and health and safety committees are permissible in reducing workplace accidents.ConclusionHealth and safety committees were found to reduce the incidence of accidents whereas unionized establishments have higher incidence of accidents than nonunionized establishments. We also found that health and safety committees can more effectively reduce accidents in nonunionized establishments. By contrast, nonexclusive joint committees can more effectively reduce accidents in unionized establishments

    The Decline of the Self-Employment Rate in Australia

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    This paper using the Australian panel data(HILDA) investigates the declining trend of self-employment rate in Australia, a pattern observed in a number of other developed countries in the 2000s. We focus on the entry into and the exit from self-employment, treating males and females separately. Our results show that the self-employment rate has declined in Australia because older workers, especially older female workers, remained longer in paid-employment. This finding indicates that although the self-employment rate of older workers is higher than that of younger workers, the gap has decreased in recent years so that the average self-employment rate has declined. In addition, we provide some evidence that industry and institutional changes, such as reforms in tax and pension systems, may have contributed to an increase in the labour force participation of older females, which may explain why the decline of self-employment has been severe for this group

    An Analysis of Habitual Mode Use in the Years of Rising Oil Prices

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    The existence of state dependence derived from panel data has played a very important role in studying employment and labor policies. This study is about state dependence of the transportation sector using retrospective panel survey data. The Ministry of Land, Infrastructure and Transport of Korea has conducted the survey to monitor changes in vehicle ownership and usage nationwide and to prepare measures when oil prices tend to rise sharply. From this data, we identify the existence of state dependence on passenger cars, public transportation, and nonmotorized modes. To do this, we estimate and analyze the dynamic random effects probit model that explains the selection of each transportation mode after controlling for the unobserved individual heterogeneity. Our results indicate that despite the rise of oil prices, behavior of habitual use (i.e., state dependence) of transportation modes is found in all three modes. The amount of state dependence of nonmotorized modes was the largest, followed by passenger cars and public transportation. From the estimated models, important policy implications can be drawn from the fact that the presence of state dependence and the importance of early habit formation are important not only in nonmotorized modes but also in public transportation. In other words, if policy makers want to encourage people to use public transportation in a new city, it suggests that a sufficient and convenient public transportation network should be built before people move to the city. Once cities are built without sufficient public transportation networks and people have become accustomed to using private cars, then it will be more difficult to change their transportation modes, requiring much more social efforts and costs. Document type: Articl

    Heterogeneous amplification of ERBB2 in primary lesions is responsible for the discordant ERBB2 status of primary and metastatic lesions in gastric carcinoma

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    Aims: To determine the extent of HER2 homogeneity/heterogeneity in primary versus metastatic gastric carcinoma ( GC). Materials and results: The human epidermal growth factor receptor 2 ( HER2) status in primary and metastatic lesions was evaluated by immunohistochemistry ( IHC) and fluorescence in-situ hybridization ( FISH). Four separate cohorts consisting of primary GC alone or primary GC paired with metastatic lesions were examined. In the FISH analysis of 325 primary GCs, eight cases ( 2.5%) showed amplification with a heterogeneous pattern, whereas 27 cases ( 8.3%) showed amplification with a homogeneous pattern, and in this cohort the discordant: concordant FISH ratio based on examination of three different areas in each primary lesion was 0.30: 1. FISH testing using 250 paired primary and metastatic lesions revealed seven cases (2.8%) with discordant amplification. In metastatic disease positive conversion occurred in six cases (2.4%), whereas negative conversion happened in one case (0.4%). The discordant: concordant ratio of primary versus secondary lesions was 0.23: 1. When the seven discordant cases were re-evaluated using whole sections of primary GCs, six showed a heterogeneous pattern of amplification. Conclusions: These findings suggest that the discordant HER2 amplification observed in metastatic lesions is explained substantially by heterogeneity within primary tumours

    High-speed infrared phase modulators using short helical pitch ferroelectric liquid crystals

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    A fast phase modulator based on ferroelectric liquid crystal (FLC) is demonstrated and its performances characterized. For uniform alignment and pure phase modulation, we propose a new FLC device configuration using short helical pitch material and homeotropic alignment structure. This device is driven by periodic in-plane electrode stripes implemented on the surface of both cell substrates. As a result, we have obtained large phase modulation ( \u3e 2 pi at lambda=1.55 mu m) and fast response ( \u3c 200 mu sec)

    PDZ-based adaptor proteins in epithelial anion transport and VIP receptor regulation

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    Polarized protein deposition at the apical and basolateral membranes of epithelial cells is critical for the asymmetrical transport of ions and fluids across the epithelia. PDZ-based modular adaptor proteins are expressed in the junctional areas in epithelial cells and are generally part of a molecular scaffold that determines the localization and activity of ion channels, receptors, and other signaling molecules to their correct spatial arrangement for proper response to diverse stimuli. Hence, understanding the regulatory mechanisms of channels and receptors via PDZ-based adaptors will provide valuable insights into the physiology of epithelial cells as well as pathophysiology of many human diseases including cystic fibrosis

    Failure Modes of Silicon Powder Negative Electrode in Lithium Secondary Batteries

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    Si composite negative electrodes for lithium secondary batteries degrade in the dealloying period with an abrupt increase in internal resistance that is caused by a breakdown of conductive network made between Si and carbon particles. This results from a volume contraction of Si particles after expansion in the previous alloying process. Due to the large internal resistance, the dealloying reaction is not completed while Si remains as a lithiated state. The anodic performance is greatly improved either by applying a pressure on the cells or loading a larger amount of conductive carbon in the composite electrodes.This work was partially supported by KOSEF through Research Center for Energy Conversion and Storage, and by the financial support of Center for Nanostructured Materials Technology under 21st Century Frontier R&D Programs of the Ministry of Science and Technology, Korea. Financial support from LG Chem. Ltd. is also acknowledged

    Nanostructured, Self-Assembling Peptide K5 Blocks TNF-α and PGE2 Production by Suppression of the AP-1/p38 Pathway

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    Nanostructured, self-assembling peptides hold promise for a variety of regenerative medical applications such as 3D cell culture systems, accelerated wound healing, and nerve repair. The aim of this study was to determine whether the self-assembling peptide K5 can be applied as a carrier of anti-inflammatory drugs. First, we examined whether the K5 self-assembling peptide itself can modulate various cellular inflammatory responses. We found that peptide K5 significantly suppressed the release of tumor-necrosis-factor- (TNF-) α and prostaglandin E2 (PGE2) from RAW264.7 cells and peritoneal macrophages stimulated by lipopolysaccharide (LPS). Similarly, there was inhibition of cyclooxygenase- (COX-) 2 mRNA expression assessed by real-time PCR, indicating that the inhibition is at the transcriptional level. In agreement with this finding, peptide K5 suppressed the translocation of the transcription factors activator protein (AP-1) and c-Jun and inhibited upstream inflammatory effectors including mitogen activated protein kinase (MAPK), p38, and mitogen-activated protein kinase kinase 3/6 (MKK 3/6). Whether this peptide exerts its effects via a transmembrane or cytoplasmic receptor is not clear. However, our data strongly suggest that the nanostructured, self-assembling peptide K5 may possess significant anti-inflammatory activity via suppression of the p38/AP-1 pathway

    Overexpression of arabidopsis YUCCA6 in potato results in high-auxin developmental phenotypes and enhance

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    Indole-3-acetic acid (IAA), a major plant auxin, is produced in both tryptophan-dependent and tryptophanindependent pathways. A major pathway in Arabidopsis thaliana generates IAA in two reactions from tryptophan. Step one converts tryptophan to indole-3-pyruvic acid (IPA) by tryptophan aminotransferases followed by a rate-limiting step converting IPA to IAA catalyzed by YUCCA proteins. We identified eight putative StYUC (Solanum tuberosum YUCCA) genes whose deduced amino acid sequences share 50%-70% identity with those of Arabidopsis YUCCA proteins. All include canonical, conserved YUCCA sequences: FATGY motif, FMO signature sequence, and FAD-binding and NADPbinding sequences. In addition, five genes were found with ~50% amino acid sequence identity to Arabidopsis tryptophan aminotransferases. Transgenic potato (Solanum tuberosum cv. Jowon) constitutively overexpressing Arabidopsis AtYUC6 displayed high-auxin phenotypes such as narrow downward-curled leaves, increased height, erect stature, and longevity. Transgenic potato plants overexpressing AtYUC6 showed enhanced drought tolerance based on reduced water loss. The phenotype was correlated with reduced levels of reactive oxygen species in leaves. The results suggest a functional YUCCA pathway of auxin biosynthesis in potato that may be exploited to alter plant responses to the environment. © 2012 The Author
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