2,313 research outputs found

    Self-adaptive hierarchic finite element solution of the one-dimensional unsaturated flow equation

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    The advantages associated with the use of self-adaptive methods for the solution of problems which require the prediction of a frontal position in time are well known. In this paper a self-adaptive finite element solution for the non-linear unsaturated flow equation is developed using hierarchic p -version enrichment of the interpolating space. Additional computational advantages are demonstrated for an iteration scheme in which iterations after enrichment are performed only over a subdomain. Numerical solutions are presented for a one-dimensional infiltration scenario.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/50201/1/1650100302_ftp.pd

    Medical device design for adolescent adherence and developmental goals: a case study of a cystic fibrosis physiotherapy device

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    Purpose: This study investigates the psychosocial aspects of adolescent medical device use and the impact on adolescent adherence and goals for the transitional years between child and adulthood. Patients and methods: Interviews were carried out with 20 adolescents with cystic fibrosis, investigating adolescent medical device use and experiences in relation to their personal and social lives and development through the adolescent years. The qualitative dataset was thematically examined using a content analysis method. Results: The results show that adolescent users of medical technologies want their independence and capabilities to be respected. Adolescent adherence to medical device use was associated with short- and long-term motivations, where older adolescents were able to comprehend the longer-term benefits of use against short-term inconvenience more acutely than younger adolescents. It was suggested that medical devices could provide a tool for communication with families and clinicians and could support adolescents as they take responsibility for managing their condition. Themes of “fitting into teenage life” and “use in the community” were associated with adolescents' needs to form their own identity and have autonomy. Conclusion: This study shows that adolescent needs regarding medical device use are complex. It provides evidence to suggest that devices designed inclusively for adolescents may lead to improved adherence and also facilitate transition through the adolescent years and achievement of adolescent goals

    Short assessment of the Big Five: robust across survey methods except telephone interviewing

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    We examined measurement invariance and age-related robustness of a short 15-item Big Five Inventory (BFI–S) of personality dimensions, which is well suited for applications in large-scale multidisciplinary surveys. The BFI–S was assessed in three different interviewing conditions: computer-assisted or paper-assisted face-to-face interviewing, computer-assisted telephone interviewing, and a self-administered questionnaire. Randomized probability samples from a large-scale German panel survey and a related probability telephone study were used in order to test method effects on self-report measures of personality characteristics across early, middle, and late adulthood. Exploratory structural equation modeling was used in order to test for measurement invariance of the five-factor model of personality trait domains across different assessment methods. For the short inventory, findings suggest strong robustness of self-report measures of personality dimensions among young and middle-aged adults. In old age, telephone interviewing was associated with greater distortions in reliable personality assessment. It is concluded that the greater mental workload of telephone interviewing limits the reliability of self-report personality assessment. Face-to-face surveys and self-administrated questionnaire completion are clearly better suited than phone surveys when personality traits in age-heterogeneous samples are assessed

    Temporal trends in the handgrip strength of 2,592,714 adults from 14 countries between 1960 and 2017: A systematic analysis

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    Background: Handgrip strength (HGS) is an excellent marker of functional capability and health in adults, although little is known about temporal trends in adult HGS. Objectives: The aim of this study was to systematically analyze national (country-level) temporal trends in adult HGS, and to examine relationships between national trends in adult HGS and national trends in health-related and socioeconomic/demographic indicators. Methods: Data were obtained from a systematic search of studies reporting temporal trends in HGS for adults (aged ≥20 years) and by examining national fitness datasets. Trends in mean HGS were estimated at the country-sex-age group level by best-fitting sample-weighted linear/polynomial regression models, with national and sub-regional (pooled data across geographically similar countries) trends estimated by a post-stratified population-weighting procedure. Pearson’s correlations quantified relationships between national trends in adult HGS and national trends in health-related and socioeconomic/demographic indicators. Results: Data from 10 studies/datasets were extracted to estimate trends in mean HGS for 2,592,714 adults from 12 high- and 2 upper-middle-income countries (from Asia, Europe and North America) between 1960 and 2017. National trends were few, mixed and generally negligible pre-2000, whereas most countries (75% or 9/12) experienced negligible-to-small declines ranging from an effect size of 0.05 to 0.27, or 0.6 to 6.3%, per decade post-2000. Sex- and age-related temporal differences were negligible. National trends in adult HGS were not significantly related to national trends in health and socioeconomic/demographic indicators. Conclusions: While trends in adult HGS are currently limited to 14 high- and upper-middle-income countries from 3 continents, adult HGS appears to have declined since 2000 (at least among most of the countries in this analysis), which is suggestive of corresponding declines in functional capability and health. PROSPERO registration number: CRD42013003678. KEY POINTS National (country-level) trends in adult handgrip strength (HGS) were few, mixed and generally negligible pre-2000, and generally negligible and indicated declines post-2000 Sex- and age-related temporal differences in adult HGS were negligible-to-small at the country level and negligible at the regional level National trends in adult HGS were not significantly related to national trends in health and socioeconomic/demographic indicator

    The upper thermal limit of epaulette sharks (Hemiscyllium ocellatum) is conserved across three life history stages, sex and body size

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    Owing to climate change, most notably the increasing frequency of marine heatwaves and long-term ocean warming, better elucidating the upper thermal limits of marine fishes is important for predicting the future of species and populations. The critical thermal maximum (CTmax), or the highest temperature a species can tolerate, is a physiological metric that is used to establish upper thermal limits. Among marine organisms, this metric is commonly assessed in bony fishes but less so in other taxonomic groups, such as elasmobranchs (subclass of sharks, rays and skates), where only thermal acclimation effects on CTmax have been assessed. Herein, we tested whether three life history stages, sex and body size affected CTmax in a tropical elasmobranch, the epaulette shark (Hemiscyllium ocellatum), collected from the reef flats surrounding Heron Island, Australia. Overall, we found no difference in CTmax between life history stages, sexes or across a range of body sizes. Findings from this research suggest that the energetically costly processes (i.e. growth, maturation and reproduction) associated with the life history stages occupying these tropical reef flats do not change overall acute thermal tolerance. However, it is important to note that neither embryos developing in ovo, neonates, nor females actively encapsulating egg cases were observed in or collected from the reef flats. Overall, our findings provide the first evidence in an elasmobranch that upper thermal tolerance is not impacted by life history stage or size. This information will help to improve our understanding of how anthropogenic climate change may (or may not) disproportionally affect particular life stages and, as such, where additional conservation and management actions may be required

    Efficacy of noninvasive cardiac imaging tests in diagnosis and management of stable coronary artery disease

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    Ify R Mordi,1,2 Athar A Badar,2 R John Irving,2 Jonathan R Weir-McCall,1 J Graeme Houston,1 Chim C Lang1,2 1Division of Molecular and Clinical Medicine, University of Dundee, Dundee, UK; 2Department of Cardiology, Ninewells Hospital and Medical School, Dundee, UK Abstract: The aim of this review was to discuss the current literature regarding the utility of noninvasive imaging in diagnosis and management of stable coronary artery disease (CAD) including recent data from large randomized trials assessing diagnosis and prognosis. Current guidelines recommend revascularization in patients with refractory angina and in those with potential prognostic benefit. Appropriate risk stratification through noninvasive assessment is important in ensuring patients are not exposed to unnecessary invasive coronary angiograms. The past 20 years have seen an unprecedented expansion in noninvasive imaging modalities for the assessment of stable CAD, with cardiovascular magnetic resonance and computed tomography complementing established techniques such as myocardial perfusion imaging, echocardiography and exercise electrocardiogram. In this review, we examine the current state-of-the-art in noninvasive imaging to provide an up-to-date analysis of current investigation and management options. Keywords: angina, noninvasive imaging, SPECT, stress echo, cardiovascular magnetic resonance, CT coronary angiograph

    Stratigraphy and sedimentology of early Pennsylvanian red beds at Lower Cove, Nova Scotia, Canada: the Little River Formation with redefinition of the Joggins Formation

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    The coastal cliffs along the eastern shore of Chignecto Bay, Nova Scotia contain one of the finest Carboniferous sections in the world. In 1843, Sir William Logan measured the entire section as the first project of the Geological Survey of Canada, and defined eight stratigraphic divisions. We have re-measured a section corresponding almost exactly with Logan’s Division 5 in bed-by-bed detail. The strata are exposed in the wave-cut platform and low-relief bluffs of a 2 km-long section at Lower Cove, near Joggins, north and south of Little River. This 635.8 metre-thick succession until now has been included within the basal part of the Joggins Formation, and overlies the Boss Point Formation. However, the studied strata are lithologically distinct, and are formally recognized as the new Little River Formation. This formation is bounded by regionally important surfaces and is traceable inland for 30 kilometres from its Lower Cove type section. Facies analysis indicates that it represents the deposits of a well-drained alluvial plain dissected by shallow rivers characterized by flashy flow. It can be clearly distinguished from the underlying Boss Point Formation (Logan’s Division 6) by its much smaller channels, and from the overlying Joggins Formation (Logan’s Division 4) by lack of coal seams and bivalve-bearing limestone beds. Palynological assemblages indicate that the Little River Formation is of probable late Namurian to basal Westphalian (basal Langsettian) age, and is a likely time-equivalent of the informal Grand-Anse formation of southeast New Brunswick. Resumé Les falaises côtières longeant le rivage oriental de la baie Chignectou, en Nouvelle-Écosse, abritent l’un des stratotypes carbonifères les plus intéressants dans le monde. Sir William Logan avait mesuré en 1843 l’ensemble du stratotype dans le cadre du premier projet de la Commission géologique du Canada et il avait défini huit divisions stratigraphiques. Nous avons mesuré à nouveau un stratotype correspondant presque exactement dans ses détails couche par couche à la division 5 de Logan. Les strates affleurent dans une plate-forme d’érosion et des falaises de relief émoussé d’un secteur de deux kilomètres de longueur à l’anse Lower, près de Joggins, au nord et au sud de la rivière Little. Cette succession de 635,8 mètres d’épaisseur avait jusqu’à maintenant été incluse à l’intérieur de la partie basale de la Formation de Joggins et elle recouvre la Formation de Boss Point. Les strates étudiées sont cependant lithologiquement distinctes et on les reconnaît officiellement en tant que nouvelle Formation de Little River. Cette formation est limitée par des surfaces importantes à l’échelle régionale; on peut la retracer à l’intérieur des terres sur 30 kilomètres à partir de son stratotype de l’anse Lower. Une analyse du faciès révèle qu’il représente les dépôts d’une plaine alluviale bien drainée, sectionnée par des rivières peu profondes caractérisées par des crues éclair. On peut nettement la distinguer de la Formation sous-jacente de Boss Point (division 6 de Logan), grâce à ses canaux beaucoup plus petits, ainsi que de la Formation sus-jacente de Joggins (division 4 de Logan), par l’absence de couches houillères et de couches de calcaire abritant des lamellibranches. Les assemblages palynologiques révèlent que la Formation de Little River remonte probablement à la période du Namurien tardif au Westphalien basal (Langsettien basal) et qu’elle constitue vraisemblablement un équivalent chronologique de la Formation officieuse de Grande-Anse dans le sud-est du Nouveau-Brunswick
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