Adaptive service discovery on service-oriented and spontaneous sensor systems

Service-oriented architecture, Spontaneous networks, Self-organisation, Self-configuration, Sensor systems, Social patternsNatural and man-made disasters can significantly impact both people and environments. Enhanced effect can be achieved through dynamic networking of people, systems and procedures and seamless integration of them to fulfil mission objectives with service-oriented sensor systems. However, the benefits of integration of services will not be realised unless we have a dependable method to discover all required services in dynamic environments. In this paper, we propose an Adaptive and Efficient Peer-to-peer Search (AEPS) approach for dependable service integration on service-oriented architecture based on a number of social behaviour patterns. In the AEPS network, the networked nodes can autonomously support and co-operate with each other in a peer-to-peer (P2P) manner to quickly discover and self-configure any services available on the disaster area and deliver a real-time capability by self-organising themselves in spontaneous groups to provide higher flexibility and adaptability for disaster monitoring and relief

Intersecting non-SUSY pp-brane with chargeless 0-brane as black pp-brane

Unlike BPS $p$-brane, non-supersymmetric (non-susy) $p$-brane could be either charged or chargeless. As envisaged in [hep-th/0503007], we construct an intersecting non-susy $p$-brane with chargeless non-susy $q$-brane by taking T-dualities along the delocalized directions of the non-susy $q$-brane solution delocalized in $(p-q)$ transverse directions (where $p\geq q$). In general these solutions are characterized by four independent parameters. We show that when $q=0$ the intersecting charged as well as chargeless non-susy $p$-brane with chargeless 0-brane can be mapped by a coordinate transformation to black $p$-brane when two of the four parameters characterizing the solution take some special values. For definiteness we restrict our discussion to space-time dimensions $d=10$. We observe that parameters characterizing the black brane and the related dynamics are in general in a different branch of the parameter space from those describing the brane-antibrane annihilation process. We demonstrate this in the two examples, namely, the non-susy D0-brane and the intersecting non-susy D4 and D0-branes, where the solutions with the explicit microscopic descriptions are known.Comment: 25 page

Thioredoxin reductase system mediates iron binding in IscA and iron delivery for the iron-sulfur cluster assembly in IscU

IscA is a key member of the iron-sulfur cluster assembly machinery found in bacteria and eukaryotes. Previously, IscA was characterized as an alternative iron-sulfur cluster assembly scaffold, as purified IscA can host transient iron-sulfur clusters. However, recent studies indicated that IscA is an iron-binding protein that can provide iron for the iron-sulfur cluster assembly in a proposed scaffold IscU (Ding H., Clark, R. J., and Ding, B. (2004) J. Biol. Chem. 279, 37499-37504). To further elucidate the roles of IscA in the biogenesis of iron-sulfur clusters, we reevaluate the iron binding activity of IscA under physiologically relevant conditions. The results indicate that in the presence of the thioredoxin reductase system, Escherichia coli IscA binds iron with an iron association constant of 2.0 × 1019 M-1 in vitro. Whereas all three components (thioredoxin 1, thioredoxin reductase and NADPH) in the thioredoxin reductase system are essential for mediating the iron binding in IscA, only catalytic amounts of thioredoxin 1 and thioredoxin reductase are required. In contrast, IscU fails to bind iron in the presence of the thioredoxin reductase system, suggesting that the iron binding in IscA is specific. Nevertheless, the thioredoxin reductase system can promote the iron-sulfur cluster assembly in IscU in the presence of the iron-loaded IscA, cysteine desulfurase (IscS), and L-cysteine, demonstrating a physiologically relevant system for the biogenesis of iron-sulfur clusters. The results provide additional evidence for the hypothesis that IscA is capable of recruiting intracellular free iron and delivering the iron for the iron-sulfur cluster assembly in IscU. © 2005 by The American Society for Biochemistry and Molecular Biology, Inc

Learning Correspondence Structures for Person Re-identification

This paper addresses the problem of handling spatial misalignments due to camera-view changes or human-pose variations in person re-identification. We first introduce a boosting-based approach to learn a correspondence structure which indicates the patch-wise matching probabilities between images from a target camera pair. The learned correspondence structure can not only capture the spatial correspondence pattern between cameras but also handle the viewpoint or human-pose variation in individual images. We further introduce a global constraint-based matching process. It integrates a global matching constraint over the learned correspondence structure to exclude cross-view misalignments during the image patch matching process, hence achieving a more reliable matching score between images. Finally, we also extend our approach by introducing a multi-structure scheme, which learns a set of local correspondence structures to capture the spatial correspondence sub-patterns between a camera pair, so as to handle the spatial misalignments between individual images in a more precise way. Experimental results on various datasets demonstrate the effectiveness of our approach.Comment: IEEE Trans. Image Processing, vol. 26, no. 5, pp. 2438-2453, 2017. The project page for this paper is available at http://min.sjtu.edu.cn/lwydemo/personReID.htm arXiv admin note: text overlap with arXiv:1504.0624

Rethinking pulmonary toxicity in advanced non-small cell lung cancer in the era of combining anti-PD-1/PD-L1 therapy with thoracic radiotherapy.

The combination of programmed cell death 1/programmed cell death ligand 1 blockade and thoracic radiotherapy has become the new standard of care in the treatment of locally advanced non-small-cell lung cancer. The information regarding the pulmonary safety of such therapy remains limited to mostly retrospective studies and case reports with a small portion of data from prospective clinical trials. By analyzing the underlying mechanisms of interactions between radiation and immunotherapy from preclinical data and summarizing safety data from relevant clinical studies with pulmonary toxicity, we believe that longer and rigorous follow-up is warranted, to determine if the combination of such modalities is appropriate for patients without risking undue toxicity

CyberLiveApp: a secure sharing and migration approach for live virtual desktop applications in a cloud environment

In recent years we have witnessed the rapid advent of cloud computing, in which the remote software is delivered as a service and accessed by users using a thin client over the Internet. In particular, the traditional desktop application can execute in the remote virtual machines without re-architecture providing a personal desktop experience to users through remote display technologies. However, existing cloud desktop applications mainly achieve isolation environments using virtual machines (VMs), which cannot adequately support application-oriented collaborations between multiple users and VMs. In this paper, we propose a flexible collaboration approach, named CyberLiveApp, to enable live virtual desktop applications sharing based on a cloud and virtualization infrastructure. The CyberLiveApp supports secure application sharing and on-demand migration among multiple users or equipment. To support VM desktop sharing among multiple users, a secure access mechanism is developed to distinguish view privileges allowing window operation events to be tracked to compute hidden window areas in real time. A proxy-based window filtering mechanism is also proposed to deliver desktops to different users. To support application sharing and migration between VMs, we use the presentation streaming redirection mechanism and VM cloning service. These approaches have been preliminary evaluated on an extended MetaVNC. Results of evaluations have verified that these approaches are effective and useful