31 research outputs found
Model Analysis of Time Reversal Symmetry Test in the Caltech Fe-57 Gamma-Transition Experiment
The CALTECH gamma-transition experiment testing time reversal symmetry via
the E2/M1 mulipole mixing ratio of the 122 keV gamma-line in Fe-57 has already
been performed in 1977. Extending an earlier analysis in terms of an effective
one-body potential, this experiment is now analyzed in terms of effective one
boson exchange T-odd P-even nucleon nucleon potentials. Within the model space
considered for the Fe-57 nucleus no contribution from isovector rho-type
exchange is possible. The bound on the coupling strength phi_A from effective
short range axial-vector type exchange induced by the experimental bound on
sin(eta) leads to phi_A < 10^{-2}.Comment: 5 pages, RevTex 3.
Measurement of the Positive Muon Anomalous Magnetic Moment to 0.46 ppm
We present the first results of the Fermilab Muon g-2 Experiment for the
positive muon magnetic anomaly . The anomaly is
determined from the precision measurements of two angular frequencies.
Intensity variation of high-energy positrons from muon decays directly encodes
the difference frequency between the spin-precession and cyclotron
frequencies for polarized muons in a magnetic storage ring. The storage ring
magnetic field is measured using nuclear magnetic resonance probes calibrated
in terms of the equivalent proton spin precession frequency
in a spherical water sample at 34.7C. The
ratio , together with known fundamental
constants, determines
(0.46\,ppm). The result is 3.3 standard deviations greater than the standard
model prediction and is in excellent agreement with the previous Brookhaven
National Laboratory (BNL) E821 measurement. After combination with previous
measurements of both and , the new experimental average of
(0.35\,ppm) increases the
tension between experiment and theory to 4.2 standard deviationsComment: 10 pages; 4 figure
Intraocular Pressure–Lowering Effect of 0.005% Latanoprost with Two Different Dosing Regimens
Two Sets of Interacting Collagens Form Functionally Distinct Substructures within a Caenorhabditis elegans Extracellular Matrix
A ubiquitous feature of collagens is protein interaction, the trimerization of monomers to form a triple helix followed by higher order interactions during the formation of the mature extracellular matrix. The Caenorhabditis elegans cuticle is a complex extracellular matrix consisting predominantly of cuticle collagens, which are encoded by a family of ∼154 genes. We identify two discrete interacting sets of collagens and show that they form functionally distinct matrix substructures. We show that mutation in or RNA-mediated interference of a gene encoding a collagen belonging to one interacting set affects the assembly of other members of that set, but not those belonging to the other set. During cuticle synthesis, the collagen genes are expressed in a distinct temporal series, which we hypothesize exists to facilitate partner finding and the formation of appropriate interactions between encoded collagens. Consistent with this hypothesis, we find for the two identified interacting sets that the individual members of each set are temporally coexpressed, whereas the two sets are expressed ∼2 h apart during matrix synthesis
Newcastle disease virus fusion and haemagglutinin-neuraminidase gene motifs as markers for viral lineage
Reverse transcriptase polymerase chain reaction was used to generate sequence data for 91 Australian Newcastle disease viruses (NDV) isolated from 1932 to 2000 covering the cleavage site of the fusion (F) protein and the C-terminus of the haemagglutinin-neuraminidase (HN) protein. Comparison of sequences at these two sites indicates distinct evolutionary relationships between these viruses. Typically, HN gene relationships revealed by phylogenetic analyses were also maintained in comparisons between F gene cleavage sites; however, the former analyses appeared to give a clearer indication of the lineage of a virus isolate. This data supports and extends earlier observations in that there is no evidence for gene exchange by recombination but that different strains appear to have evolved through synonymous mutations. Inter-relationships, especially between Australian NDV isolates, appear to be associated with lineages having the same C-terminal HN extensions rather than associated with virulence of the virus. A proposed mechanism for this observation is discussed
Predictive value of cord blood IgE levels in 'at-risk' newborn babies and influence of type of feeding
The Marine Biological Station on Puffin Island (Ynys Seiriol) and the work of the Liverpool Marine Biology Committee (1887–1892)
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Impact of Amerind ancestry and FADS genetic variation on omega-3 deficiency and cardiometabolic traits in Hispanic populations
Long chain polyunsaturated fatty acids (LC-PUFAs) have critical signaling roles that regulate dyslipidemia and inflammation. Genetic variation in the FADS gene cluster accounts for a large portion of interindividual differences in circulating and tissue levels of LC-PUFAs, with the genotypes most strongly predictive of low LC-PUFA levels at strikingly higher frequencies in Amerind ancestry populations. In this study, we examined relationships between genetic ancestry and FADS variation in 1102 Hispanic American participants from the Multi-Ethnic Study of Atherosclerosis. We demonstrate strong negative associations between Amerind genetic ancestry and LC-PUFA levels. The FADS rs174537 single nucleotide polymorphism (SNP) accounted for much of the AI ancestry effect on LC-PUFAs, especially for low levels of n-3 LC-PUFAs. Rs174537 was also strongly associated with several metabolic, inflammatory and anthropomorphic traits including circulating triglycerides (TGs) and E-selectin in MESA Hispanics. Our study demonstrates that Amerind ancestry provides a useful and readily available tool to identify individuals most likely to have FADS-related n-3 LC-PUFA deficiencies and associated cardiovascular risk. © 2021, The Author(s).Open access journalThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at [email protected]