Dados epidemiológicos do câncer de colo uterino no Rio Grande do Sul

OBJECTIVE: To study the descriptive epidemiology of uterine cervical cancer in the state of Rio Grande do Sul, Brazil, from 1980 to 1994 and to observe the situation of its secondary prevention by citopathology.MATERIALS AND METHODS: Temporal series were constructed with standardized mortality rates using data from the Secretaria de Saúde e Meio Ambiente – SSMA(State of Rio Grande do Sul Health Department) and analyzed through Pearson’s correlation coefficient for temporal series. The results were compared with reports in the literature and data from the Instituto Nacional do Câncer do Brasil .RESULTS: The temporal series demonstrated a tendency to increase (P<0.001) with b=0.09.CONCLUSIONS: Mortality by uterine cervical cancer in the state of Rio Grande do Sul continues to increase, even with the efforts by SSMA to prevent it by citopathology. Suggestions are made to remedy this situation in our stateOBJETIVO: Estudar a epidemiologia descritiva do câncer do colo uterino no Rio Grande do Sul, no período de 1980 a 1994 e verificar a situação da prevenção secundária dessa neoplasia pela citologia.MÉTODOS: Foram construídas séries históricas com índices de mortalidade padronizados pela população mundial, a partir dos dados da Secretaria de Saúde eMeio Ambiente do Rio Grande do Sul e analisadas pelo coeficiente de correlação de Pearson para séries históricas. Os resultados foram comparados com séries anteriores publicadas na literatura e com dados do Instituto Nacional do Câncer do Brasil. RESULTADOS: A série temporal apresentou tendência ascendente (P<0,001) com b=0,09.CONCLUSÕES: A mortalidade por câncer de colo uterino no Rio Grande do Sul continua ascendente, apesar dos esforços da Secretaria de Saúde e Meio Ambiente para sua prevenção pela citopatologia. Sugestões são apresentadas para remediar essa situação no RS

Dados epidemiológicos do câncer de colo uterino no Rio Grande do Sul

OBJECTIVE: To study the descriptive epidemiology of uterine cervical cancer in the state of Rio Grande do Sul, Brazil, from 1980 to 1994 and to observe the situation of its secondary prevention by citopathology.MATERIALS AND METHODS: Temporal series were constructed with standardized mortality rates using data from the Secretaria de Saúde e Meio Ambiente – SSMA(State of Rio Grande do Sul Health Department) and analyzed through Pearson’s correlation coefficient for temporal series. The results were compared with reports in the literature and data from the Instituto Nacional do Câncer do Brasil .RESULTS: The temporal series demonstrated a tendency to increase (P<0.001) with b=0.09.CONCLUSIONS: Mortality by uterine cervical cancer in the state of Rio Grande do Sul continues to increase, even with the efforts by SSMA to prevent it by citopathology. Suggestions are made to remedy this situation in our stateOBJETIVO: Estudar a epidemiologia descritiva do câncer do colo uterino no Rio Grande do Sul, no período de 1980 a 1994 e verificar a situação da prevenção secundária dessa neoplasia pela citologia.MÉTODOS: Foram construídas séries históricas com índices de mortalidade padronizados pela população mundial, a partir dos dados da Secretaria de Saúde eMeio Ambiente do Rio Grande do Sul e analisadas pelo coeficiente de correlação de Pearson para séries históricas. Os resultados foram comparados com séries anteriores publicadas na literatura e com dados do Instituto Nacional do Câncer do Brasil. RESULTADOS: A série temporal apresentou tendência ascendente (P<0,001) com b=0,09.CONCLUSÕES: A mortalidade por câncer de colo uterino no Rio Grande do Sul continua ascendente, apesar dos esforços da Secretaria de Saúde e Meio Ambiente para sua prevenção pela citopatologia. Sugestões são apresentadas para remediar essa situação no RS

Relationship between caga-positive Helicobacter pylori infection and risk of gastric cancer: a case control study in Porto Alegre, RS, Brazil

CONTEXT: Gastric cancer is the second most common cause of cancer related death worldwide. Although Helicobacter pylori has been classified as a class I carcinogen, the presence of infection is not a factor that alone is able to lead to gastric cancer, and one of the possible explanations for this is the existence of different strains of H. pylori with different degrees of virulence. OBJECTIVES: To investigate the association between cagA-positive H. pylori and gastric cancer, using polymerase chain reaction (PCR) for the detection of this bacterial strain. METHODS: Twenty-nine patients with gastric cancer were matched by sex and age (± 5 years) with 58 patients without gastric cancer, submitted to upper gastrointestinal endoscopy. All patients were evaluated for the status of infection by H. pylori (through urease test, histological analysis and PCR for the genes ureA and 16SrRNA) and by cagA-positive strain (through PCR for cagA gene). RESULTS: Evaluating the presence of infection by cagA-positive H. pylori, it was verified that the rate of infection was significantly higher in the group with gastric cancer when compared with the matched controls, occurring in 62.1% and 29.3%, respectively (OR = 3.95; CI 95% 1.543-10.096). CONCLUSIONS: There is an association between cagA-positive H. pylori strain and risk of gastric cancer

Las Provincias : diario de Valencia: Año XLII Número 14798 - 1907 Marzo 05

OBJETIVO: Estudar a epidemiologia descritiva do câncer do colo uterino no Rio Grande do Sul, no período de 1980 a 1994 e verificar a situação da prevenção secundária dessa neoplasia pela citologia. MÉTODOS: Foram construídas séries históricas com índices de mortalidade padronizados pela população mundial, a partir dos dados da Secretaria de Saúde e Meio Ambiente do Rio Grande do Sul e analisadas pelo coeficiente de correlação de Pearson para séries históricas. Os resultados foram comparados com séries anteriores publicadas na literatura e com dados do Instituto Nacional do Câncer do Brasil. RESULTADOS: A série temporal apresentou tendência ascendente (P<0,001) com b=0,09. CONCLUSÕES: A mortalidade por câncer de colo uterino no Rio Grande do Sul continua ascendente, apesar dos esforços da Secretaria de Saúde e Meio Ambiente para sua prevenção pela citopatologia. Sugestões são apresentadas para remediar essa situação no RS.OBJECTIVE: To study the descriptive epidemiology of uterine cervical cancer in the state of Rio Grande do Sul, Brazil, from 1980 to 1994 and to observe the situation of its secondary prevention by citopathology. MATERIALS AND METHODS: Temporal series were constructed with standardized mortality rates using data from the Secretaria de Saúde e Meio Ambiente – SSMA (State of Rio Grande do Sul Health Department) and analyzed through Pearson’s correlation coefficient for temporal series. The results were compared with reports in the literature and data from the Instituto Nacional do Câncer do Brasil . RESULTS: The temporal series demonstrated a tendency to increase (P<0.001) with b=0.09. CONCLUSIONS: Mortality by uterine cervical cancer in the state of Rio Grande do Sul continues to increase, even with the efforts by SSMA to prevent it by citopathology. Suggestions are made to remedy this situation in our state

Prevalence of upper digestive endoscopy and gastric histopathology findings in morbidly obese patients

CONTEXT: The prevalence of obesity has been increasing in modern society. Roux-en-y gastric bypass is a bariatric surgery that involves the exclusion of significant part of the stomach. Atrophy, intestinal metaplasia and gastric cancer have been associated with infection by Helicobacter pylori. OBJECTIVES: To evaluate the presence of endoscopy findings and histological changes in morbid obese patients for the presence of inflammatory cells, inflammatory activity, lymphoid hyperplasia, H. pylori infection, atrophy and intestinal metaplasia in the gastric mucosa. METHODS: Upper digestive endoscopy and gastric histopathological were studied in 126 obese patients in the preoperative evaluation for bariatric surgery. RESULTS: Upper digestive endoscopy abnormalities were diagnosed in 73/126 (57.9%) patients. In three patients (2.4%) the upper gastrointestinal endoscopy diagnosed gastric ulcer and one patient (0.8%) had duodenal ulcer. The histopathological from gastric biopsies of these obese patients showed 65.1% of mucosa inflammation, inflammatory activity in 50.0%, infection by H. pylori in 53.2%, lymphoid hyperplasia in 50.0% and atrophy and/or intestinal metaplasia in 16.7%. CONCLUSIONS: In present study, with routine preoperative upper gastrointestinal endoscopy and histopathological examination, were detected 57.9% patients with endoscopy abnormalities, high prevalence of infection by H. pylori (53%) and 16.7% of gastric atrophy and/or intestinal metaplasia