Hazard ratios and 95% confidence intervals for the incidence of total strokes (N = 6,157), non-fatal strokes (N = 6,048), and fatal strokes (N = 5,758) according to self-reported sleep duration (hours per 24 hours), men aged 25 to 74 years.

<p>Abbreviation: HR: hazard ratio, CI: confidence interval, N: Size of the underlying study population with regard to the particular stroke outcome, h: hour.</p><p>Model 1: crude model (unadjusted).</p><p>Model 2: adjusted for age (continuous) and survey (1, 2, 3, 4).</p><p>Model 3: “Socio-demographic and lifestyle model” was, in addition to model 2, further adjusted for education (low, high), physical activity (>2 h/week, 1 h/week (regular), 1 h/week (irregular), no sport), alcohol consumption (men: 0–39 g/day, ≥40 g/day; women: 0–19 g/day, ≥20 g/day), current smoking activity (yes, no).</p><p>Model 4: The full model (“health status model”) was, in addition to model 3, adjusted for BMI (continuous), hypertension (yes, no), diabetes (yes, no), dyslipidemia (yes, no).</p><p>¹ Number of incident stroke cases.</p><p>Hazard ratios and 95% confidence intervals for the incidence of total strokes (N = 6,157), non-fatal strokes (N = 6,048), and fatal strokes (N = 5,758) according to self-reported sleep duration (hours per 24 hours), men aged 25 to 74 years.</p

Prevalence (%) and mean (±standard deviation) of baseline population characteristics by sex and incident total strokes, men and women aged 25 to 74 years (N = 15,746).

<p>¹ Variable was available for 15,742 individuals.</p><p>² Variable was available for 15,732 individuals.</p><p>³ Variable was available for 10,945 individuals. Median and interquartile range.</p><p>⁴ Variable was available for 12,131 individuals.</p><p>Prevalence (%) and mean (±standard deviation) of baseline population characteristics by sex and incident total strokes, men and women aged 25 to 74 years (N = 15,746).</p

Hazard ratios and 95% confidence intervals for the incidence of total strokes (N = 7,911), non-fatal strokes (N = 7,796), and fatal strokes (N = 7,456) according to self-reported symptoms of insomnia, men aged 25 to 74 years.

<p>Abbreviation: HR: hazard ratio, CI: confidence interval, N: Size of the underlying study population with regard to the particular stroke outcome.</p><p>Model 1: crude model (unadjusted).</p><p>Model 2: adjusted for age (continuous) and survey (1, 2, 3, 4).</p><p>Model 3: “Socio-demographic and lifestyle model” was, in addition to model 2, further adjusted for education (low, high), physical activity (>2 h/week, 1 h/week (regular), 1 h/week (irregular), no sport), alcohol consumption (men: 0–39 g/day, ≥40 g/day; women: 0–19 g/day, ≥20 g/day), current smoking activity (yes, no).</p><p>Model 4: The full model (“health status model”) was, in addition to model 3, adjusted for BMI (continuous), hypertension (yes, no), diabetes (yes, no), dyslipidemia (yes, no).</p><p>¹ Number of incident stroke cases.</p><p>Hazard ratios and 95% confidence intervals for the incidence of total strokes (N = 7,911), non-fatal strokes (N = 7,796), and fatal strokes (N = 7,456) according to self-reported symptoms of insomnia, men aged 25 to 74 years.</p

Assessment of diseases in the KORA-Age Study.

<p>*none of the participants reported antiretroviral therapy in the medication history.</p

Number and percent of persons who could be assigned to the multimorbidity patterns.

<p>Results of Chi²-test for sex and age-group differences.</p

Prevalences of the 13 chronic conditions.

<p>Prevalences of the 13 chronic conditions.</p

Association of PTSD with telomere length estimated by linear regression.

<p><i>1) Model 1 was adjusted for age, sex and BMI.</i></p><p><i>2) Model 2 was adjusted for age, sex and additionally for smoking status, alcohol consumption, physical inactivity, actual hypertension, TC/HDL and history of chronic diseases.</i></p><p><i>R²: 0.187 (model 1), 0.188 (model 2).</i></p

Mean telomere length of study participants, stratified by PTSD status and adjusted for age, sex, BMI, smoking status, alcohol consumption, physical inactivity, actual hypertension, TC/HDL-C and history of chronic diseases.

<p><i>Vertical reference line denotes mean TL for no PTSD</i>.</p

Distribution of characteristics of the study population (n = 3,000) by PTSD status.

<p><i>Distributions are presented as means ± standard deviation for continuous, p values from χ² test or F test for association with PTSD,</i></p>*<p><i>only n = 2,528.</i></p

Adjusted Odds Ratios (95% CI) for the Association Between Job Strain and Diabetes (N = 44,818 in All Models), the IPD-Work Consortium, 1984–2003.

<p>Adjusted Odds Ratios (95% CI) for the Association Between Job Strain and Diabetes (N  =  44,818 in All Models), the IPD-Work Consortium, 1984–2003.</p