12 research outputs found
Involvement of Fyn tyrosine kinase in actin stress fiber formation in fibroblasts
Get PDFAbstractLysophosphatidic acid (LPA) and sphingosylphosphorylcholine (SPC) activated Fyn tyrosine kinase and induced stress fiber formation, which was blocked by pharmacological inhibition of Fyn, gene silencing of Fyn, or dominant negative Fyn. Overexpressed constitutively active Fyn localized at both ends of F-actin bundles and triggered stress fiber formation, only the latter of which was abolished by Rho-kinase (ROCK) inhibition. SPC, but not LPA, induced filopodia-like protrusion formation, which was not mediated by Fyn and ROCK. Thus, Fyn appears to act downstream of LPA and SPC to specifically stimulate stress fiber formation mediated by ROCK in fibroblasts
13. Calcium inhibition of Physarum myosin in associated with its conformational change（第55回北関東医学会総会抄録）
No full text
13. Calcium inhibition of Physarum myosin in associated with its conformational change（第55回北関東医学会総会抄録）
No full text
Arginine kinase evolved twice: evidence that echinoderm arginine kinase originated from creatine kinase
No full textArginine kinase evolved twice: evidence that echinoderm arginine kinase originated from creatine kinase
No full textThe Involvement of Fyn Tyrosine Kinase in the Signal Transduction of Ca2+ sensitization of Vascular Smooth Muscle Contraction Mediated by Rho-kinase
No full text
