535 research outputs found
Associations between cannabis use, cannabis use disorder, and mood disorders: longitudinal, genetic, and neurocognitive evidence
Objectives We aimed to evaluate (1) the epidemiological evidence for an association between cannabis use, CUD, and mood disorders; (2) prospective longitudinal, genetic, and neurocognitive evidence of underlying mechanisms; and (3) prognosis and treatment options for individuals with CUD and mood disorders. Methods Narrative review of existing literature is identified through PubMed searches, reviews, and meta-analyses. Evidence was reviewed separately for depression, bipolar disorder, and suicide. Results Current evidence is limited and mixed but suggestive of a bidirectional relationship between cannabis use, CUD, and the onset of depression. The evidence more consistently points to cannabis use preceding onset of bipolar disorder. Shared neurocognitive mechanisms and underlying genetic and environmental risk factors appear to explain part of the association. However, cannabis use itself may also influence the development of mood disorders, while others may initiate cannabis use to self-medicate symptoms. Comorbid cannabis use and CUD are associated with worse prognosis for depression and bipolar disorder including increased suicidal behaviors. Evidence for targeted treatments is limited. Conclusions The current evidence base is limited by the lack of well-controlled prospective longitudinal studies and clinical studies including comorbid individuals. Future studies in humans examining the causal pathways and potential mechanisms of the association between cannabis use, CUD, and mood disorder comorbidity are crucial for optimizing harm reduction and treatment strategies
Evidence for Skyrmion crystallization from NMR relaxation experiments
A resistively detected NMR technique was used to probe the two-dimensional
electron gas in a GaAs/AlGaAs quantum well. The spin-lattice relaxation rate
was extracted at near complete filling of the first Landau level by
electrons. The nuclear spin of As is found to relax much more
efficiently with and when a well developed quantum Hall state with
occurs. The data show a remarkable correlation between the
nuclear spin relaxation and localization. This suggests that the magnetic
ground state near complete filling of the first Landau level may contain a
lattice of topological spin texture, i.e. a Skyrmion crystal
Se and Cu NMR studies of the electronic correlations in CuTiSe ()
We report Se and Cu nuclear magnetic resonance (NMR)
investigation on the charge-density-wave (CDW) superconductor CuTiSe
( and 0.07). At high magnetic fields where superconductivity is
suppressed, the temperature dependence of Se and Cu spin-lattice
relaxation rates 1/T_{1}^{77}1/T_{1}$
vs \emph{T} increases with the Cu doping. This can be described by a modified
Korringa relation which suggests the significance of electronic correlations
and the Se 4\emph{p}- and Ti 3\emph{d}-band contribution to the density of
states at the Fermi level in the studied compounds.Comment: Revised manuscript. Submitted to Journal of Physics: Condensed Matte
Two inequivalent sublattices and orbital ordering in MnV2O4 studied by 51V NMR
We report detailed 51V NMR spectra in a single crystal of MnV2O4. The
vanadium spectrum reveals two peaks in the orbitally ordered state, which arise
from different internal hyperfine fields at two different V sublattices. These
internal fields evolve smoothly with externally applied field, and show no
change in structure that would suggest a change of the orbital ordering. The
result is consistent with the orbital ordering model recently proposed by
Sarkar et al. [Phys. Rev. Lett. 102, 216405 (2009)] in which the same orbital
that is a mixture of t_2g orbitals rotates by about 45 alternately
within and between orbital chains in the I4_1/a tetragonal space group.Comment: 4 pages, 4 figures, title changed, published in PRB as a rapid com
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