9,673 research outputs found
Singular normal form for the Painlev\'e equation P1
We show that there exists a rational change of coordinates of Painlev\'e's P1
equation and of the elliptic equation after which these
two equations become analytically equivalent in a region in the complex phase
space where and are unbounded. The region of equivalence comprises all
singularities of solutions of P1 (i.e. outside the region of equivalence,
solutions are analytic). The Painlev\'e property of P1 (that the only movable
singularities are poles) follows as a corollary. Conversely, we argue that the
Painlev\'e property is crucial in reducing P1, in a singular regime, to an
equation integrable by quadratures
Methodological guidelines for the execution of laboratory work in the discipline «Basics of Digital Technologies» for undergraduate students of all NUWEE degree programmes of full-time and part-time forms of education. Module 2
Digital competence is a key competence of the fourth industrial
revolution. Confident mastery and use of digital technologies for
education, employment, work, leisure and participation in public life
is critically important for every citizen of Ukraine.
The aim of the course is to develop skills and abilities in such
areas as: information and media literacy, communication and
collaboration, creating digital content, protecting information in the
digital environment, solving problems and lifelong learning.
The course is based on the European conceptual framework of
digital competences for EU citizens (DigComp 2.1.).
The course "Basics of digital technologies" is divided into two
content modules:
1. Digital technologies for working with text and data;
2. Creation and use of digital content.
Mastering of each module is checked using test tasks in the
Moodle environment.
To successfully pass the course, the student must complete 15
laboratory works and pass two modules. Each laboratory work is
evaluated in the range of 0-4 points. Each module - 0-20 points. To
successfully pass the discipline, a student must score at least 60 points.
The form of final control is an exam
Phase Diagram of the Spin-Orbital model on the Square Lattice
We study the phase diagram of the spin-orbital model in both the weak and
strong limits of the quartic spin-orbital exchange interaction. This allows us
to study quantum phase transitions in the model and to approach from both sides
the most interesting intermediate-coupling regime and in particular the
SU(4)-symmetric point of the Hamiltonian. It was suggested earlier by Li et al
[Phys.Rev.Lett. vol. 81, 3527 (1999)] that at this point the ground state of
the system is a plaquette spin-orbital liquid. We argue that the state is more
complex. There is plaquette order, but it is anisotropic: bonds in one
direction are stronger than those in the perpendicular direction. This order is
somewhat similar to that found recently in the frustrated J_1-J_2 Heisenberg
spin model.Comment: 8 pages, 4 Postscript figure
Structural and biophysical analysis of nuclease protein antibiotics
© 2016 The Author(s); published by Portland Press Limited on behalf of the Biochemical Society. Protein antibiotics (bacteriocins) are a large and diverse family of multidomain toxins that kill specific Gram-negative bacteria during intraspecies competition for resources. Our understanding of the mechanism of import of such potent toxins has increased significantly in recent years, especially with the reporting of several structures of bacteriocin domains. Less well understood is the structural biochemistry of intact bacteriocins and how these compare across bacterial species. Here, we focus on endonuclease (DNase) bacteriocins that target the genomes of Escherichia coli and Pseudomonas aeruginosa, known as E-Type colicins and S-Type pyocins, respectively, bound to their specific immunity (Im) proteins. First, we report the 3.2 Å structure of the DNase colicin ColE9 in complex with its ultra-high affinity Im protein, Im9. In contrast with Im3, which when bound to the ribonuclease domain of the homologous colicin ColE3 makes contact with the translocation (T) domain of the toxin, we find that Im9 makes no such contact and only interactions with the ColE9 cytotoxic domain are observed. Second, we report small-Angle X-ray scattering data for two S-Type DNase pyocins, S2 and AP41, into which are fitted recently determined X-ray structures for isolated domains. We find that DNase pyocins and colicins are both highly elongated molecules, even though the order of their constituent domains differs. We discuss the implications of these architectural similarities and differences in the context of the translocation mechanism of protein antibiotics through the cell envelope of Gram-negative bacteria
Comprehensive study of the magnetic stars HD 5797 and HD 40711 with large chromium and iron overabundances
We present the results of a comprehensive study of the chemically peculiar
stars HD 5797 and HD 40711. The stars have the same effective temperature, Teff
= 8900 K, and a similar chemical composition with large iron (+1.5 dex) and
chromium (+3 dex) overabundances compared to the Sun. The overabundance of
rare-earth elements typically reaches +3 dex. We have measured the magnetic
field of HD 5797. The longitudinal field component Be has been found to vary
sinusoidally between -100 and +1000 G with a period of 69 days. Our estimate of
the evolutionary status of the stars suggests that HD 5797 and HD 40711, old
objects with an age t \approx 5 \times 108 yr, are near the end of the core
hydrogen burning phase.Comment: 26 pages, 5 Encapsulated Postscript figure
Toward a Midisuperspace Quantization of LeMaitre-Tolman-Bondi Collapse Models
LeMa\^\i tre-Tolman-Bondi models of spherical dust collapse have been used
and continue to be used extensively to study various stellar collapse
scenarios. It is by now well-known that these models lead to the formation of
black holes and naked singularities from regular initial data. The final
outcome of the collapse, particularly in the event of naked singularity
formation, depends very heavily on quantum effects during the final stages.
These quantum effects cannot generally be treated semi-classically as quantum
fluctuations of the gravitational field are expected to dominate before the
final state is reached. We present a canonical reduction of LeMa\^\i
tre-Tolman-Bondi space-times describing the marginally bound collapse of
inhomogeneous dust, in which the physical radius, , the proper time of the
collapsing dust, , and the mass function, , are the canonical
coordinates, , and on the phase space. Dirac's
constraint quantization leads to a simple functional (Wheeler-DeWitt) equation.
The equation is solved and the solution can be employed to study some of the
effects of quantum gravity during gravitational collapse with different initial
conditions.Comment: 9 pages, 1 figure, Latex file. Minor corrections made. A general
solution of the constraints is presented. Revised version to appear in Phys.
Rev.
The first WASP public data release
The WASP (wide angle search for planets) project is an exoplanet transit survey that has been automatically taking wide field images since 2004. Two instruments, one in La Palma and the other in South Africa, continually monitor the night sky, building up light curves of millions of unique objects. These light curves are used to search for the characteristics of exoplanetary transits. This first public data release (DR1) of the WASP archive makes available all the light curve data and images from 2004 up to 2008 in both the Northern and Southern hemispheres. A web interface () to the data allows easy access over the Internet. The data set contains 3 631 972 raw images and 17 970 937 light curves. In total the light curves have 119 930 299 362 data points available between them
Dark pair coherent states of the motion of a trapped ion
We propose a scheme for generating vibrational pair coherent states of the
motion of an ion in a two-dimensional trap. In our scheme, the trapped ion is
excited bichromatically by three laser beams along different directions in the
X-Y plane of the ion trap. We show that if the initial vibrational state is
given by a two-mode Fock state, the final steady state, indicated by the
extinction of the fluorescence emitted by the ion, is a pure state. The
motional state of the ion in the equilibrium realizes that of the
highly-correlated pair coherent state.Comment: 14 pages, 3 figure
Structures of the Ultra-High-Affinity Protein-Protein Complexes of Pyocins S2 and AP41 and Their Cognate Immunity Proteins from Pseudomonas aeruginosa
© 2015 The Authors. Published by Elsevier Ltd. How ultra-high-affinity protein-protein interactions retain high specificity is still poorly understood. The interaction between colicin DNase domains and their inhibitory immunity (Im) proteins is an ultra-high-affinity interaction that is essential for the neutralisation of endogenous DNase catalytic activity and for protection against exogenous DNase bacteriocins. The colicin DNase-Im interaction is a model system for the study of high-affinity protein-protein interactions. However, despite the fact that closely related colicin-like bacteriocins are widely produced by Gram-negative bacteria, this interaction has only been studied using colicins from Escherichia coli. In this work, we present the first crystal structures of two pyocin DNase-Im complexes from Pseudomonas aeruginosa, pyocin S2 DNase-ImS2 and pyocin AP41 DNase-ImAP41. These structures represent divergent DNase-Im subfamilies and are important in extending our understanding of protein-protein interactions for this important class of high-affinity protein complex. A key finding of this work is that mutations within the immunity protein binding energy hotspot, helix III, are tolerated by complementary substitutions at the DNase-Immunity protein binding interface. Im helix III is strictly conserved in colicins where an Asp forms polar interactions with the DNase backbone. ImAP41 contains an Asp-to-Gly substitution in helix III and our structures show the role of a co-evolved substitution where Pro in DNase loop 4 occupies the volume vacated and removes the unfulfilled hydrogen bond. We observe the co-evolved mutations in other DNase-Immunity pairs that appear to underpin the split of this family into two distinct groups
Shapiro Effect as a Possible Cause of the Low-Frequency Pulsar Timing Noise in Globular Clusters
A prolonged timing of millisecond pulsars has revealed low-frequency
uncorrelated noise, presumably of astrophysical origin, in the pulse arrival
time (PAT) residuals for some of them. In most cases, pulsars in globular
clusters show a low-frequency modulation of their rotational phase and spin
rate. The relativistic time delay of the pulsar signal in the curved space time
of randomly distributed and moving globular cluster stars (the Shapiro effect)
is suggested as a possible cause of this modulation.
Given the smallness of the aberration corrections that arise from the
nonstationarity of the gravitational field of the randomly distributed ensemble
of stars under consideration, a formula is derived for the Shapiro effect for a
pulsar in a globular cluster. The derived formula is used to calculate the
autocorrelation function of the low-frequency pulsar noise, the slope of its
power spectrum, and the behavior of the statistic that characterizes
the spectral properties of this noise in the form of a time function. The
Shapiro effect under discussion is shown to manifest itself for large impact
parameters as a low-frequency noise of the pulsar spin rate with a spectral
index of n=-1.8 that depends weakly on the specific model distribution of stars
in the globular cluster. For small impact parameters, the spectral index of the
noise is n=-1.5.Comment: 23 pages, 6 figure
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