A Mini-survey of X-ray Point Sources in Starburst and Non-Starburst Galaxies

We present a comparison of X-ray point source luminosity functions of 3 starburst galaxies (the Antennae, M82, and NGC 253) and 4 non-starburst spiral galaxies (NGC 3184, NGC 1291, M83, and IC 5332). We find that the luminosity functions of the starbursts are flatter than those of the spiral galaxies; the starbursts have relatively more sources at high luminosities. This trend extends to early-type galaxies which have steeper luminosity functions than spirals. We show that the luminosity function slope is correlated with 60 micron luminosity, a measure of star formation. We suggest that the difference in luminosity functions is related to the age of the X-ray binary populations and present a simple model which highlights how the shape of the luminosity distribution is affected by the age of the underlying X-ray binary population.Comment: 8 pages, 4 figures. accepted for publication in Ap

High-Mass X-ray Binaries and the Spiral Structure of the Host Galaxy

We investigate the manifestation of the spiral structure in the distribution of high-mass X-ray binaries (HMXBs) over the host galaxy. We construct the simple kinematic model. It shows that the HMXBs should be displaced relative to the spiral structure observed in such traditional star formation rate indicators as the Halpha and FIR emissions because of their finite lifetimes. Using Chandra observations of M51, we have studied the distribution of X-ray sources relative to the spiral arms of this galaxy observed in Halpha. Based on K-band data and background source number counts, we have separated the contributions from high-mass and low-mass X-ray binaries and active galactic nuclei. In agreement with model predictions, the distribution of HMXBs is wider than that of bright HII regions concentrated in the region of ongoing star formation. However, the statistical significance of this result is low, as is the significance of the concentration of the total population of X-ray sources to the spiral arms. We also predict the distribution of HMXBs in our Galaxy in Galactic longitude. The distribution depends on the mean HMXB age and can differ significantly from the distributions of such young objects as ultracompact HII regions.Comment: 18 pages, 6 figures; Astronomy Letters, Vol. 33, No. 5, 2007, pp. 299-30

The Chandra Local Volume Survey: The X-ray Point Source Catalog of NGC 300

We present the source catalog of a new Chandra ACIS-I observation of NGC 300 obtained as part of the Chandra Local Volume Survey. Our 63 ks exposure covers ~88% of the D25 isophote (R~6.3 kpc) and yields a catalog of 95 X-ray point sources detected at high significance to a limiting unabsorbed 0.35-8 keV luminosity of ~10^36 erg s^-1. Sources were cross-correlated with a previous XMM-Newton catalog, and we find 75 "X-ray transient candidate" sources that were detected by one observatory, but not the other. We derive an X-ray scale length of 1.7+/-0.2 kpc and a recent star formation rate of 0.12 Msun yr^-1, in excellent agreement with optical observations. Deep, multi-color imaging from the Hubble Space Telescope, covering ~32% of our Chandra field, was used to search for optical counterparts to the X-ray sources, and we have developed a new source classification scheme to determine which sources are likely X-ray binaries, supernova remnants, and background AGN candidates. Finally, we present the X-ray luminosity functions (XLFs) at different X-ray energies, and we find the total NGC 300 X-ray point source population to be consistent with other late-type galaxies hosting young stellar populations (<50 Myr). We find XLF of sources associated with older stellar populations has a steeper slope than the XLF of X-ray sources coinciding with young stellar populations, consistent with theoretical predictions.Comment: 23 pages, 13 figures. Accepted to Ap

Precise sound characteristics drive plasticity in the primary auditory cortex with VNS-sound pairing

IntroductionRepeatedly pairing a tone with vagus nerve stimulation (VNS) alters frequency tuning across the auditory pathway. Pairing VNS with speech sounds selectively enhances the primary auditory cortex response to the paired sounds. It is not yet known how altering the speech sounds paired with VNS alters responses. In this study, we test the hypothesis that the sounds that are presented and paired with VNS will influence the neural plasticity observed following VNS-sound pairing.MethodsTo explore the relationship between acoustic experience and neural plasticity, responses were recorded from primary auditory cortex (A1) after VNS was repeatedly paired with the speech sounds ‘rad’ and ‘lad’ or paired with only the speech sound ‘rad’ while ‘lad’ was an unpaired background sound.ResultsPairing both sounds with VNS increased the response strength and neural discriminability of the paired sounds in the primary auditory cortex. Surprisingly, pairing only ‘rad’ with VNS did not alter A1 responses.DiscussionThese results suggest that the specific acoustic contrasts associated with VNS can powerfully shape neural activity in the auditory pathway. Methods to promote plasticity in the central auditory system represent a new therapeutic avenue to treat auditory processing disorders. Understanding how different sound contrasts and neural activity patterns shape plasticity could have important clinical implications

Chandra and Spitzer unveil heavily obscured quasars in the SWIRE/Chandra Survey

Using the large multi-wavelength data set in the chandra/SWIRE Survey (0.6 square degrees in the Lockman Hole), we show evidence for the existence of highly obscured (Compton-thick) AGN, estimate a lower limit to their surface density and characterize their multi-wavelength properties. Two independent selection methods based on the X-ray and infrared spectral properties are presented. The two selected samples contain 1) 5 X-ray sources with hard X-ray spectra and column densities > 10^24 cm-2, and 2) 120 infrared sources with red and AGN-dominated infrared spectral energy distributions (SEDs). We estimate a surface density of at least 25 Compton-thick AGN per square degree detected in the infrared in the chandra/SWIRE field of which ~40% show distinct AGN signatures in their optical/near-infrared SEDs, the remainings being dominated by the host-galaxy emission. Only ~33% of all Compton-thick AGN are detected in the X-rays at our depth (F(0.3-8 keV)>10^-15 erg/cm2/s. We report the discovery of two sources in our sample of Compton-thick AGN, SWIRE_J104409.95+585224.8 (z=2.54) and SWIRE_J104406.30+583954.1 (z=2.43), which are the most luminous Compton-thick AGN at high-z currently known. The properties of these two sources are discussed in detail with an analysis of their spectra, SEDs, luminosities and black-hole masses.Comment: ApJ accepted (to appear in May 2006 issue, vol. 642, of ApJ) Figures 2, 3, and 14 have been degraded due to space consideration

XMM-Newton observations of the interacting galaxy pairs NGC7771/0 and NGC2342/1

We present XMM-Newton X-ray observations of the interacting galaxy pairs NGC7771/7770 and NGC2342/2341. In NGC7771, for the first time we are able to resolve the X-ray emission into a bright central source (L(X)~10^41 erg/s), plus two (L(X)>10^40 erg/s) ultraluminous X-ray sources (ULXs) located either end of the bar. The soft emission of the central source is well-modelled by a two-temperature thermal plasma with kT=0.4/0.7 keV. The hard emission is modelled with a flat absorbed power-law (Gamma~1.7, NH~10^22 cm^2), and this together with a low-significance (1.7 sigma) ~300 eV equivalent width emission line at ~6 keV are the first indications that NGC7771 may host a low-luminosity AGN. For the bar ULXs, a power-law fit to X-1 is improved at the 2.5 sigma level with the addition of a thermal plasma component (kT~0.3 keV), while X-2 is improved only at the 1.3 sigma level with the addition of a disc blackbody component with T(in)~0.2 keV. Both sources are variable on short time-scales implying that their emission is dominated by single accreting X-ray binaries (XRBs). The three remaining galaxies, NGC7770, NGC2342 and NGC2341, have observed X-ray luminosities of 0.2, 1.8 & 0.9x10^41 erg/s respectively (0.3-10 keV). Their integrated spectra are also well-modelled by multi-temperature thermal plasma components with kT=0.2-0.7 keV, plus power-law continua with slopes of Gamma=1.8-2.3 that are likely to represent the integrated emission of populations of XRBs as observed in other nearby merger systems. A comparison with other isolated, interacting and merging systems shows that all four galaxies follow the established correlations for starburst galaxies between X-ray, far-infrared and radio luminosities, demonstrating that their X-ray outputs are dominated by their starburst components.Comment: 15 pages,7 figures. Accepted for publication in MNRA

Displacement of X-Ray Sources from Star Clusters in Starburst Galaxies

We examine the spatial offsets between X-ray point sources and star clusters in three starburst galaxies. We find that the X-ray sources are preferentially located near the star clusters. Because the star clusters are very good tracers of the star formation activity in the galaxies, this indicates that the X-ray sources are young objects associated with current star formation. We find significant displacements of the X-ray sources from the clusters. These displacements are likely due to motion of the X-ray sources and indicates that they are X-ray binaries. We find that brighter X-ray sources preferentially occur closer to clusters. The absence of very bright sources at large displacements from clusters may help constrain models of the sources.Comment: to appear in MNRAS letters, 5 pages, figure 1 is in color, astro-ph version is low resolutio

Physiological Properties of Cholinergic and Non-Cholinergic Magnocellular Neurons in Acute Slices from Adult Mouse Nucleus Basalis

The basal forebrain is a series of nuclei that provides cholinergic input to much of the forebrain. The most posterior of these nuclei, nucleus basalis, provides cholinergic drive to neocortex and is involved in arousal and attention. The physiological properties of neurons in anterior basal forebrain nuclei, including medial septum, the diagonal band of Broca and substantia innominata, have been described previously. In contrast the physiological properties of neurons in nucleus basalis, the most posterior nucleus of the basal forebrain, are unknown.Here we investigate the physiological properties of neurons in adult mouse nucleus basalis. We obtained cell-attached and whole-cell recordings from magnocellular neurons in slices from P42-54 mice and compared cholinergic and non-cholinergic neurons, distinguished retrospectively by anti-choline acetyltransferase immunocytochemistry. The majority (70-80%) of cholinergic and non-cholinergic neurons were silent at rest. Spontaneously active cholinergic and non-cholinergic neurons exhibited irregular spiking at 3 Hz and at 0.3 to 13.4 Hz, respectively. Cholinergic neurons had smaller, broader action potentials than non-cholinergic neurons (amplitudes 64+/-3.4 and 75+/-2 mV; half widths 0.52+/-0.04 and 0.33+/-0.02 ms). Cholinergic neurons displayed a more pronounced slow after-hyperpolarization than non-cholinergic neurons (13.3+/-2.2 and 3.6+/-0.5 mV) and were unable to spike at high frequencies during tonic current injection (maximum frequencies of approximately 20 Hz and >120 Hz).Our results indicate that neurons in nucleus basalis share similar physiological properties with neurons in anterior regions of the basal forebrain. Furthermore, cholinergic and non-cholinergic neurons in nucleus basalis can be distinguished by their responses to injected current. To our knowledge, this is the first description of the physiological properties of cholinergic and non-cholinergic neurons in the posterior aspects of the basal forebrain complex and the first study of basal forebrain neurons from the mouse

The Efficacy of Auditory Perceptual Training for Tinnitus: A Systematic Review

Auditory perceptual training affects neural plasticity and so represents a potential strategy for tinnitus management. We assessed the effects of auditory perceptual training on tinnitus perception and/or its intrusiveness via a systematic review of published literature. An electronic database search using the keywords ‘tinnitus and learning’ or ‘tinnitus and training’ was conducted, updated by a hand search. The ten studies identified were reviewed independently by two reviewers, data were extracted, study quality was assessed according to a number of specific criteria and the information was synthesised using a narrative approach. Nine out of the ten studies reported some significant change in either self-reported or psychoacoustic outcome measures after auditory training. However, all studies were quality rated as providing low or moderate levels of evidence for an effect. We identify a need for appropriately randomised and controlled studies that will generate high-quality unbiased and generalisable evidence to ascertain whether or not auditory perceptual training has a clinically relevant effect on tinnitus