Validation of the EPACODI-1 Scale: University Students’ Perceptions of Inclusive Education

In the last fifteen years, changes have been taking place in education systems at the international and national levels that aim to achieve, in the near future, the objectives set by the UN International Convention on the Rights of Persons with Disabilities (hereafter CRPD). Spain is no stranger to these objectives, as recognized in the new Organic Law for the Modification of the Law on the Organization of Education. This situation makes it necessary to know the perceptions that professionals in training (about to graduate) from faculties of education have about the legal content established by articles 4.1.i and 24 of the CRPD on inclusive education. In order to ascertain these perceptions, the EPACO-DI-1 instrument was used in a quantitative and confirmatory study by means of a multivariate factor analysis (CFA), applying the parallel estimation method of ordinary least squares (OLS) and principal axes with polychoric correlation and promax oblique rotation. This study involved 552 fourth-year students between the ages of 21 and over 45 from the specializations offered by the Faculty of Education of the University of Murcia. The obtained results are consistent and show the validity of the EPACODI-1 scale for determining the perceptions of professionals in training on inclusive education.DIDE research group of the Department of Didactics and School Organization of the Faculty of Education of the University of Murci

Aplicación de estrategias de aprendizaje innovadoras para generar comprensión en la asignatura de Filosofía en los estudiantes de 11mo grado del Colegio Público 14 de Septiembre de Managua

La presente investigación consistió en la aplicación de estrategias de aprendizaje innovadoras en el proceso de enseñanza aprendizaje, con las cuales se pretende generar comprensión en los estudiantes de undécimo grado en la asignatura de Filosofía en el Colegio Público 14 de Septiembre de la ciudad de Managua. Cabe destacar que esta asignatura es poca atractiva para los estudiantes debido al rol del docente tradicionalista y a la carencia de enfoque que se le da en relación al ámbito social. Este trabajo se apoya en el enfoque constructivista, resaltando que al incorporar nuevas estrategias se producen cambios significativos en las estructuras mentales, estos cambios son progresivos y ayudan al estudiante a estar motivados a aprender y relacionar situaciones de la vida diaria con los conceptos que ya poseen, permitiendo un aprendizaje a largo plazo, es decir lograr un aprendizaje en conjunto que los ayude a desarrollar un criterio personal teniendo una mejor perspectiva del ambiente social en el que se encuentren. También se trabajó con diversas teorías constructivistas, se habla de la comprensión, desarrollo de competencias, visión tripartita de los contenidos y las estrategias didácticas innovadoras (es decir nuevas o adecuadas a los contextos), todo esto con el fin de mejorar los modelos y prácticas de enseñanza actuales, aplicados a una unidad didáctica. En este proceso de intervención didáctica se utilizó diarios de campo y cámaras fotográficas para tener mayor valide

El efecto de las redes organizativas sobre los festivales en pequeñas ciudades

Los festivales son un tipo de evento que ofrece verdaderas oportunidades para la activación urbana en ciudades de pequeño o mediano tamaño. Sin embargo, estas ciudades explotan de manera muy diversa este tipo de oportunidades. Las redes involucradas en estos eventos culturales determinan en cierta medida sus beneficios potenciales y también sus restricciones. Hemos analizado tres festivales que se llevan a cabo en destinos turísticos españoles de pequeño tamaño. Nuestros resultados confirman la existencia de diferentes mecanismos de gobernabilidad de las redes involucradas en los festivales. Las implicaciones de este trabajo pueden ser útiles, tanto para el diseño de políticas como para la organización individual de los eventos.Events such as festivals offer considerable opportunities for urban activation in medium or small cities. However, cities significantly vary in the degree they exploit these opportunities. This paper analyzes this relevant question adopting a network perspective. We argue that networks of people and organizations involved in a cultural event determine to some extent its potential benefits and restraints. We have illustrated our argumentation though three festivals held in minor urban touristic destinations in Spain. Findings confirm the existence of different modes of network governance in festivals. Implications may be useful for both policy makers and individual organizations

Bosentan and oral anticoagulants in HIV patients: what we can learn of cases reported so far

Pulmonary arterial hypertension is an infrequent but nevertheless serious life-threatening severe complication of HIV infection. It can be treated with bosentan and oral anticoagulants. Bosentan could induce the acenocoumarol metabolism and it increases the INR values. Until now, no study of interaction between bosentan and oral anticoagulants in HIV patients has reported. So we present a case of this interaction between these drugs and we reviewed MEDLINE to identify all the papers published so far. In our case, several weeks after increasing dose of bosentan acenocoumarol dose had to be progressively increased to 70 mg/week (+33%) without obtaining an adequate INR level (2.0–3.0). Forty-nine days later, we achieved a therapeutic INR with 90 mg/week of warfarin. The use of bosentan and oral anticoagulants together in these patients require a closer monitoring during first weeks of treatment, after increasing the bosentan dose and even during longer periods of time

Estimation of the Genetic Components of (Co)variance and Preliminary Genome-Wide Association Study for Reproductive Efficiency in Retinta Beef Cattle

In this study, we analyzed the variation of reproductive efficiency, estimated as the deviation between the optimal and real parity number of females at each stage of the cow’s life, in 12,554 cows belonging to the Retinta Spanish cattle breed, using classical repeatability and random regression models. The results of the analyses using repeatability model and the random regression model suggest that reproductive efficiency is not homogeneous throughout the cow’s life. The h2 estimate for this model was 0.30, while for the random regression model it increased across the parities, from 0.24 at the first calving to 0.51 at calving number 9. Additionally, we performed a preliminary genome-wide association study for this trait in a population of 252 Retinta cows genotyped using the Axiom Bovine Genotyping v3 Array. The results showed 5 SNPs significantly associated with reproductive efficiency, located in two genomic regions (BTA4 and BTA28). The functional analysis revealed the presence of 5 candidate genes located within these regions, which were previously involved in different aspects related to fertility in cattle and mice models. This new information could give us a better understanding of the genetic architecture of reproductive traits in this species, as well as allow us to accurately select more fertile cows

Connection between the Jurassic oceanic lithosphere of the Gulf of Cádiz and the Alboran slab imaged by Sp receiver functions

We investigate the lithospheric structure beneath the Gibraltar arc (western Mediterranean) using S-wave receiver functions (SRFs). From a dense network deployed in the Ibero-Maghrebian region during different seismic surveys, we calculated ~11,000 SRFs that sample the upper mantle detecting the lithosphere-asthenosphere boundary (LAB). The observed seismic LAB belongs to different lithospheric domains: Iberian and African forelands, Alboran domain, and Atlantic Ocean. Common conversion point (CCP) migrated profiles show the geometrical relation among them. Under the Strait of Gibraltar, we observe a deep LAB (~150 km). It can be associated with Jurassic-age lithosphere of ~120 km thickness, one of the thickest ever reported in oceanic environments. There is an abrupt offset between the oceanic LAB and the shallow (80-km-deep) continental LAB of the Iberian foreland, suggesting displacement along a former transform fault. The northwestern African continental LAB is 90–100 km deep. The oceanic LAB under the Gibraltar arc continues to ~180 km depth beneath the Alboran Sea, showing the connection between the Alboran slab and the oceanic lithosphere in the central Gulf of Cádiz. This geometry agrees with an ~200-km-wide corridor of oceanic lithosphere between the central Atlantic and the Alpine Tethys, developed during the Middle–Late Jurassic. Our results support the proposed westward rollback of an oceanic east-dipping slab, which has continuity at least to the central Gulf of Cádiz.This work was supported by the Spanish national projects CGL2015-67130-C2-2-R/FEDER and CGL2012-31472

Preservation of the Iberian Tethys paleomargin beneath the eastern Betic mountain range

We are grateful to the staff involved in the TransCorBe project. The Geophysical Instrument Pool at GFZ-Potsdam provided most of the seismic equipment. We are grateful to Christian Haberland for his support. We want to thank two anonymous reviewers for the careful reading of the manuscript and the interesting and constructive criticism they provided. This work was funded by the Spanish State Research Agency (SRA) under the grant PID2019-109608GB I00/SRA/10.13039/501100011033, FEDER/MINECO project CGL2015-67130-C2-2-R, FEDER/Junta de Andalucia project A-RNM-421-UGR18 and research group RNM104 of the Junta de Andalucia. The Granada University/CBUA funding for open access charge.We obtain P-wave receiver functions from teleseismic earthquake recordings at a dense seismic broadband transect, deployed along 170 km across the Betic mountain range in southeastern Spain. Migrated images show the crustal structure of the orogen in detail. In particular, they reveal the situation of the subducted Iberian paleomargin, with full preservation of the proximal domain and the 50 km wide necking domain. Crustal thinning across the necking domain affects mainly the lower continental crust. The Variscan crust of the Tethys margin is bending downward beneath the Betics, reaching 45 km depth, and terminates abruptly at a major slab tear. The distal domain of the paleomargin cannot be reconstructed, but the migrated section suggests that material has been exhumed through the subduction channel and integrated into the Betic orogen. This supports an origin of the HP-LT Nevado-Filabride units from subducted, hyperextended Variscan crust. According to our profile, the present-day eastern Betics appear to have a much more significant contribution from metamorphic Iberian crust than previously thought.Geophysical Instrument Pool at GFZ-Potsdam - Spanish State Research Agency (SRA) PID2019-109608GB I00/SRA/10.13039/501100011033Spanish Government CGL2015-67130-C2-2-RFEDER/Junta de Andalucia project A-RNM-421-UGR18 RNM104Junta de Andaluci

Clinical metagenomic analysis and Cancer

After seven years of periodic controls by the SEIMC (Spanish Society of Infectious Diseases and Clinical Microbiology), it can be affirmed that the analysis is capable of detecting microorganisms in any type of sample (Blood, CSF, Saliva, BAL, Urine, Sputum, Faeces, Tissues, Prosthetic Material, Exudates, Swabs, Etc…), it requires a small amount of sample, it identifies more than 77,000 pathogens in a single test, simultaneously detects Archaea, G+ and G- Bacteria, Fungi, Viruses, Protists and parasites, it detects nonculturable pathogens and those that revert to false negatives, it is not affected by inhibition by antibiotics or other causes, resistance to antibiotics and antimycotics are detected, results are obtained in 24 hours, it is the most sensitive and reliable direct microbial identification technique and specific today. The analysis is 87% more sensitive than a culture, 99% reliable in gender determination, 91% reliable in sensitivity, increases the rate of accurate diagnosis of infections by more than 50%, as it is NGS sequencing it is more sensitive, specific and reliable than 16s and 18s sequencing. The test is highly useful for detecting microorganisms associated with cancer.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

Deshidratación de glucosa a 5-hidroximetilfurfural mediante sílices mesoporosas dopadas con circonio

La búsqueda de nuevas fuentes de carbono se ha convertido en un objetivo esencial debido tanto a la disminución de las reservas de combustibles fósiles, como a la contaminación que su uso conlleva. El empleo de la biomasa lignocelulósica como fuente de carbono renovable es una interesante alternativa, ya que es muy abundante en la naturaleza. La lignocelulosa se encuentra formada por celulosa (40-50%), hemicelulosa (25-30%) y lignina (15-30%). En la actualidad, resulta de gran interés la valorización de glucosa, carbohidrato presente en la celulosa, a productos de alto valor añadido como el 5- hidroximetilfurfural (HMF), el cual se considera molécula plataforma derivada de la plataforma de azúcares. La deshidratación de glucosa a HMF requiere la presencia de centros ácidos, tanto de Lewis como Brönsted, ya que la acidez de Lewis cataliza la isomerización de glucosa a fructosa, mientras que la acidez de Brönsted promueve la deshidratación de fructosa a HMF. El objetivo de este trabajo es la incorporación de circonio sobre diferentes sílices mesoporosas para su uso como catalizadores sólidos ácidos en la reacción de deshidratación de glucosa a HMF, donde se han optimizado las condiciones de reacción para obtener un alto rendimiento en dicho producto. Se ha demostrado que diferentes sílices mesoporosas dopadas con Zr, utilizadas como catalizadores sólidos ácidos, son activas para la obtención de HMF, siendo el Zr-HMS el que presenta un comportamiento más interesante debido a su excelente actividad catalítica a tiempos cortos de reacción. Asimismo, este catalizador proporciona un alto rendimiento en HMF (40%) incluso a más baja temperatura.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

Conversión de celulosa en 5-hidroximetilfurfural en presencia de Zr-KIT-6

El 5-hidroximetilfurfural (HMF) es un producto químico de alto valor añadido que puede ser transformado en numerosos productos químicos y biocombustibles. Se han realizado numerosos esfuerzos para obtener HMF a partir de carbohidratos procedentes de la biomasa lignocelulósica, como glucosa y fructosa, mediante su deshidratación en presencia de catalizadores ácidos. El objetivo de este trabajo es disminuir la cristalinidad de la celulosa mediante un tratamiento mecánico y estudiar su hidrólisis y deshidratación a HMF utilizando como catalizador una sílice mesoporosa KIT-6 dopada con Zr, y posteriormente sulfatada. Se sintetizaron una sílice KIT-6 sin y con dopado con Zr (relación molar Si/Zr= 14: Zr-KIT-6). La sulfatación se realizó con H2SO4 1 M a temperatura ambiente, y posterior tratamiento térmico a 300ºC. El pretratamiento mecánico de diferentes celulosas se ha llevado a cabo mediante un molino de bolas, teniendo en cuenta para el estudio tanto el tiempo de molienda de la celulosa como la cantidad de CaCl2 añadida. Mediante DRX a bajo ángulo se comprobó que el sólido KIT-6 presenta un pico a 2θ=0.87º correspondiente a la simetría cúbica Ia3d. Esta señal se observa también para Zr-KIT-6 a pesar de que disminuye ligeramente su intensidad, por lo que la estructura se mantiene tras la incorporación de Zr. Por otro lado, las muestras de celulosa pretratadas con diferentes condiciones se analizaron mediante DRX a alto ángulo. Se observa que tanto el tiempo de molienda como la adición de CaCl2 durante el pretratamiento son factores que favorecen la pérdida de cristalinidad de la celulosa, pasando de un 33-35% a un 19%, por lo que este pretratamiento podría facilitar su posterior hidrólisis. La reacción de deshidratación de glucosa, procedente de la hidrólisis de la celulosa, se ha realizado en un sistema agua/MIBK, en presencia de CaCl2 para minimizar las reacciones secundarias de degradación del HMF formado.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tec