Radio Broadcasting Experience and Development Prospects (European Scientific Dialogue)

The paper presents an analysis of various opinions concerning radio-industry development issues, given new IT processes implemented in mass media. The authors study the technological evolution of radio broadcasting in terms of analyzing its main development stages. They provide an assessment of listeners’ high confidence in radio broadcasts as compared to other mass media sources. Focus is placed on promoting sonic brands in the sphere of media-communication. The researchers also pay special attention to podcasting as a new way to listen to audio-content. The advantages and possible consequences of podcasting influence on radio-industry are assessed. The research is based on the expert discussion on radio broadcasting issues which took place at “Radiodays Europe 2019”

Convergência organizacional como a tendência do desenvolvimento moderno de mídia de mass

Convergence is а key problem of modern mass media development. It mediates changes in content policy, media products distribution, and economic activity of media. Organizational convergence is one of the types of this phenomenon. It acts to make structural changes both in the media market and within a certain media. The purpose of such changes is to expand the influence of the media on the media market, to reduce the cost of its maintenance and development, and to expand social audience by transmedia distributing of the content. The article is devoted to the problems of understanding the phenomenon of organizational convergence as one of the types of convergence in the modern media environment. It also studies the main ways of building new forms of media organization.La convergencia es un problema clave del desarrollo moderno de los medios de comunicación. Medita los cambios en la política de contenido, la distribución de productos de medios y la actividad económica de los medios. La convergencia organizacional es uno de los tipos de este fenómeno. Actúa para realizar cambios estructurales tanto en el mercado de medios como dentro de ciertos medios. El objetivo de tales cambios es ampliar la influencia de los medios en el mercado de los medios, reducir el costo de su mantenimiento y desarrollo, y expandir la audiencia social mediante la distribución transmedia del contenido. El artículo está dedicado a los problemas de comprensión del fenómeno de la convergencia organizacional como uno de los tipos de convergencia en el entorno de los medios modernos. También estudia las principales maneras de construir nuevas formas de organización de los medios.A convergência é um problema fundamental no desenvolvimento moderno da mídia. Considere as mudanças na política de conteúdo, a distribuição de produtos de mídia e a atividade econômica da mídia. A convergência organizacional é um dos tipos desse fenômeno. Atua para fazer mudanças estruturais tanto no mercado de mídia quanto em certas mídias. O objetivo de tais mudanças é expandir a influência da mídia no mercado de mídia, reduzir o custo de manutenção e desenvolvimento e expandir o público social através da distribuição transmídia de conteúdo. O artigo é dedicado aos problemas de entender o fenômeno da convergência organizacional como um dos tipos de convergência no ambiente da mídia moderna. Também estuda as principais formas de construir novas formas de organização de mídia

Omecamtiv mecarbil in chronic heart failure with reduced ejection fraction, GALACTIC‐HF: baseline characteristics and comparison with contemporary clinical trials

Aims: The safety and efficacy of the novel selective cardiac myosin activator, omecamtiv mecarbil, in patients with heart failure with reduced ejection fraction (HFrEF) is tested in the Global Approach to Lowering Adverse Cardiac outcomes Through Improving Contractility in Heart Failure (GALACTIC‐HF) trial. Here we describe the baseline characteristics of participants in GALACTIC‐HF and how these compare with other contemporary trials. Methods and Results: Adults with established HFrEF, New York Heart Association functional class (NYHA) ≥ II, EF ≤35%, elevated natriuretic peptides and either current hospitalization for HF or history of hospitalization/ emergency department visit for HF within a year were randomized to either placebo or omecamtiv mecarbil (pharmacokinetic‐guided dosing: 25, 37.5 or 50 mg bid). 8256 patients [male (79%), non‐white (22%), mean age 65 years] were enrolled with a mean EF 27%, ischemic etiology in 54%, NYHA II 53% and III/IV 47%, and median NT‐proBNP 1971 pg/mL. HF therapies at baseline were among the most effectively employed in contemporary HF trials. GALACTIC‐HF randomized patients representative of recent HF registries and trials with substantial numbers of patients also having characteristics understudied in previous trials including more from North America (n = 1386), enrolled as inpatients (n = 2084), systolic blood pressure < 100 mmHg (n = 1127), estimated glomerular filtration rate < 30 mL/min/1.73 m2 (n = 528), and treated with sacubitril‐valsartan at baseline (n = 1594). Conclusions: GALACTIC‐HF enrolled a well‐treated, high‐risk population from both inpatient and outpatient settings, which will provide a definitive evaluation of the efficacy and safety of this novel therapy, as well as informing its potential future implementation

Impact strength of underground cement materials

The article presents the results of a study of impact strength of underground cement materials with different water content activated by mixing water with the addition of high range plasticizers, biocidal agents, pigments, ground quartz, silica fume and fine aggregate. Samples for testing are formed in plates of size 150×100×10 mm. Testing was conducted at impact drop-weight method ASTM D7136. The maximum contact force, contact duration and magnitude of the pulse of the drummer were considered as the test parameters. The good results of the studied parameters showed highly filled plasticized compositions of the new generation. The use of iron oxide with yellow and green glauconitic pigments allows obtaining good results. Activation of the mixing water led to a rise in the maximum contact force in the case of the processing mode of E+М (3–3) while reducing the duration of the contact and the magnitude of the impulse. During the test of the biocidal composites with different biocidal preparations, it was established that the best indicators of the impact strength correspond to materials with the addition of «Teflex Antiplesen»

Educational Potential of New Media

Digitalization of the mass media, which has radically changed the information environment, creates new opportunities for self-education and upgrowth of the audience. The paper defines the communicative and cultural status of new media, characterizes the socio-cultural and technological aspects of their dynamics; substantiates the necessity of elaborating mechanisms for systematization of heterogeneous information flows and elaborating criteria for their evaluation in the era of globalization of the media sphere, what implies a qualitatively different level of media competence of the audience, provided with such factors as media education, media coverage, media criticism. The definition of concepts "media competence", "media enlightenment", "media education", "media criticism" is given and their functional areas are delineated. Social networks are considered as an important tool for media enlightenment which provides significant opportunities for promoting cultural achievements in the new media environment

Activated Carbon for Drug Delivery from Composite Biomaterials: The Effect of Grinding on Sirolimus Binding and Release

Activated carbon (AC) could be potentially useful as a drug carrier in fiber polymer scaffolds destined for prolonged drug delivery. To be introduced, AC must be ground into smaller-sized particles to be introduced in scaffolds, as most biocompatible scaffolds consist of fibers with a diameter of less than 1 µm. In this study, the adsorption of sirolimus (SRL) from phosphate-buffered saline (PBS) solution and blood plasma (BP) onto AC of AX-21 type, as well as the release of SRL from AC depending on its fragmentation, were studied. Two-stage grinding of the AC, first with a ball mill, and then with a bead mill, was performed. Grinding with a bead mill was performed either in water or in polyvinylpyrrolidone to prevent aggregation of AC particles. Dynamic light scattering and scanning electron microscopy (SEM) demonstrated that the size of the particles obtained after grinding with a ball mill was 100–10,000 nm, and after grinding with a bead mill, 100–300 nm. Adsorption in PBS was significantly higher than in BP for all fractions, and depended on SRL concentration. The fraction obtained after grinding with a ball mill showed maximal SRL adsorption, both in PBS and BP, and slow SRL release, in comparison with other fractions. The 100–300 nm AC fractions were able to adsorb and completely release SRL into BP, in contrast to other fractions, which strongly bound a significant amount of SRL. The data obtained are to be used for controlled SRL delivery, and thus in the modification of drug delivery in biological media