1,621 research outputs found
Implementation of voyage data recording device using a digital forensics-based hash algorithm
Identifying the causes of marine accidents is difficult because of problems in scene preservation, reenactment, and procuring of witnesses. Thanks to new regulations, larger vessels are now required to carry voyage data recorders (VDRs) and automatic identification systems (AISs). However, the content of these devices, which is created, stored, and managed digitally, has security vulnerabilities such as the potential for data modification. Therefore, when managing digital records it is important to guarantee reliability. To this end, we suggest a digital forensics-based digital records migration method using a hash algorithm to guarantee the integrity and authenticity of digital records
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Development of an extension of GeoServer for handling 3D spatial data
Recently, several open source software tools such as CesiumJS and iTowns have been developed for dealing with 3-dimensional spatial data. These tools mainly focus on visualization of 3D spatial data based on WebGL. An open-sourced server capable of storing, sharing and querying 3D spatial data has not yet been developed. GeoServer, one of the representative open source spatial data servers, provides many powerful features. In particular, it supports connecting to and publishing spatial data from a variety of data sources. GeoServer also supports Web Feature Service (WFS), which is a standard protocol established by the Open Geospatial Consortium to request geospatial feature data. However, GeoServer provides functions only for two-dimensional geometry, so it provides few functions for handling 3D spatial data. Because JTS Topology Suite, which is an important component of GeoServer, does not support 3D spatial operations, it also does not support solid geometries. In this paper, we discuss extension modules of GeoServer that we have implemented to handle 3D spatial data. First, instead of JTS, our modules adopted a geometry model based on the ISO 19107 standard and support 3D spatial operations from the Simple Feature CGAL library. Based on this geometry model, we have implemented new internal data structures that represent spatial information from the Feature interface in GeoServer. Second, we also extended the DataStore module to handle and store 3D spatial information for several data sources such as GeoJSON, GML and PostGIS. Finally, we extended the WFS module to share 3D spatial data via GeoServer
Analysis of Change in the Wind Speed Ratio according to Apartment Layout and Solutions
Apartment complexes in various forms are built in downtown areas. The arrangement of an apartment complex has great influence on the wind flow inside it. There are issues of residents’ walking due to gust occurrence within apartment complexes, problems with pollutant emission due to airflow congestion, and heat island and cool island phenomena in apartment complexes. Currently, the forms of internal arrangements of apartment complexes are divided into the flat type and the tower type. In the present study, a wind tunnel experiment and computational fluid dynamics (CFD) simulation were performed with respect to internal wind flows in different apartment arrangement forms. Findings of the wind tunnel experiment showed that the internal form and arrangement of an apartment complex had significant influence on its internal airflow. The wind velocity of the buildings increased by 80% at maximum due to the proximity effects between the buildings. The CFD simulation for relaxing such wind flows indicated that the wind velocity reduced by 40% or more at maximum when the paths between the lateral sides of the buildings were extended
Incorporating Statistical Information of Lexical Dependency into a Rule-Based Parser
PACLIC 23 / City University of Hong Kong / 3-5 December 200
The voltage-gated potassium channel Shaker promotes sleep via thermosensitive GABA transmission
Genes and neural circuits coordinately regulate animal sleep. However, it remains elusive how these endogenous factors shape sleep upon environmental changes. Here, we demonstrate that Shaker (Sh)-expressing GABAergic neurons projecting onto dorsal fan-shaped body (dFSB) regulate temperature-adaptive sleep behaviors in Drosophila. Loss of Sh function suppressed sleep at low temperature whereas light and high temperature cooperatively gated Sh effects on sleep. Sh depletion in GABAergic neurons partially phenocopied Sh mutants. Furthermore, the ionotropic GABA receptor, Resistant to dieldrin (Rdl), in dFSB neurons acted downstream of Sh and antagonized its sleep-promoting effects. In fact, Rdl inhibited the intracellular cAMP signaling of constitutively active dopaminergic synapses onto dFSB at low temperature. High temperature silenced GABAergic synapses onto dFSB, thereby potentiating the wake-promoting dopamine transmission. We propose that temperature-dependent switching between these two synaptic transmission modalities may adaptively tune the neural property of dFSB neurons to temperature shifts and reorganize sleep architecture for animal fitness.
Ji-hyung Kim and Yoonhee Ki et al. show that low temperatures suppress sleep in Drosophila by increasing GABA transmission in Shaker-expressing GABAergic neurons projecting onto the dorsal fan-shaped body, while high temperatures potentiate dopamine-induced arousal by reducing GABA transmission. This study highlights a role for Shaker in sleep modulation via a temperature-dependent switch in GABA signaling
Toward a Standardized Strategy of Clinical Metabolomics for the Advancement of Precision Medicine
Despite the tremendous success, pitfalls have been observed in every step of a clinical metabolomics workflow, which impedes the internal validity of the study. Furthermore, the demand for logistics, instrumentations, and computational resources for metabolic phenotyping studies has far exceeded our expectations. In this conceptual review, we will cover inclusive barriers of a metabolomics-based clinical study and suggest potential solutions in the hope of enhancing study robustness, usability, and transferability. The importance of quality assurance and quality control procedures is discussed, followed by a practical rule containing five phases, including two additional "pre-pre-" and "post-post-" analytical steps. Besides, we will elucidate the potential involvement of machine learning and demonstrate that the need for automated data mining algorithms to improve the quality of future research is undeniable. Consequently, we propose a comprehensive metabolomics framework, along with an appropriate checklist refined from current guidelines and our previously published assessment, in the attempt to accurately translate achievements in metabolomics into clinical and epidemiological research. Furthermore, the integration of multifaceted multi-omics approaches with metabolomics as the pillar member is in urgent need. When combining with other social or nutritional factors, we can gather complete omics profiles for a particular disease. Our discussion reflects the current obstacles and potential solutions toward the progressing trend of utilizing metabolomics in clinical research to create the next-generation healthcare system.11Ysciescopu
Implantable cardioverter defibrillator as a treatment for massive left ventricular fibroma-induced ventricular arrhythmia in a child
Pediatric cardiac tumors are rare. Among these, cardiac fibroma is the second most common. Its clinical manifestations depend on size and location of the tumor and include arrhythmia or obstruction to blood flow. Symptomatic cardiac fibroma is generally treated with surgical resection or cardiac transplantation. We present the case of a 12-year-old boy with a lethal ventricular arrhythmia induced by a remnant tumor that was previously partially resected. An implantable cardioverter defibrillator was inserted as the arrhythmia was resistant to medical treatment. He was discharged in stable condition with an implantable cardioverter defibrillator generator and followed up in the outpatient clinic
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