1,898 research outputs found
Equation of state of cosmic strings with fermionic current-carriers
The relevant characteristic features, including energy per unit length and
tension, of a cosmic string carrying massless fermionic currents in the
framework of the Witten model in the neutral limit are derived through
quantization of the spinor fields along the string. The construction of a Fock
space is performed by means of a separation between longitudinal modes and the
so-called transverse zero energy solutions of the Dirac equation in the vortex.
As a result, quantization leads to a set of naturally defined state parameters
which are the number densities of particles and anti-particles trapped in the
cosmic string. It is seen that the usual one-parameter formalism for describing
the macroscopic dynamics of current-carrying vortices is not sufficient in the
case of fermionic carriers.Comment: 30 pages, 15 figures, uses ReVTeX, equation of state corrected,
comments and references added. Accepted for publication in Phys. Rev.
Fermionic massive modes along cosmic strings
The influence on cosmic string dynamics of fermionic massive bound states
propagating in the vortex, and getting their mass only from coupling to the
string forming Higgs field, is studied. Such massive fermionic currents are
numerically found to exist for a wide range of model parameters and seen to
modify drastically the usual string dynamics coming from the zero mode currents
alone. In particular, by means of a quantization procedure, a new equation of
state describing cosmic strings with any kind of fermionic current, massive or
massless, is derived and found to involve, at least, one state parameter per
trapped fermion species. This equation of state exhibits transitions from
subsonic to supersonic regimes while the massive modes are filled.Comment: 27 pages, 15 figures, uses ReVTeX. Shortened version, accepted for
publication in Phys. Rev.
A Bisognano-Wichmann-like Theorem in a Certain Case of a Non Bifurcate Event Horizon related to an Extreme Reissner-Nordstr\"om Black Hole
Thermal Wightman functions of a massless scalar field are studied within the
framework of a ``near horizon'' static background model of an extremal R-N
black hole. This model is built up by using global Carter-like coordinates over
an infinite set of Bertotti-Robinson submanifolds glued together. The
analytical extendibility beyond the horizon is imposed as constraints on
(thermal) Wightman's functions defined on a Bertotti-Robinson sub manifold. It
turns out that only the Bertotti-Robinson vacuum state, i.e. , satisfies
the above requirement. Furthermore the extension of this state onto the whole
manifold is proved to coincide exactly with the vacuum state in the global
Carter-like coordinates. Hence a theorem similar to Bisognano-Wichmann theorem
for the Minkowski space-time in terms of Wightman functions holds with
vanishing ``Unruh-Rindler temperature''. Furtermore, the Carter-like vacuum
restricted to a Bertotti-Robinson region, resulting a pure state there, has
vanishing entropy despite of the presence of event horizons. Some comments on
the real extreme R-N black hole are given
A Hybrid Global Minimization Scheme for Accurate Source Localization in Sensor Networks
We consider the localization problem of multiple wideband sources in a
multi-path environment by coherently taking into account the attenuation
characteristics and the time delays in the reception of the signal. Our
proposed method leaves the space for unavailability of an accurate signal
attenuation model in the environment by considering the model as an unknown
function with reasonable prior assumptions about its functional space. Such
approach is capable of enhancing the localization performance compared to only
utilizing the signal attenuation information or the time delays. In this paper,
the localization problem is modeled as a cost function in terms of the source
locations, attenuation model parameters and the multi-path parameters. To
globally perform the minimization, we propose a hybrid algorithm combining the
differential evolution algorithm with the Levenberg-Marquardt algorithm.
Besides the proposed combination of optimization schemes, supporting the
technical details such as closed forms of cost function sensitivity matrices
are provided. Finally, the validity of the proposed method is examined in
several localization scenarios, taking into account the noise in the
environment, the multi-path phenomenon and considering the sensors not being
synchronized
Assessing the influence of pig slurry pH on the degradation of selected antibiotic compounds
Veterinary medicines are routinely used in animal husbandry and the environment may consequently be exposed to them via manure applications. This presents potential environmental and societal risks such as toxicological effects to aquatic/terrestrial organisms and the spread of antimicrobial resistance. Regulatory studies that assess the degradability of veterinary antibiotics during manure storage currently permit the use of just one manure per animal type although we speculate that heterogenic properties such as pH could be driving significant variability within degradation rates. To bridge this knowledge gap and assess degradation variability with pH, laboratory degradation studies were performed on a broad range of antibiotics (ceftiofur, florfenicol, oxytetracycline, sulfamethoxazole and tylosin) at three different environmentally relevant pH levels (5.5, 7, and 8.5). The effect of pig slurry pH on degradation rates was found to be significant and compound specific. Usually, acidic slurries were found to inhibit degradation when compared to neutral pH, for florfenicol, tylosin, and ceftiofur; the associated changes in DT50 (half-life) values were 2–209 h, 35.28–234 h, and 0.98–2.13 h, respectively. In some circumstances alkaline slurries were observed to enhance the degradation rate when compared to those for neutral pH, for tylosin, the respective changes in DT50 values were from 3.52 to 35.28 h. Comparatively, the degradation of sulfamethoxazole was enhanced by acidic conditions compared to neutral (DT50 20.6–31.6 h). Tentative identification of unknown transformation products (TPs) was achieved for sulfamethoxazole and florfenicol for the first time in pig slurries. These results reveal the importance of considering slurry pH when assessing the degradation of antibiotic compounds, which has implications for the acidification of manures and the environmental risk assessment for veterinary medicines. Environmental relevance and significance: Given the significant effect of pig slurry pH on degradation rates, manure degradation studies need to be harmonised and standardized, taking into account the influence of pH
Paranoia and post-traumatic stress disorder in the months after a physical assault: a longitudinal study examining shared and differential predictors.
Background: Being physically assaulted is known to increase the risk of the occurrence of post-traumatic stress disorder (PTSD) symptoms but it may also skew judgements about the intentions of other people. The objectives of the study were to assess paranoia and PTSD after an assault and to test whether theory-derived cognitive factors predicted the persistence of these problems. Method: At 4 weeks after hospital attendance due to an assault, 106 people were assessed on multiple symptom measures (including virtual reality) and cognitive factors from models of paranoia and PTSD. The symptom measures were repeated 3 and 6 months later. Results: Factor analysis indicated that paranoia and PTSD were distinct experiences, though positively correlated. At 4 weeks, 33% of participants met diagnostic criteria for PTSD, falling to 16% at follow-up. Of the group at the first assessment, 80% reported that since the assault they were excessively fearful of other people, which over time fell to 66%. Almost all the cognitive factors (including information-processing style during the trauma, mental defeat, qualities of unwanted memories, self-blame, negative thoughts about self, worry, safety behaviours, anomalous internal experiences and cognitive inflexibility) predicted later paranoia and PTSD, but there was little evidence of differential prediction. Conclusions: Paranoia after an assault may be common and distinguishable from PTSD but predicted by a strikingly similar range of factors
“Come and live with my feet and you’ll understand”–a qualitative study exploring the experiences of retail footwear in women with rheumatoid arthritis
Background: Foot pain and deformity are common in people with rheumatoid arthritis (RA). Previous research has identified that women with RA seek retail footwear to alleviate their foot problems. The specific footwear features that women with RA require, and what would help them to find shoes that meet these requirements, are unknown. This study aimed to determine the factors that influence the choice of appropriate retail footwear by women with RA. Method: An overarching qualitative approach was taken, using reflexive thematic analysis of conversational style interviews. The interviews explored experiences and use of retail footwear in 20 women with RA. The interviews were digitally recorded transcribed verbatim and analysed using a reflexive thematic framework. Results: Women with RA sought retail footwear which had adequate cushioning, width, a flexible sole, lightweight, were made from breathable materials and were easy to put on and take off. However, this choice was driven by the need for comfort, cost and usability, with aesthetics being less of a priority. Despite having opinions on what criteria they felt that they needed, these women did not feel empowered to make good choices about purchasing retail footwear for symptomatic relief. Furthermore, they did not receive the necessary support from podiatrists and shoe shop staff. Conclusion: Women with RA have clear ideas about what features a retail shoe should have to achieve comfort. There is a constant compromise between achieving comfort and their feelings about their appearance and how they feel others perceive them. Women with RA describe negative experiences with shoe shop assistants and podiatrists leading to poor footwear choices. Both retail staff and podiatrists need increased understanding about the particular problems that women with RA experience. Keywords: Footwear, Rheumatoid arthritis, Thematic analysi
Human umbilical cord perivascular cells improve human pancreatic islet transplant function by increasing vascularization
Islet transplantation is an efficacious therapy for type 1 diabetes; however, islets from multiple donor pancreata are required, and a gradual attrition in transplant function is seen. Here, we manufactured human umbilical cord perivascular mesenchymal stromal cells (HUCPVCs) to Good Manufacturing Practice (GMP) standards. HUCPVCs showed a stable phenotype while undergoing rapid ex vivo expansion at passage 2 (p2) to passage 4 (p4) and produced proregenerative factors, strongly suppressing T cell responses in the resting state and in response to inflammation. Transplanting an islet equivalent (IEQ):HUCPVC ratio of 1:30 under the kidney capsule in diabetic NSG mice demonstrated the fastest return to normoglycemia by 3 days after transplant: Superior glycemic control was seen at both early (2.7 weeks) and later stages (7, 12, and 16 weeks) versus ratios of 1:0, 1:10, and 1:50, respectively. Syngeneic islet transplantation in immunocompetent mice using the clinically relevant hepatic portal route with a marginal islet mass showed that mice transplanted with an IEQ:HUCPVC ratio of 1:150 had superior glycemic control versus ratios of 1:0, 1:90, and 1:210 up to 6 weeks after transplant. Immunodeficient mice transplanted with human islets (IEQ:HUCPVC ratio of 1:150) exhibited better glycemic control for 7 weeks after transplant versus islet transplant alone, and islets transplanted via the hepatic portal vein in an allogeneic mouse model using a curative islet mass demonstrated delayed rejection of islets when cotransplanted with HUCPVCs (IEQ:HUCPVC ratio of 1:150). The immunosuppressive and proregenerative properties of HUCPVCs demonstrated long-term positive effects on graft function in vivo, indicating that they may improve long-term human islet allotransplantation outcomes
Stationary Black Holes: Uniqueness and Beyond
The spectrum of known black-hole solutions to the stationary Einstein
equations has been steadily increasing, sometimes in unexpected ways. In
particular, it has turned out that not all black-hole-equilibrium
configurations are characterized by their mass, angular momentum and global
charges. Moreover, the high degree of symmetry displayed by vacuum and
electro-vacuum black-hole spacetimes ceases to exist in self-gravitating
non-linear field theories. This text aims to review some developments in the
subject and to discuss them in light of the uniqueness theorem for the
Einstein-Maxwell system.Comment: Major update of the original version by Markus Heusler from 1998.
Piotr T. Chru\'sciel and Jo\~ao Lopes Costa succeeded to this review's
authorship. Significantly restructured and updated all sections; changes are
too numerous to be usefully described here. The number of references
increased from 186 to 32
Can the Universe Create Itself?
The question of first-cause has troubled philosophers and cosmologists alike.
Now that it is apparent that our universe began in a Big Bang explosion, the
question of what happened before the Big Bang arises. Inflation seems like a
very promising answer, but as Borde and Vilenkin have shown, the inflationary
state preceding the Big Bang must have had a beginning also. Ultimately, the
difficult question seems to be how to make something out of nothing. This paper
explores the idea that this is the wrong question --- that that is not how the
Universe got here. Instead, we explore the idea of whether there is anything in
the laws of physics that would prevent the Universe from creating itself.
Because spacetimes can be curved and multiply connected, general relativity
allows for the possibility of closed timelike curves (CTCs). Thus, tracing
backwards in time through the original inflationary state we may eventually
encounter a region of CTCs giving no first-cause. This region of CTCs, may well
be over by now (being bounded toward the future by a Cauchy horizon). We
illustrate that such models --- with CTCs --- are not necessarily inconsistent
by demonstrating self-consistent vacuums for Misner space and a multiply
connected de Sitter space in which the renormalized energy-momentum tensor does
not diverge as one approaches the Cauchy horizon and solves Einstein's
equations. We show such a Universe can be classically stable and
self-consistent if and only if the potentials are retarded, giving a natural
explanation of the arrow of time. Some specific scenarios (out of many possible
ones) for this type of model are described. For example: an inflationary
universe gives rise to baby universes, one of which turns out to be itself.
Interestingly, the laws of physics may allow the Universe to be its own mother.Comment: 48 pages, 8 figure
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