346 research outputs found

    User Analysis Mechanisms based Mobile Fitness System

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    Modern men have health problems caused by lack of exercise than in the past. But most modern people do not know what to do exercise. Mobile systems for fitness to solve this problem have been developed. In this paper, by analyzing the user's BMI (Body Mass Index) Index and BMR (Basal Metabolic Rate) value, the data is made available. The processed data is provided to the user which proposes the right exercise and the appropriate level of exercise intensity, for exercise machines. This is different from detecting the movement, like the existing system, and a fitness value showing the calorie consumption caused. Thus the user is considered to be able to efficiently proceed to a movement based on the provided data

    Refining Historical earthquake Data Through Modeling and Scale Model Tests

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    This study was performed for the reevaluation of historical earthquake records which occurred in Korea through tests and numerical analyses. For the scale model tests, static and cyclic lateral load tests on wooden frames that constitute a Korean ancient commonerā€™s house were conducted. Full-scale models of two types of frames were used for testing. Two 1:4 scale models were tested for rock and soil foundation conditions. Scaled real earthquake time histories were inputted for the tests. The peak ground acceleration (PGA) at the collapse of the house at the soil site was 0.25g, whereas PGA for moderate damage at the rock site was 0.6g. The intensity of major historical earthquake records related with house collapses was reevaluated based on the results of these scale mode1 tests. The magnitudes of historical earthquake records related with house collapses were estimated considering the magnitude, epicentral distance, soil condition and aging of the house. Eighteen artificial time histories for magnitudes 6-8, epicentral distances 5 km - 350 km and hard and soft soil condition were generated. The aging effects of the house was modeled as the lateral loading capacity of wooden frames represented by hysteretic stiffness decreased linearly with time

    Minimally Invasive Irrigation for Lumbar Spinal Epidural Abscess using a Trans-Sacral Epiduroscopic Laser Decompression Catheter

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    We describe a case of a spinal epidural abscess that was successfully treated with minimally invasive irrigation using trans-sacral epiduroscopic laser decompression (SELD) catheter. A 66-year-old man experienced aggravating right leg pain and lower back pain for 1 month despite receiving several pain blocks at a local hospital. Magnetic resonance imaging scans showed annular fissure and bulging disc at the L4/5 level. Therefore, we decided to treat the L4/5 lesion using SELD. Laboratory studies demonstrated leukocytosis and elevated C-reactive protein level. However, we did not pay attention to the abnormal laboratory values before SELD. During SELD, we found a yellowish epidural abscess and pus drainage. Therefore, we irrigated the epidural abscess using an SELD catheter. His low back pain was relieved dramatically immediately after the procedure. The spinal epidural abscess completely resolved after 20 days of antibiotic treatment. Minimally invasive irrigation and drainage using a SELD catheter and intravenous antibiotic therapy are helpful for the treatment of spinal epidural abscess

    PANDANGAN HUKUM ISLAM TERHADAP HUTANG UANG DENGAN PENGEMBALIAN SEHARGA SAPI DI DESA PRIJEKNGABLAK KECAMATAN KARANGGENENG KABUPATEN LAMONGAN

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    Hasil penelitian tehadap hutang uang dengan pengembalian seharga sapi di Desa Prijekngablak terjadi melalui dua bentuk penilaian. Pertama terjadi pada dua pihak muqrid dan muqtarid menggunakan sapi milik muqrid yang dijadikan ukuran hutang uang. Kedua pada tiga pihak muqrid, muqtarid dan pemilik sapi menggunakan sapi milik pihak ketiga dikarenakan muqrid memiliki sapi ataupun tidak memiliki tetapi tidak ingin dijadikan ukuran hutang sehingga sapi milik pihak ketiga yang dijadikan ukuran. Jangka waktu yang ditentukan dalam hutang uang yakni 1 tahun. Pengembalian pinjaman harus sesuai dengan seharga sapi yang telah laku terjual. Pihak ketiga akan mendapat komisi dari pengembalian pinjaman sebesar dua puluh lima persen sebagai upah sapinya telah digunakan sebagai ukuran hutang. Apabila sapi yang digunakan sebagai ukuran hutang mati ataupun hilang maka muqtarid hanya mengembalikan pokok pinjaman saja. Berdasarkan hasil penelitian di atas menyimpulkan bahwa praktik hutang uang dengan pengembalian seharga sapi tidak sesuai dengan aturan yang sudah ditentukan menurut hukum Islam karena penambahan dalam pokok pinjaman ini bisa terjerumus dalam riba. Riba merupakan salah satu bentuk kedzhaliman yang tidak sesuai dengan asas berakad dalam Islam yakni asas keadilan. Islam melarang mengambil atau memakan harta orang lain secara tidak sah (dengan cara batil) dan tanpa adanya kerelaan antara kedua belah pihak yang melakukan perjanjian

    Acceleration Effect of CuCN in Ag Electroplating for Ultralarge-Scale Interconnects

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    The addition of CuCN accelerated the deposition rate in cyanide-based Ag electroplating. The catalytic effect came from the high-order complexation of Cu with the free CNāˆ’ ions in electrolyte. It changed the equilibrium state of the electrolyte, presented as an increase in the amount of Ag CN 2 āˆ’ compared to Ag CN 3 2āˆ’. Because Ag CN 2 āˆ’ could be reduced more easily, Ag electroplating was accelerated. Fourier transform infrared analysis showed the equilibrium change with the increase in Ag CN 2 āˆ’ peak according to the CuCN addition. For superfilling, it is necessary to localize the complexation on the Cu surface.This work was supported by the Korea Science and Engineering Foundation through the Research Center for Energy Conversion and Storage RCECS , Dongbu HiTeK, and also by the Institute of Chemical Processes ICP

    Progression of Prostate Cancer Despite an Extremely Low Serum Level of Prostate-Specific Antigen

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    A 61-year-old man who had been diagnosed with prostate cancer 9 years ago and had been treated with pelvic irradiation and intermittent androgen deprivation therapy visited the emergency room because of back pain and weakness in both legs. Spine magnetic resonance imaging showed a lumbar epidural mass and spine metastasis. The whole-body workup revealed multiple metastases to the lymph nodes, bone, liver, and lung. The serum prostate-specific antigen was 0.02 ng/ml. He underwent laminectomy, posterior fixation, and epidural mass excision, and metastatic adenocarcinoma from the prostate was diagnosed. The patient underwent 1 cycle of docetaxel-based chemotherapy. More chemotherapy could not be done because of his general weakness. The patient died one month later of multiple organ failure

    Okanin, a chalcone found in the genus Bidens, and 3-penten-2-one inhibit inducible nitric oxide synthase expression via heme oxygenase-1 induction in RAW264.7 macrophages activated with lipopolysaccharide

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    Excess production of nitric oxide by activated macrophages via inducible nitric oxide synthase leads to the development of various inflammatory diseases. Heme oxygenase-1 expression via activation of nuclear factor-erythroid 2-related factor 2 inhibits nitric oxide production and inducible nitric oxide synthase expression in activated macrophages. Okanin is one of the most abundant chalcones found in the genus Bidens (Asteraceae) that is used as various folk medications in Korea and China for treating inflammation. Here, we found that okanin (possessing the Ī±-Ī² unsaturated carbonyl group) induced heme oxygenase-1 expression via nuclear factor-erythroid 2-related factor 2 activation in RAW264.7 macrophages. 3-Penten-2-one, of which structure, as in okanin, possesses the Ī±-Ī² unsaturated carbonyl group, also induced nuclear factor-erythroid 2-related factor 2-dependent heme oxygenase-1 expression, while both 2-pentanone (lacking a double bond) and 2-pentene (lacking a carbonyl group) were virtually inactive. In lipopolysaccharide-activated RAW264.7 macrophages, both okanin and 3-penten-2-one inhibited nitric oxide production and inducible nitric oxide synthase expression via heme oxygenase-1 expression. Collectively, our findings suggest that by virtue of its Ī±-Ī² unsaturated carbonyl functional group, okanin can inhibit nitric oxide production and inducible nitric oxide synthase expression via nuclear factor-erythroid 2-related factor 2-dependent heme oxygenase-1 expression in lipopolysaccharide-activated macrophages

    Trans-1,3-diphenyl-2,3-epoxypropan-1-one, a chalcone derivative, induces apoptosis via ROS-mediated down-regulation of Bcl-xL in human leukemia HL-60 cells

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    The anticancer effects of trans-1,3-diphenyl-2,3-epoxypropan-1-one (DPEP), a chalcone derivative, were investigated in human leukemia HL-60 cells. Treatment of HL-60 cells with various concentration of DPEP resulted in a sequence of events characteristic of apoptosis, including loss of cell viability, morphological changes, and increased sub-G1 DNA content. We demonstrated that DPEP elevates reactive oxygen species (ROS) levels in HL-60 cells, and that the ROS scavenger N-acetylcysteine (NAC) could block DPEP-induced ROS generation and apoptosis. Western blot analysis revealed that DPEP inhibits Bcl-xL expression, leading to caspase-3 activation and poly-ADP-ribose polymerase (PARP) cleavage, thereby inducing apoptosis. However, NAC pretreatment significantly inhibited the activation of caspase-3 and PARP cleavage and reduced Bcl-xL levels. These findings provide the first evidence that DPEP may inhibit the growth of HL-60 cells and induce apoptosis through a ROS-mediated Bcl-xL pathway
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