52 research outputs found

    Tuning the Band Gap Energy of Reduced Graphene Oxide Using Biopolymer Chitosan for High Power and Frequency Device Applications

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    There has been continued research to realize the potential of wide-bandgap (WBG) semiconductors for power switching applications since larger band gap allows higher power and temperature operation and the generation of more energetic (i.e. blue) photons. As compared to other semiconductor materials, reduced graphene oxide (rGO) has a low bandgap energy, which limits its application for high power semiconductors. Blending rGO with chitosan bio-polymer widens its bandgap, which can be tuned by controlling the amount of chitosan. In this study, the interplay between the resultant structure and opto-electronic properties of rGO obtained from coconut husks via thermal pyrolysis blended with chitosan from squid gladii have been systematically studied. We thus report that the optical band gap of rGO can be systematically controlled by careful addition of chitosan in their blend. This can give it a new application as high power semiconductors

    First recorded breeding of Clarke’s Weaver Ploceus golandi

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    The breeding site and nest of the Kenyan-endemic Clarke’s Weaver had remained a mystery for 100 years. The species was described in 1913 from the north Kenya Coast, but the first breeding colony was found in March 2013 in the northern section of the Dakatcha Woodlands, northwest of Malindi. An estimated 400–500 nests were concentrated in a small area of a tiny wetland. Adults were displaying and nest-building on 23 March, and when next visited on 7 April, adults were feeding young in the nest. Nests were coarsely woven with a low side entrance, placed in the tops of tall sedges, standing in water. Both males and females contributed to nest building and to feeding the young on insects, and breeding appeared to be closely synchronized, so that by 19 April the colony had been abandoned

    Quantifying long-term health and economic outcomes for survivors of group B Streptococcus invasive disease in infancy: protocol of a multi-country study in Argentina, India, Kenya, Mozambique and South Africa.

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    Sepsis and meningitis due to invasive group B Streptococcus (iGBS) disease during early infancy is a leading cause of child mortality. Recent systematic estimates of the worldwide burden of GBS suggested that there are 319,000 cases of infant iGBS disease each year, and an estimated 147,000 stillbirths and young-infant deaths, with the highest burden occurring in Sub-Saharan Africa.  The following priority data gaps were highlighted: (1) long-term outcome data after infant iGBS, including mild disability, to calculate quality-adjusted life years (QALYs) or disability-adjusted life years (DALYs) and (2) economic burden for iGBS survivors and their families. Geographic data gaps were also noted with few studies from low- and middle- income countries (LMIC), where the GBS burden is estimated to be the highest. In this paper we present the protocol for a multi-country matched cohort study designed to estimate the risk of long-term neurodevelopmental impairment (NDI), socioemotional behaviors, and economic outcomes for children who survive invasive GBS disease in Argentina, India, Kenya, Mozambique, and South Africa. Children will be identified from health demographic surveillance systems, hospital records, and among participants of previous epidemiological studies. The children will be aged between 18 months to 17 years. A tablet-based custom-designed application will be used to capture data from direct assessment of the child and interviews with the main caregiver. In addition, a parallel sub-study will prospectively measure the acute costs of hospitalization due to neonatal sepsis or meningitis, irrespective of underlying etiology. In summary, these data are necessary to characterize the consequences of iGBS disease and enable the advancement of effective strategies for survivors to reach their developmental and economic potential. In particular, our study will inform the development of a full public health value proposition on maternal GBS immunization that is being coordinated by the World Health Organization

    SARS-CoV-2 seroprevalence in pregnant women in Kilifi, Kenya from March 2020 to March 2022

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    BackgroundSeroprevalence studies are an alternative approach to estimating the extent of transmission of SARS-CoV-2 and the evolution of the pandemic in different geographical settings. We aimed to determine the SARS-CoV-2 seroprevalence from March 2020 to March 2022 in a rural and urban setting in Kilifi County, Kenya.MethodsWe obtained representative random samples of stored serum from a pregnancy cohort study for the period March 2020 to March 2022 and tested for antibodies against the spike protein using a qualitative SARS-CoV-2 ELISA kit (Wantai, total antibodies). All positive samples were retested for anti-SARS-CoV-2 anti-nucleocapsid antibodies (Euroimmun, ELISA kits, NCP, qualitative, IgG) and anti-spike protein antibodies (Euroimmun, ELISA kits, QuantiVac; quantitative, IgG).ResultsA total of 2,495 (of 4,703 available) samples were tested. There was an overall trend of increasing seropositivity from a low of 0% [95% CI 0–0.06] in March 2020 to a high of 89.4% [95% CI 83.36–93.82] in Feb 2022. Of the Wantai test-positive samples, 59.7% [95% CI 57.06–62.34] tested positive by the Euroimmun anti-SARS-CoV-2 NCP test and 37.4% [95% CI 34.83–40.04] tested positive by the Euroimmun anti-SARS-CoV-2 QuantiVac test. No differences were observed between the urban and rural hospital but villages adjacent to the major highway traversing the study area had a higher seroprevalence.ConclusionAnti-SARS-CoV-2 seroprevalence rose rapidly, with most of the population exposed to SARS-CoV-2 within 23 months of the first cases. The high cumulative seroprevalence suggests greater population exposure to SARS-CoV-2 than that reported from surveillance data
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