16 research outputs found

    BNT162b2 or CoronaVac Vaccinations Are Associated With a Lower Risk of Myocardial Infarction and Stroke After SARSā€CoVā€2 Infection Among Patients With Cardiovascular Disease

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    Background: COVIDā€19 vaccines have demonstrated effectiveness against SARSā€CoVā€2 infection, hospitalization, and mortality. The association between vaccination and risk of cardiovascular complications shortly after SARSā€CoVā€2 infection among patients with cardiovascular disease remains unknown. Methods and Results: A caseā€“control study was conducted with cases defined as patients who had myocardial infarction or stroke within 28ā€‰days after SARSā€CoVā€2 infection between January 1, 2022 and August 15, 2022. Controls were defined as all other patients who attended any health services and were not cases. Individuals without history of cardiovascular disease were excluded. Each case was randomly matched with 10 controls according to sex, age, Charlson comorbidity index, and date of hospital admission. Adjusted odds ratio with 95% CI was estimated using conditional logistic regression. We identified 808 cases matched with 7771 controls among all patients with cardiovascular disease. Results showed that vaccination with BNT162b2 or CoronaVac was associated with a lower risk of myocardial infarction or stroke after SARSā€CoVā€2 infection with a doseā€“response relationship. For BNT162b2, risk decreased from 0.49 (95% CI, 0.29ā€“0.84) to 0.30 (95% CI, 0.20ā€“0.44) and 0.17 (95% CI, 0.08ā€“0.34) from 1 to 3 doses, respectively. Similar trends were observed for CoronaVac, with risk decreased from 0.69 (95% CI, 0.57ā€“0.85) to 0.42 (95% CI, 0.34ā€“0.52) and 0.32 (95% CI, 0.21ā€“0.49) from 1 to 3 doses, respectively. Conclusions: Vaccination with BNT162b2 or CoronaVac is associated with a lower risk of myocardial infarction or stroke after SARSā€CoVā€2 infection among patients with cardiovascular disease

    Synthesis and photosensitizing properties of conjugated polymers that contain chlorotricarbonyl bis(phenylimino)acenaphthene rhenium(I) complexes

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    A series of poly(p-phenylenevinylene)s that contain chlorotricarbonyl bis(phenylimino)acenaphthene rhenium(I) complexes on the conjugated main chain was synthesized by the palladium catalyzed coupling reaction. The chloride ligand could be displaced by the iodide generated in situ during the polymerization reaction. The ligand displacement reaction was studied by synthesizing two model compounds, whose structures were confirmed by X-ray crystallography. The metal content in the polymers could be adjusted by varying the monomer feed ratio in the polymerization. The photosensitizing properties of these metal-containing polymers were studied, and it was found that the photocurrent response was dependent on the metal content in the polymers. Multilayered photovoltaic devices were fabricated, and their properties were studied by irradiation with simulated solar light. Typical power conversion efficiencies for these devices were measured to be 0.06%, with a fill factor of approximately 0.2. Ā© 2004 Elsevier B.V. All rights reserved.link_to_subscribed_fulltex
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