A Study on Manjal Kamalai

SUMMARY: In India there are many existing predisposing factors which produce jaundice. Economically poor social status and literacy are mainly responsible for the poor knowledge about Jaundice. Manjal Kamalai, a pitha type of disorder with considerable involvement of liver and gall bladder and wide constitutional feature was taken for this study. Improper Hygienic measures like unpreserved water supply and drainage system in most places and improperly preserved food items, comtaminated needles and blood products favour the spread and development of this disease. Accurate labeling of Jaundice in every case is essential to study the nature and to take preventive measures. Among 50 patients admitted, 42 patients had given a history of contact with infected persons, 8 patients had taking excessive spicy, sour and pungent taste items. So Increased Pitha Kutram and them affected normal function of liver and it produced jaundice. The clinical feature of the manjal kamalai resembles the clinical entity of infective hepatitis, discussed in varios literature collected in siddha and modern side dealing with the disease. 50 cases were admitted for study in the In-patient department. Amoung the patients 20 were Male and 30 were female. The diagnosis of this disease were made on the basis of eight types of clinical investigation, and mukkuttram mentional in siddha literature with concurrent practical application of modern clinical and laboratorical approach. The important observation during this study has been shown that no patients were developed or reported any features of further complications like coma, Intestinal hemorrhage etc. The occurrence of this disease was marked in kaar, Koothir and mudhuvenil kalam. The common belief of the publc is that the siddha medicines and diet prescribes are more effective in the treatment of manjal kamalai is once again established by the clinical study. The cost of the medicine used in the treatment of jaundice is very low, that is very cheap when compared with the cost of other medicine s used in the treatment of jaundice. The adverse side effect are nil in the treatment of jaundice by the Siddha Medicine

Classification of EEG signals on standing, walking and running dataset using LSTM-RNN

Undoubtedly one of the most important strands of the brain-computer interface (BCI) method is an alternate communication method via brain signals. BCI converts electroencephalogram (EEG) signals from a perception of activity in the brain into user action utilising software and hardware. BCI has piqued the interest of researchers in a wide range of disciplines, such as cognitive science, deep learning, pattern matching, drug treatment medicine, etc. Patients suffering from neuro and cognitive disorders can be assisted through BCI, potentially enabling communication via gestures or just mental imagination. In this paper, a novel combination of Discrete Wavelet Transform (DWT) for extracting the best features and Long Short-Term Memory (LSTM) based Recurrent Neural Network (RNN) is adopted for classifying the EEG signals acquired during standing, walking and running on a treadmill. The dataset used is freely downloaded from Open Science Framework repository. The proposed DWT-LSTMRNN method delivers 96.7% accuracy while classifying four different signals, and thus has the potential to be investigated further on BCI competition datasets that will pave way for a real-time application

Study of TORCH infections and its impact on newborn babies and infants: a retrospective study in a tertiary care hospital in Visakhapatnam, Andhra Pradesh, India

Background: TORCH is an acronym for Toxoplasma, others (syphilis), Rubella, Cytomegalovirus and Herpes simplex virus. These are important causes of morbidity and mortality in new-borns, infants and children. Early diagnosis and treatment are essential to reduce the morbidity and mortality.Methods: It was a cross sectional record based retrospective record-based study conducted in King George Hospital, Andhra Medical College, Visakhapatnam, Andhra Pradesh. Samples from clinically suspected cases (newborns and infants) for possible TORCH infections were tested in virology laboratory from January to November 2019 and the samples were collected and tested by EUROIMMUN kit for the respective IgM antibodies and analyzed. Clinical details of newborns and infants were gathered from the patients through telephonic communication.Results: Total number of patients tested were 104 in which 54 (52%) showed positivity in which 36 were positive for CMV, 25 for HSV2, 23 for Rubella, 12 for Toxoplasma and 11 for Varicella zoster infection. Out of 52 positive cases 20.4% were alive and normal, 20% were alive but severely affected, mortality was 16.7%. Out of 16.7% mortalities 22% of deaths were due to nephrotic syndrome. Clinical manifestations include hepato-splenomegaly in 33.3% cases, fever in 30%, low birth weight in 25%, heart disease in 13.7%, microcephaly in 13.7%.Conclusions: Our study showed hepatomegaly, fever and low birth weight as common clinical manifestations. Fever and nephrotic syndrome were typically associated with CMV positive cases. Out of 52 % positively tested cases CMV was very common infection followed by HSV2, Rubella and Toxoplasmosis

FisHook -- An Optimized Approach to Marine Specie Classification using MobileNetV2

Marine ecosystems are vital for the planet's health, but human activities such as climate change, pollution, and overfishing pose a constant threat to marine species. Accurate classification and monitoring of these species can aid in understanding their distribution, population dynamics, and the impact of human activities on them. However, classifying marine species can be challenging due to their vast diversity and the complex underwater environment. With advancements in computer performance and GPU-based computing, deep-learning algorithms can now efficiently classify marine species, making it easier to monitor and manage marine ecosystems. In this paper, we propose an optimization to the MobileNetV2 model to achieve a 99.83% average validation accuracy by highlighting specific guidelines for creating a dataset and augmenting marine species images. This transfer learning algorithm can be deployed successfully on a mobile application for on-site classification at fisheries

GC-MS analysis of yellow pigmented Macrococcus equipercicus isolated from alfalfa rhizosphere soil fields of Coimbatore

The rhizosphere of plant possesses important microflora, which secretes wide chemical compounds including secondary metabolites necessary for plant growth and development. The microbial flora of alfalfa plant rhizosphere soil region was explored for functional activity and we found upto ten different pigmented colonies. Due to good functional diversity, this yellow pigmented colony was taken for further studies. Thus, the culture was molecularly characterized and identified for potent bioactive components responsible for antimicrobial activity. The selected culture mass was cultured and secondary metabolites were produced and extracted using ethyl acetate and subjected to GC-MS analysis. The antimicrobial study revealed selective activity against Streptococcus pneumonia, and Proteus sp with zone of inhibition to be 18 and 20 mm respectively.  Molecular identification of the isolate by 16S rRNA sequencing showed the isolate as Macrococcus equipercicus with 100 % similarity. Based on GC-MS analysis report 25bioactive compounds were identified and 13-docosenamide, hexadecanoic acid esters and quercetin were found in ethyl acetate extract. Conclusion: Thus the yellow pigmented gram positive cocci M.equipercicus isolated from Medicago sativa possessed wide antibacterial activity due to presence of quercetin. Through the studies, we were able to identify potent antibacterial compound producing bacteria from M. sativa plant rhizosphere soil

Dialysis-associated peritonitis in children

Peritonitis remains a frequent complication of peritoneal dialysis in children and is the most common reason for technique failure. The microbiology is characterized by a predominance of Gram-positive organisms, with fungi responsible for less than 5% of episodes. Data collected by the International Pediatric Peritonitis Registry have revealed a worldwide variation in the bacterial etiology of peritonitis, as well as in the rate of culture-negative peritonitis. Risk factors for infection include young age, the absence of prophylactic antibiotics at catheter placement, spiking of dialysis bags, and the presence of a catheter exit-site or tunnel infection. Clinical symptoms at presentation are somewhat organism specific and can be objectively assessed with a Disease Severity Score. Whereas recommendations for empiric antibiotic therapy in children have been published by the International Society of Peritoneal Dialysis, epidemiologic data and antibiotic susceptibility data suggest that it may be desirable to take the patient- and center-specific history of microorganisms and their sensitivity patterns into account when prescribing initial therapy. The vast majority of patients are treated successfully and continue peritoneal dialysis, with the poorest outcome noted in patients with peritonitis secondary to Gram-negative organisms or fungi and in those with a relapsing infection

Evaluation of spent coffee obtained from the most common coffeemakers as a source of hydrophilic bioactive compounds

The main hydrophilic antioxidant compounds (3-, 4-, and 5-monocaffeoylquinic and 3,4-, 3,5-, and 4,5-dicaffeoylquinic acids, caffeine, and browned compounds, including melanoidins) and the antioxidant capacity (Folin-Ciocalteu, ABTS, DPPH, Fremy's salt, and TEMPO) were evaluated in Arabica and Robusta spent coffee obtained from the preparation of coffee brews with the most common coffeemakers (filter, espresso, plunger, and mocha). All spent coffee grounds, with the exception of those from the mocha coffeemaker, had relevant amounts of total caffeoylquinic acids (6.22-13.24 mg/g of spent coffee), mainly dicaffeoylquinic acids (3.31-5.79 mg/g of spent coffee), which were 4-7-fold higher than in their respective coffee brews. Caffeine ranged from 3.59 to 8.09 mg/g of spent coffee. The antioxidant capacities of the aqueous spent coffee extracts were 46.0-102.3% (filter), 59.2-85.6% (espresso), and <42% (plunger) in comparison to their respective coffee brews. This study obtained spent coffee extracts with antioxidant properties that can be used as a good source of hydrophilic bioactive compounds

Wpływ zachowań obywatelskich w miejscu pracy na osiągnięcie konkurencyjności organizacyjnej

This study aims to estimate the level of corporate citizenship behavior impact on organizational competitiveness. Further, the study investigates how organizational competitiveness leads to better organizational performance. This study was conducted using a descriptive research approach. The novelty of this research is that Organisational Citizenship Behaviour is studied with Organisational Performance alone which is found in the literature review. This research aims at finding the mediating effect of Organisational Competitiveness. The researcher herein used a simple random sampling technique. From the analysis, it was found that the variables considered under organizational citizenship behaviour, organizational performance and organizational competitiveness are reliable and can be considered for futuristic studies. From the analysis, it was found that Organizational Citizenship Behaviour (OCB) has a significant impact on Organizational Competitiveness. Furthermore, it was shown that organizational citizenship conduct significantly impacts organizational performance, with organizational competitiveness acting as the mediating variable. In addition to that, organizational citizenship conduct has been found to have a direct impact on the organization's performance.Niniejsze badanie ma na celu oszacowanie wpływu zachowań obywatelskich korporacji na konkurencyjność organizacji. Ponadto w badaniu zbadano, w jaki sposób konkurencyjność organizacyjna prowadzi do lepszych wyników organizacyjnych. Niniejsze badanie zostało przeprowadzone przy użyciu opisowego podejścia badawczego. Nowatorstwo tego badania polega na tym, że zachowanie obywatelskie organizacji jest badane wyłącznie na podstawie wyników organizacji, które można znaleźć w przeglądzie literatury. Badanie to ma na celu znalezienie pośredniczącego efektu konkurencyjności organizacji. Badacz zastosował tutaj prostą technikę losowego próbkowania. Na podstawie analizy stwierdzono, że zmienne brane pod uwagę w ramach zachowań obywatelskich organizacji, wydajności organizacyjnej i konkurencyjności organizacyjnej są wiarygodne i można je uwzględnić w badaniach futurystycznych. Na podstawie analizy stwierdzono, że zachowanie obywatelstwa organizacyjnego (OCB) ma istotny wpływ na konkurencyjność organizacji. Ponadto wykazano, że postawa obywatelska organizacji istotnie wpływa na wyniki organizacyjne, a konkurencyjność organizacyjna jest zmienną pośredniczącą. Ponadto stwierdzono, że postępowanie obywatelskie w organizacji ma bezpośredni wpływ na wyniki organizacji