404 research outputs found
Fatal Roseomonas gilardii bacteremia in a patient with refractory blast crisis of chronic myeloid leukemia
Modelling fine scale route choice of upstream migrating fish as they approach an instream structure
This study used pattern-oriented modelling (POM) to investigate the space use and behavioural response of upstream migrating European river lamprey (Lampetra fluviatilis) to the two-dimensional hydrodynamic conditions created by an instream structure (triangular profile gauging weir). Passive Integrated Transponder (PIT) and acoustic telemetry were used to map the spatial-temporal distribution patterns of lamprey as they migrated upstream. Acoustic Doppler velocimetry and computer modelling were used to quantify the hydrodynamic environment. In adherence with the POM methodology, multiple movement models, incorporating increasingly complex environmental feedback mechanisms and behavioural rules were created and systematically assessed to identify which factors might reproduce the observed patterns. The best model was a spatially explicit Eulerian-Lagrangian Individual Based Model (IBM) that included two simple behaviours: 1) tortuous non-directed swimming when in low flow velocity (< 0.1 m s−1) and 2) persistent directed (against the flow) swimming in moderate to high flow velocity (≥ 0.1 m s−1). The POM indicated that flow heterogeneity was an important influence of lamprey space use and that simple behavioural rules (i.e. two separate movement behaviours in response to flow velocity) were sufficient to reproduce the main movement pattern observed: avoidance of flow recirculating regions near the banks. The combination of field telemetry, hydrodynamic modelling and POM provided a useful framework for systematically identifying the key factors (hydrodynamic and behavioural) that governed the space use of the target species and would likely work well for investigating similar relationships in other aquatic species
Molecular dynamic simulation of a homogeneous bcc -> hcp transition
We have performed molecular dynamic simulations of a Martensitic bcc->hcp
transformation in a homogeneous system. The system evolves into three
Martensitic variants, sharing a common nearest neighbor vector along a bcc
direction, plus an fcc region. Nucleation occurs locally, followed by
subsequent growth. We monitor the time-dependent scattering S(q,t) during the
transformation, and find anomalous, Brillouin zone-dependent scattering similar
to that observed experimentally in a number of systems above the transformation
temperature. This scattering is shown to be related to the elastic strain
associated with the transformation, and is not directly related to the phonon
response.Comment: 11 pages plus 8 figures (GIF format); to appear in Phys. Rev.
Periodic Orbits and Escapes in Dynamical Systems
We study the periodic orbits and the escapes in two different dynamical
systems, namely (1) a classical system of two coupled oscillators, and (2) the
Manko-Novikov metric (1992) which is a perturbation of the Kerr metric (a
general relativistic system). We find their simple periodic orbits, their
characteristics and their stability. Then we find their ordered and chaotic
domains. As the energy goes beyond the escape energy, most chaotic orbits
escape. In the first case we consider escapes to infinity, while in the second
case we emphasize escapes to the central "bumpy" black hole. When the energy
reaches its escape value a particular family of periodic orbits reaches an
infinite period and then the family disappears (the orbit escapes). As this
family approaches termination it undergoes an infinity of equal period and
double period bifurcations at transitions from stability to instability and
vice versa. The bifurcating families continue to exist beyond the escape
energy. We study the forms of the phase space for various energies, and the
statistics of the chaotic and escaping orbits. The proportion of these orbits
increases abruptly as the energy goes beyond the escape energy.Comment: 28 pages, 23 figures, accepted in "Celestial Mechanics and Dynamical
Astronomy
Associations of lifetime concussion history and repetitive head impact exposure with resting-state functional connectivity in former collegiate American football players: An NCAA 15-year follow-up study
The objective of this study was to examine associations of lifetime concussion history (CHx) and an advanced metric of lifetime repetitive head impact exposure with resting-state functional connectivity (rsFC) across the whole-brain and among large-scale functional networks (Default Mode; Dorsal Attention; and Frontoparietal Control) in former collegiate football players. Individuals who completed at least one year of varsity collegiate football were eligible to participate in this observational cohort study (n = 48; aged 36-41 years; 79.2% white/ Caucasian; 12.5±4.4 years of football played; all men). Individuals were excluded if they reported history/suspicion of psychotic disorder with active symptoms, contraindications to participation in study procedures (e.g., MRI safety concern), or inability to travel. Each participant provided concussion and football playing histories. Self-reported concussion history was analyzed in two different ways based on prior research: dichotomous "High"(≥3 concussions; n = 28) versus "Low"(<3 concussions; n = 20); and four ordinal categories (0-1 concussion [n = 19]; 2-4 concussions [n = 8]; 5-7 concussions [n = 9]; and ≥8 concussions [n = 12]). The Head Impact Exposure Estimate (HIEE) was calculated from football playing history captured via structured interview. Resting-state fMRI and T1-weighted MRI were acquired and preprocessed using established pipelines. Next, rsFC was calculated using the Seitzman et al., (2020) 300-ROI functional atlas. Whole-brain, within-network, and between-network rsFC were calculated using all ROIs and network-specific ROIs, respectively. Effects of CHx and HIEE on rsFC values were examined using separate multivariable linear regression models, with a-priori α set to 0.05. We observed no statistically significant associations between rsFC outcomes and either CHx or HIEE (ps ≥ .12). Neither CHx nor HIEE were associated with neural signatures that have been observed in studies of typical and pathological aging. While CHx and repetitive head impacts have been associated with changes in brain health in older former athletes, our preliminary results suggest that associations with rsFC may not be present in early midlife former football players
Scale-free memory model for multiagent reinforcement learning. Mean field approximation and rock-paper-scissors dynamics
A continuous time model for multiagent systems governed by reinforcement
learning with scale-free memory is developed. The agents are assumed to act
independently of one another in optimizing their choice of possible actions via
trial-and-error search. To gain awareness about the action value the agents
accumulate in their memory the rewards obtained from taking a specific action
at each moment of time. The contribution of the rewards in the past to the
agent current perception of action value is described by an integral operator
with a power-law kernel. Finally a fractional differential equation governing
the system dynamics is obtained. The agents are considered to interact with one
another implicitly via the reward of one agent depending on the choice of the
other agents. The pairwise interaction model is adopted to describe this
effect. As a specific example of systems with non-transitive interactions, a
two agent and three agent systems of the rock-paper-scissors type are analyzed
in detail, including the stability analysis and numerical simulation.
Scale-free memory is demonstrated to cause complex dynamics of the systems at
hand. In particular, it is shown that there can be simultaneously two modes of
the system instability undergoing subcritical and supercritical bifurcation,
with the latter one exhibiting anomalous oscillations with the amplitude and
period growing with time. Besides, the instability onset via this supercritical
mode may be regarded as "altruism self-organization". For the three agent
system the instability dynamics is found to be rather irregular and can be
composed of alternate fragments of oscillations different in their properties.Comment: 17 pages, 7 figur
A pilot ASKAP survey of radio transient events in the region around the intermittent pulsar PSR J1107-5907
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