Height loss in adulthood is associated with health outcomes in later life in men and women enrolled in the 1946 UK Birth Cohort (NSHD)

Objective: To investigate the relationship between height in childhood and relative height loss in adulthood, and to examine the association between height loss and health at age 69. Design: Cohort study. Setting: Data from one of the oldest ongoing cohort studies, the National Survey of Health and Development (NSHD, 1946 UK birth cohort) Participants: 2,119 study participants who completed the nurse home visit during the 24th and most recent available follow-up examination at age 69. Main outcome measures: Linear regression models to estimate the association between meas-ured height in childhood years relative height loss between ages 36 and 69. Logistic regression models using generalized additive models to estimate the probability of worse health at age 69 (chronic disease score, general health status, osteoarthritis, and pain while walking) in associa-tion with height loss. Results: Between the ages of 36 and 69, men lost an average of 2.03 cm and women 2.44 cm. Women lost significantly more height than men (p<0.001). The taller the participants were at a young age, the more height they lost in adulthood. There was a significant association between height loss in adulthood on the one hand and general health, chronic disease score (in men), osteoarthritis (in men), and walking pain at age 69. These findings largely persisted after adjust-ing the models for overweight, sociodemographic information, and lifestyle factors earlier in life. Conclusions: Height loss seems to mirror deteriorating health as people age. Height measurement and assessment of height loss should be part of regular examinations after the age of 40 to monitor general health status, especially in the case of severe height loss

An Unwanted but Long-Known Company: Post-Viral Symptoms in the Context of Past Pandemics in Switzerland (and Beyond)

Objectives: Some people do not fully recover from an acute viral infection and experience persistent symptoms or incomplete recovery for months or even years. This is not unique to the SARS-CoV-2 virus and history shows that post-viral conditions like post COVID-19 condition, also referred to as Long Covid, are not new. In particular, during and after pandemics caused by respiratory viruses in which large parts of the population were infected or exposed, professional and public attention was increased, not least because of the large number of people affected. Methods: Given the current relevance of the topic, this article aims to narratively review and summarize the literature on post-viral symptoms during past pandemics and to supplement and illustrate it with Swiss examples from the pandemics of 1890, 1918–1920 and later. Results: Post-viral diseases were an increasingly emphasised health topic during and after past pandemics triggered by respiratory infections over the last 150 years. Conclusion: In the next pandemic, it should not be surprising that post-viral conditions will again play a role, and pandemic plans should reflect this