12 research outputs found
Fracture Incidence, Quality of Life, and Back Pain during 18-Months Treatment with Teriparatide in Greek Postmenopausal Women with Osteoporosis: Results from the European Forsteo Observational Study
Objective. To evaluate fracture incidence, effects on health-related quality of life(QoL), back pain (BP) occurrence and treatment compliance in Greek post-menopausal osteoporotic women treated with teriparatide (TPTD) for up to 18 months, in a naturalistic setting. Methods. 301 patients provided baseline information on demographic characteristics, fracture history, osteoporosis-related medication and risk factors. During treatment, QoL and BP severity were evaluated. Results. Mean (SD) age was 69.5 (±8.5) years. Fracture history was reported by 92.5% of patients. Incidence of fractures (per 10,000 patients/years) ranged from 402 during 0–6 months of treatment, to 346 during 12–18 months. All 5 dimensions of QoL showed improvement. At baseline and 18 months, BP was reported by 93.2% and 64.2% of patients, respectively. BP and limitation of activities were quantified as moderate or severe by 89.9% and 62.3% of patients at baseline versus 32.4% and 14.8% at 18 months. Patients on treatment at 6, 12, 17, and 18 months were 92.6%, 88.3%, 79.6%, and 36.5%, respectively. Conclusions. In the Greek EFOS study cohort, patients prescribed TPTD were severely osteoporotic, with considerable health-related problems. Significant improvements in QoL and BP together with low fracture rates and high compliance have been recorded during treatment
Urgent thyroidectomy for acute airway obstruction caused by a goiter in a euthyroid pregnant woman
Pregnancy constitutes a significant factor for thyroid enlargement.
However, acute respiratory failure as a result of airway obstruction
from an enlarged thyroid gland is an unusual incident. The case
presented here concerns a 27-year-old black woman in her 20th
gestational week who underwent an urgent operation for removal of a
nontoxic, multinodular, mildly substernal goiter that was causing severe
upper airway obstruction leading to acute life-threatening respiratory
failure. Diagnosis of an extrathoracic tracheal stenosis was based on
spirometry with analysis of the flow volume curve and was confirmed by
magnetic resonance imaging of the neck. Despite operational risks to the
mother as well as the fetus during gestation, an urgent thyroidectomy
was carried out successfully. The postoperative period progressed
normally and the patient completed her pregnancy with no further
respiratory symptoms
Correction to: Conducting an observational study during an economic crisis: analysis of the treatment and follow-up phase of Greek patients participating in the ExFOS study (Hormones, (2018), 17, 4, (531-540), 10.1007/s42000-018-0077-6)
Unfortunately in the original publication, the affiliation of the author N. Papaioannou was incorrectly provided. The correct affiliation for N. Papaioannou should read as follows: 4 Laboratory for the Research of Musculoskeletal System, School of Medicine, National and Kapodistrian University of Athens, Greece. © 2019, Hellenic Endocrine Society