780 research outputs found
Structural, elastic, and electronic properties of newly discovered Li2PtSi3 superconductor: Effect of transition metals
First-principles calculations within the density functional theory (DFT) with
GGA-PBE exchange-correlation scheme have been employed to predict the
structural, the elastic and the electronic properties of newly discovered
lithium silicide superconductor, Li2PtSi3, for the first time. All the
theoretical results are compared with those calculated recently for
isostructural Li2IrSi3. The present study sheds light on the effect of
replacement of transition metal element Ir with Pt on different mechanical,
electronic, and superconducting properties. The effect of spin-orbit coupling
on electronic band structure was found to be insignificant for Li2PtSi3. The
difference in superconducting transition temperatures of Li2PtSi3 and Li2IrSi3
arises primarily due to the difference in electronic energy density of states
at the Fermi level. Somewhat reduced Debye temperature in Li2PtSi3 plays a
minor role. We have discussed the implications of the theoretical results in
details in this study.Comment: Submitted for publicatio
Sparse multitask regression for identifying common mechanism of response to therapeutic targets
Motivation: Molecular association of phenotypic responses is an important step in hypothesis generation and for initiating design of new experiments. Current practices for associating gene expression data with multidimensional phenotypic data are typically (i) performed one-to-one, i.e. each gene is examined independently with a phenotypic index and (ii) tested with one stress condition at a time, i.e. different perturbations are analyzed separately. As a result, the complex coordination among the genes responsible for a phenotypic profile is potentially lost. More importantly, univariate analysis can potentially hide new insights into common mechanism of response
Estimation of the Optimal Statistical Quality Control Sampling Time Intervals Using a Residual Risk Measure
Background: An open problem in clinical chemistry is the estimation of the optimal sampling time intervals for the application of statistical quality control (QC) procedures that are based on the measurement of control materials. This is a probabilistic risk assessment problem that requires reliability analysis of the analytical system, and the estimation of the risk caused by the measurement error. Methodology/Principal Findings: Assuming that the states of the analytical system are the reliability state, the maintenance state, the critical-failure modes and their combinations, we can define risk functions based on the mean time of the states, their measurement error and the medically acceptable measurement error. Consequently, a residual risk measure rr can be defined for each sampling time interval. The rr depends on the state probability vectors of the analytical system, the state transition probability matrices before and after each application of the QC procedure and the state mean time matrices. As optimal sampling time intervals can be defined those minimizing a QC related cost measure while the rr is acceptable. I developed an algorithm that estimates the rr for any QC sampling time interval of a QC procedure applied to analytical systems with an arbitrary number of critical-failure modes, assuming any failure time and measurement error probability density function for each mode. Furthermore, given the acceptable rr, it can estimate the optimal QC sampling time intervals
Design and Development of a Uni-Directional Solar Collector for Producing Hot Water & Steam
Science is basically "passive" observation of the universe, as it exists to generate knowledge. Engineering is making use of that knowledge to meet human needs by creating machine, systems, process and technologies that have not previously existed. Design and manufacturing are the synthetic part of engineering practice. Manufacturer has received a lot of attention recently for very good economic reasons. The use of renewable energy resources is increasing rapidly. Following this trend, the implementation of large area solar arrays is to be considered. Due to energy drivers that include uncertainty in oil prices and environmental concerns, effective management of energy system is a priority. Energy policy can focus on three areas to improve energy system like renewable energy supply, efficiency improvement and demand reduction. The solar collectors used in the solar heating plants are flat plate solar collectors and compound parabolic solar collector. If the solar irradiance is high the volume flow rate is high, if the solar irradiance is low the volume flow rate is low. When the efficiency of a solar collector is determine often only one volume flow rate. The flat plate solar collector is the simplest form of solar energy collector. It has been widely and efficiency used in many low temperature application in the field of solar energy utilization. This paper emphasis on the maximum utilization of solar power as energy. It can be most often used at various locations such as house and industry. The additional advantage of this project is it can be used as portable solar collector.
DOI: 10.17762/ijritcc2321-8169.15078
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