607 research outputs found
Design considerations for a wearable monitor to measure finger posture
BACKGROUND: Objective measures of hand function as individuals participate in home and community activities are needed in order to better plan and evaluate rehabilitation treatments. Traditional measures collected in the clinical setting are often not reflective of actual functional performance. Recent advances in technology, however, enable the development of a lightweight, comfortable data collection monitor to measure hand kinematics. METHODS: This paper presents the design analysis of a wearable sensor glove with a specific focus on the sensors selected to measure bend. The most important requirement for the glove is easy donning and removal for individuals with significantly reduced range of motion in the hands and fingers. Additional requirements include comfort and durability, cost effectiveness, and measurement repeatability. These requirements eliminate existing measurement gloves from consideration. Glove construction is introduced, and the sensor selection and glove evaluation process are presented. RESULTS: Evaluation of commercial bend sensors shows that although most are not appropriate for repeatable measurements of finger flexion, one has been successfully identified. A case study for sensor glove repeatability using the final glove configuration and sensors does show a high degree of repeatability in both the gripped and flat hand positions (average coefficient of variability = 2.96% and 0.10%, respectively). CONCLUSION: Measuring functional outcomes in a portable manner can provide a wealth of information important to clinicians for the evaluation and treatment of movement disorders in the hand and fingers. This device is an important step in that direction as both a research and an evaluation method
Accurate Dielectric Response of Solids: Combining the Bethe-Salpeter Equation with the Random Phase Approximation
The Bethe-Salpeter equation (BSE) can provide an accurate description of
low-energy optical spectra of insulating crystals - even when excitonic effects
are important. However, due to high computational costs it is only possible to
include a few bands in the BSE Hamiltonian. As a consequence, the dielectric
screening given by the real part of the dielectric function can be
significantly underestimated by the BSE. Here we show that universally accurate
optical response functions can be obtained by combining a four-point BSE-like
equation for the irreducible polarisability with a two-point Dyson equation
which includes the higher-lying transitions within the random phase
approximation (RPA). The new method is referred to as BSE+. It has a
computational cost comparable to the BSE but a much faster convergence with
respect to the size of the electron-hole basis. We use the method to calculate
refractive indices and electron energy loss spectra for a test set of
semiconductors and insulators. In all cases the BSE+ yields excellent agreement
with experimental data across a wide frequency range and outperforms both BSE
and RPA.Comment: 6 pages, 4 figure
High Mass Triple Systems: The Classical Cepheid Y Car
We have obtained an HST STIS ultraviolet high dispersion Echelle mode
spectrum the binary companion of the double mode classical Cepheid Y Car. The
velocity measured for the hot companion from this spectrum is very different
from reasonable predictions for binary motion, implying that the companion is
itself a short period binary. The measured velocity changed by 7 km/ s during
the 4 days between two segments of the observation confirming this
interpretation. We summarize "binary" Cepheids which are in fact members of
triple system and find at least 44% are triples. The summary of information on
Cepheids with orbits makes it likely that the fraction is under-estimated.Comment: accepted by A
Polaris B, an optical companion of Polaris (alpha UMi) system: atmospheric parameters, chemical composition, distance and mass
We present an analysis of high-resolution spectroscopic observations of
Polaris B, the optical companion of the Polaris Ab system. The star has a
radial velocity V_r of -16.6km/s to -18.9km/s, and a projected rotational
velocity vsini=110 km/s. The derived atmospheric parameters are: Teff=6900K;
logg=4.3; V_t=2.5km/s. Polaris B has elemental abundances generally similar to
those of the Cepheid Polaris A (Usenko et al. 2005a), although carbon, sodium
and magnesium are close to the solar values. At a spectral type of F3V Polaris
B has a luminosity of 3.868L_sun, an absolute magnitude of +3.30mag, and a
distance of 109.5pc. The mass of the star is estimated to be 1.39M_sun, close
to a mass of 1.38+/-0.61M_sun for the recently-resolved orbital periods
companion Polaris Ab observed by Evans et al. (2007).Comment: 6 pages, 3 figures, 1 tabl
Survivors of Chronic Stroke Experience Continued Impairment of Dexterity But Not Strength in the Nonparetic Upper Limb
Objective
To investigate the performance of the less affected upper limb in people with stroke compared with normative values. To examine less affected upper limb function in those whose prestroke dominant limb became paretic and those whose prestroke nondominant limb became paretic. Design
Cohort study of survivors of chronic stroke (7.2±6.7y post incident). Setting
The study was performed at a freestanding academic rehabilitation hospital. Participants
Survivors of chronic stroke (N=40) with severe hand impairment (Chedoke-McMaster Stroke Assessment rating of 2-3 on Stage of Hand) participated in the study. In 20 participants the prestroke dominant hand (DH) was tested (nondominant hand [NH] affected by stroke), and in 20 participants the prestroke NH was tested (DH affected by stroke). Interventions
Not applicable. Main Outcome Measure
Jebsen-Taylor Hand Function Test. Data from survivors of stroke were compared with normative age- and sex-matched data from neurologically intact individuals. Results
When combined, DH and NH groups performed significantly worse on fine motor tasks with their nonparetic hand relative to normative data (PP\u3e.140). Conclusions
Survivors of stroke with severe impairment of the paretic limb continue to present significant upper extremity impairment in their nominally nonparetic limb even years after stroke. This phenomenon was observed regardless of whether the DH or NH hand was primarily affected. Because this group of survivors of stroke is especially dependent on the nonparetic limb for performing functional tasks, our results suggest that the nonparetic upper limb should be targeted for rehabilitation
Polaris the Cepheid returns: 4.5 years of monitoring from ground and space
We present the analysis of 4.5 years of nearly continuous observations of the
classical Cepheid Polaris, which comprise the most precise data available for
this star. We have made spectroscopic measurements from ground and photometric
measurements from the WIRE star tracker and the SMEI instrument on the Coriolis
satellite. Measurements of the amplitude of the dominant oscillation (P = 4
days), that go back more than a century, show a decrease from 120 mmag to 30
mmag (V magnitude) around the turn of the millennium. It has been speculated
that the reason for the decrease in amplitude is the evolution of Polaris
towards the edge of the instability strip. However, our new data reveal an
increase in the amplitude by about 30% from 2003-2006. It now appears that the
amplitude change is cyclic rather than monotonic, and most likely the result of
a pulsation phenomenon. In addition, previous radial velocity campaigns have
claimed the detection of long-period variation in Polaris (P > 40 days). Our
radial velocity data are more precise than previous datasets, and we find no
evidence for additional variation for periods in the range 3-50 days with an
upper limit of 100 m/s. However, in the WIRE data we find evidence of variation
on time-scales of 2-6 days, which we interpret as being due to granulation.Comment: Accepted by ApJ. 8 pages. Quality of figures 1+3+7 degrade
Hubble Space Telescope WFPC-2 Imaging of Cassiopeia A
The young SNR Cassiopeia A was imaged with WFPC-2 through four filters
selected to capture the complete velocity range of the remnant's main shell in
several important emission lines. Primary lines detected were [O III]
4959,5007, [N II] 6583, [S II] 6716,6731 + [O II] 7319,7330 + [O I] 6300,6364,
and [S III] 9069,9532. About 3/4th of the remnant's main shell was imaged in
all four filters. Considerable detail is observed in the reverse-shocked ejecta
with typical knot scale lengths of 0.2"-0.4" (1 - 2 x 10^16 cm). Both bright
and faint emission features appear highly clumped. Large differences in [S III]
and [O III] line intensities indicating chemical abundance differences are also
seen, particularly in knots located along the bright northern limb and near the
base of the northeast jet. A line of curved overlapping filament in the
remnant's northwestern rim appears to mark the location of the remnant's
reverse shock front in this region. Finger-like ejecta structures elsewhere
suggest cases where the reverse shock front is encountering the remnant's
clumped ejecta. Narrow-band [N II] images of the remnant's circumstellar knots
("QSFs") reveal them to be 0.1"-0.6" thick knots and filaments, often with
diffuse edges facing away from the center of expansion. Three color composite
images of the whole remnant and certain sections along with individual filter
enlargements of selected regions of the bright optical shell are presented and
discussed.Comment: 26 pages, 12 figures Accepted to the Astronomical Journa
Do health education initiatives assist socioeconomically disadvantaged populations? : a systematic review and meta-analyses
Background: Health education interventions are considered critical for the prevention and management of conditions of public health concern. Although the burden of these conditions is often greatest in socio-economically disadvantaged populations, the effectiveness of interventions that target these groups is unknown. We aimed to identify and synthesize evidence of the effectiveness of health-related educational interventions in adult disadvantaged populations. Methods: We pre-registered the study on Open Science Framework https://osf.io/ek5yg/. We searched Medline, Embase, Emcare, and the Cochrane Register from inception to 5/04/2022 to identify studies evaluating the effectiveness of health-related educational interventions delivered to adults in socio-economically disadvantaged populations. Our primary outcome was health related behaviour and our secondary outcome was a relevant biomarker. Two reviewers screened studies, extracted data and evaluated risk of bias. Our synthesis strategy involved random-effects meta-analyses and vote-counting. Results: We identified 8618 unique records, 96 met our criteria for inclusion – involving more than 57,000 participants from 22 countries. All studies had high or unclear risk of bias. For our primary outcome of behaviour, meta-analyses found a standardised mean effect of education on physical activity of 0.05 (95% confidence interval (CI) = -0.09–0.19), (5 studies, n = 1330) and on cancer screening of 0.29 (95% CI = 0.05–0.52), (5 studies, n = 2388). Considerable statistical heterogeneity was present. Sixty-seven of 81 studies with behavioural outcomes had point estimates favouring the intervention (83% (95% CI = 73%-90%), p < 0.001); 21 of 28 studies with biomarker outcomes showed benefit (75% (95%CI = 56%-88%), p = 0.002). When effectiveness was determined based on conclusions in the included studies, 47% of interventions were effective on behavioural outcomes, and 27% on biomarkers. Conclusions: Evidence does not demonstrate consistent, positive impacts of educational interventions on health behaviours or biomarkers in socio-economically disadvantaged populations. Continued investment in targeted approaches, coinciding with development of greater understanding of factors determining successful implementation and evaluation, are important to reduce inequalities in health
Vortex Structure Around a Magnetic Dot in Planar Superconductors
The problem of the giant vortex state around a magnetic dot which is embedded
in a superconducting film is investigated. The full non-linear, self-consistent
Ginzburg-Landau equations are solved numerically in order to calculate the free
energy, the order parameter of the host superconductor, the internal magnetic
field due to the supercurrents, the corresponding current density, the
magnetization probed in the vicinity of the dot, and the normal electron
density as a function of the various parameters of the system. We find that, as
we increase the magnetic moment of the dot, higher flux quanta vortex states
become energetically more favorable, as they can better compete with the
external magnetic field via the Meissner effect. In addition to that, they
progressively become closer to each other in energy with direct experimental
consequences, i.e. physical quantities like magnetization may fluctuate when
measured, for example, as a function of a uniform external magnetic field.Comment: text 21 pages (REVTEX), 8 figures available upon reques
Does oral sodium bicarbonate therapy improve function and quality of life in older patients with chronic kidney disease and low-grade acidosis (the BiCARB trial)? Study protocol for a randomized controlled trial
Date of acceptance: 01/07/2015 © 2015 Witham et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. Acknowledgements UK NIHR HTA grant 10/71/01. We acknowledge the financial support of NHS Research Scotland in conducting this trial.Peer reviewedPublisher PD
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