2,107 research outputs found

    First Report of Fusarium equiseti as the Causal Agent of Seed Rot of Matthiola longipetala in Serbia

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    Matthiola longipetala (Vent) DC, commonly known as "night-scented stock" or "evening stock" is the most widely cultivated species of the genus Matthiola in the family Brassicaceae. It is a common garden flower, available in a variety of colours, many of which are heavily scented and also used in floristry. An elevated incidence of Fusarium was observed during a routine quality control seed assay of M. longipetala obtained from a private production facility in Đurđevo, Serbia in 2018. To our knowledge, this is the first report of F. equiseti as a causal agent of seed rot on M. longipetala in Serbia

    Clip-level feature aggregation : a key factor for video-based person re-identification

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    In the task of video-based person re-identification, features of persons in the query and gallery sets are compared to search the best match. Generally, most existing methods aggregate the frame-level features together using a temporal method to generate the clip-level fea- tures, instead of the sequence-level representations. In this paper, we propose a new method that aggregates the clip-level features to obtain the sequence-level representations of persons, which consists of two parts, i.e., Average Aggregation Strategy (AAS) and Raw Feature Utilization (RFU). AAS makes use of all frames in a video sequence to generate a better representation of a person, while RFU investigates how batch normalization operation influences feature representations in person re- identification. The experimental results demonstrate that our method can boost the performance of existing models for better accuracy. In particular, we achieve 87.7% rank-1 and 82.3% mAP on MARS dataset without any post-processing procedure, which outperforms the existing state-of-the-art

    Multi-agent Poli-RRT* Optimal constrained RRT-based planning for multiple vehicles with feedback linearisable dynamics

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    Planning a trajectory that is optimal according to some performance criterion, collision-free, and feasible with respect to dynamic and actuation constraints is a key functionality of an autonomous vehicle. Poli-RRT* is a sample-based planning algorithm that serves this purpose for a single vehicle with feedback linearisable dynamics. This paper extends Poli-RRT* to a multi-agent cooperative setting where multiple vehicles share the same environment and need to avoid each other besides some static obstacles

    Different paths to the modern state in Europe: the interaction between domestic political economy and interstate competition

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    Theoretical work on state formation and capacity has focused mostly on early modern Europe and on the experience of western European states during this period. While a number of European states monopolized domestic tax collection and achieved gains in state capacity during the early modern era, for others revenues stagnated or even declined, and these variations motivated alternative hypotheses for determinants of fiscal and state capacity. In this study we test the basic hypotheses in the existing literature making use of the large date set we have compiled for all of the leading states across the continent. We find strong empirical support for two prevailing threads in the literature, arguing respectively that interstate wars and changes in economic structure towards an urbanized economy had positive fiscal impact. Regarding the main point of contention in the theoretical literature, whether it was representative or authoritarian political regimes that facilitated the gains in fiscal capacity, we do not find conclusive evidence that one performed better than the other. Instead, the empirical evidence we have gathered lends supports to the hypothesis that when under pressure of war, the fiscal performance of representative regimes was better in the more urbanized-commercial economies and the fiscal performance of authoritarian regimes was better in rural-agrarian economie

    Synthesis and biologic properties of hydrophilic sapphyrins, a new class of tumor-selective inhibitors of gene expression

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    BACKGROUND: Sapphyrin analogues and related porphyrin-like species have attracted attention as anticancer agents due to their selective localization in various cancers, including hematologic malignancies, relative to surrounding tissues. Sapphyrins are electron affinic compounds that generate high yields of singlet oxygen formation. Although initially explored in the context of photodynamic therapy, sapphyrins have intrinsic anticancer activity that is independent of their photosensitizing properties. However, the mechanisms for their anticancer activity have not been fully elucidated. RESULTS: We have prepared a series of hydrophilic sapphyrins and evaluated their effect on proliferation, uptake, and cell death in adherent human lung (A549) and prostate (PC3) cancer cell lines and in an A549 xenograft tumor model. PCI-2050, the sapphyrin derivative with the highest in vitro growth inhibitory activity, significantly lowered 5-bromo-2'-deoxyuridine incorporation in S-phase A549 cells by 60% within eight hours and increased levels of reactive oxygen species within four hours. The growth inhibition pattern of PCI-2050 in the National Cancer Institute 60 cell line screen correlated most closely using the COMPARE algorithm with known transcriptional or translational inhibitors. Gene expression analyses conducted on A549 plateau phase cultures treated with PCI-2050 uncovered wide-spread decreases in mRNA levels, which especially affected short-lived transcripts. Intriguingly, PCI-2050 increased the levels of transcripts involved in RNA processing and trafficking, transcriptional regulation, and chromatin remodeling. We propose that these changes reflect the activation of cellular processes aimed at countering the observed wide-spread reductions in transcript levels. In our A549 xenograft model, the two lead compounds, PCI-2050 and PCI-2022, showed similar tumor distributions despite differences in plasma and kidney level profiles. This provides a possible explanation for the better tolerance of PCI-2022 relative to PCI-2050. CONCLUSION: Hydrophilic sapphyrins were found to display promise as novel agents that localize to tumors, generate oxidative stress, and inhibit gene expression

    Combined search for the quarks of a sequential fourth generation

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    Results are presented from a search for a fourth generation of quarks produced singly or in pairs in a data set corresponding to an integrated luminosity of 5 inverse femtobarns recorded by the CMS experiment at the LHC in 2011. A novel strategy has been developed for a combined search for quarks of the up and down type in decay channels with at least one isolated muon or electron. Limits on the mass of the fourth-generation quarks and the relevant Cabibbo-Kobayashi-Maskawa matrix elements are derived in the context of a simple extension of the standard model with a sequential fourth generation of fermions. The existence of mass-degenerate fourth-generation quarks with masses below 685 GeV is excluded at 95% confidence level for minimal off-diagonal mixing between the third- and the fourth-generation quarks. With a mass difference of 25 GeV between the quark masses, the obtained limit on the masses of the fourth-generation quarks shifts by about +/- 20 GeV. These results significantly reduce the allowed parameter space for a fourth generation of fermions.Comment: Replaced with published version. Added journal reference and DO

    Measurement of the t t-bar production cross section in the dilepton channel in pp collisions at sqrt(s) = 7 TeV

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    The t t-bar production cross section (sigma[t t-bar]) is measured in proton-proton collisions at sqrt(s) = 7 TeV in data collected by the CMS experiment, corresponding to an integrated luminosity of 2.3 inverse femtobarns. The measurement is performed in events with two leptons (electrons or muons) in the final state, at least two jets identified as jets originating from b quarks, and the presence of an imbalance in transverse momentum. The measured value of sigma[t t-bar] for a top-quark mass of 172.5 GeV is 161.9 +/- 2.5 (stat.) +5.1/-5.0 (syst.) +/- 3.6(lumi.) pb, consistent with the prediction of the standard model.Comment: Replaced with published version. Included journal reference and DO

    Search for supersymmetry in events with b-quark jets and missing transverse energy in pp collisions at 7 TeV

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    Results are presented from a search for physics beyond the standard model based on events with large missing transverse energy, at least three jets, and at least one, two, or three b-quark jets. The study is performed using a sample of proton-proton collision data collected at sqrt(s) = 7 TeV with the CMS detector at the LHC in 2011. The integrated luminosity of the sample is 4.98 inverse femtobarns. The observed number of events is found to be consistent with the standard model expectation, which is evaluated using control samples in the data. The results are used to constrain cross sections for the production of supersymmetric particles decaying to b-quark-enriched final states in the context of simplified model spectra.Comment: Submitted to Physical Review
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